PCSK9 regulates neuronal apoptosis by adjusting ApoER2 levels and signaling

Circulating Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Regulates VLDLR Protein and Triglyceride Accumulation in Visceral Adipose Tissue

(2011) Anna Roubtsova et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke

(2011) Estelle Rousselet et al.   JOURNAL OF LIPID RESEARCH

Similarities and differences in structure, expression, and functions of VLDLR and ApoER2

(2011) Sunil S Reddy et al.   Molecular Neurodegeneration

Study of the pathways involved in apoptosis induced by PI3K inhibition in cerebellar granule neurons

(2011) Aurelio Vazquez de la Torre et al.   NEUROCHEMISTRY INTERNATIONAL

A Two-step Binding Model of PCSK9 Interaction with the Low Density Lipoprotein Receptor

(2010) Taichi Yamamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E3 Ubiquitin Ligase IDOL Induces the Degradation of the Low Density Lipoprotein Receptor Family Members VLDLR and ApoER2

(2010) Cynthia Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain

(2010) Mali Liu et al.   JOURNAL OF LIPID RESEARCH

PACAP up-regulates the expression of apolipoprotein D in 3T3-L1 adipocytes. DRG/3T3-L1 co-cultures study

(2010) Joanna Kosacka et al.   NEUROSCIENCE RESEARCH

Coupling of the NMDA receptor to neuroprotective and neurodestructive events

(2009) Giles E. Hardingham   BIOCHEMICAL SOCIETY TRANSACTIONS

Inhibition of PCSK9 as a novel strategy for the treatment of hypercholesterolemia

(2009) D. Lopez   DRUG NEWS & PERSPECTIVES

Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation

(2009) Steve Poirier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of oxidative stress and JNK pathway in apoptotic death induced by potassium deprivation and staurosporine in cerebellar granule neurons

(2009) Yazmín Ramiro-Cortés et al.   NEUROCHEMISTRY INTERNATIONAL

The Role of Apolipoprotein E in Alzheimer's Disease

(2009) Jungsu Kim et al.   NEURON

Neuroprotection by c-Jun NH2-terminal kinase inhibitor SP600125 against potassium deprivation–induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry

(2009) M. Yeste-Velasco et al.   NEUROSCIENCE

Reelin signaling antagonizes  -amyloid at the synapse

(2009) M. S. Durakoglugil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PCSK9 binds to multiple receptors and can be functionally inhibited by an EGF-A peptide

(2008) LiXin Shan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The activation and physiological functions of the proprotein convertases

(2008) N SEIDAH et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Genome-wide expression analysis of cells expressing gain of function mutant D374Y-PCSK9

(2008) Trine Ranheim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Reelin Receptors Apoer2 and Vldlr Coordinate the Patterning of Purkinje Cell Topography in the Developing Mouse Cerebellum

(2008) Matt Larouche et al.   PLoS One