Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebrates

Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

(2012) Jalees Rehman et al.   FASEB JOURNAL

The dynamin-related protein DRP-1 and the insulin signaling pathway cooperate to modulate Caenorhabditis elegans longevity

(2011) Christine C. Yang et al.   AGING CELL

Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control

(2011) Derek P. Narendra et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of PINK1-Parkin-mediated mitophagy

(2011) Wolfdieter Springer et al.   Autophagy

The role of mitochondria in apoptosis

(2011) Seon-Yong Jeong et al.   BMB Reports

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

(2011) Jian Zhao et al.   EMBO JOURNAL

MiD49 and MiD51, new components of the mitochondrial fission machinery

(2011) Catherine S Palmer et al.   EMBO REPORTS

The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons

(2011) Wendou Yu et al.   HUMAN MOLECULAR GENETICS

Molecular mechanisms and physiologic functions of mitochondrial dynamics

(2011) H. Otera et al.   JOURNAL OF BIOCHEMISTRY

The complex interplay between mitochondrial dynamics and cardiac metabolism

(2011) Valentina Parra et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Parkin Ubiquitinates Drp1 for Proteasome-dependent Degradation

(2011) Hongxia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion

(2011) F. Anton et al.   JOURNAL OF CELL SCIENCE

Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion

(2011) M. M. Cohen et al.   JOURNAL OF CELL SCIENCE

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1

(2011) Liliane Glauser et al.   JOURNAL OF NEUROCHEMISTRY

Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia

(2011) Hyungsoo Kim et al.   MOLECULAR CELL

Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

(2010) Chuang-Rung Chang et al.   Annals of the New York Academy of Sciences

Mitochondrial Dynamics in Diabetes

(2010) Yisang Yoon et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial morphology and cardiovascular disease

(2010) S.-B. Ong et al.   CARDIOVASCULAR RESEARCH

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

Association of fission proteins with mitochondrial raft-like domains

(2010) L Ciarlo et al.   CELL DEATH AND DIFFERENTIATION

Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation

(2010) C De Palma et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial fission and remodelling contributes to muscle atrophy

(2010) Vanina Romanello et al.   EMBO JOURNAL

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

(2010) Matthew E. Gegg et al.   HUMAN MOLECULAR GENETICS

Perturbations in Mitochondrial Dynamics Induced by Human Mutant PINK1 Can Be Rescued by the Mitochondrial Division Inhibitor mdivi-1

(2010) Mei Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

(2010) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1

(2010) Y.-Y. Park et al.   JOURNAL OF CELL SCIENCE

New insights into the role of mitochondria in aging: mitochondrial dynamics and more

(2010) A. Y. Seo et al.   JOURNAL OF CELL SCIENCE

Mdm36 Is a Mitochondrial Fission-promoting Protein in Saccharomyces cerevisiae

(2010) Miriam Hammermeister et al.   MOLECULAR BIOLOGY OF THE CELL

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

(2010) Jian-Xun Wang et al.   NATURE MEDICINE

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial protein import: from proteomics to functional mechanisms

(2010) Oliver Schmidt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission

(2010) Jason A Mears et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway

(2010) Angela C. Poole et al.   PLoS One

Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin

(2010) E. Ziviani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal mitochondrial dynamics and neurodegenerative diseases

(2009) Bo Su et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Emerging roles of mitochondrial membrane dynamics in health and disease

(2009) Anja Schäfer et al.   BIOLOGICAL CHEMISTRY

Mitochondrial structural and functional dynamics in Huntington's disease

(2009) P. Hemachandra Reddy et al.   BRAIN RESEARCH REVIEWS

Apoptosis Repressor with Caspase Recruitment Domain Contributes to Chemotherapy Resistance by Abolishing Mitochondrial Fission Mediated by Dynamin-Related Protein-1

(2009) J.-X. Wang et al.   CANCER RESEARCH

SLP-2 is required for stress-induced mitochondrial hyperfusion

(2009) Daniel Tondera et al.   EMBO JOURNAL

MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission

(2009) Emélie Braschi et al.   EMBO REPORTS

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS

Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes

(2009) Antonio Zorzano et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Loss of Parkin or PINK1 Function Increases Drp1-dependent Mitochondrial Fragmentation

(2009) A. Kathrin Lutz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

(2009) Ruben K. Dagda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial outer and inner membrane fusion requires a modified carrier protein

(2009) Suzanne Hoppins et al.   JOURNAL OF CELL BIOLOGY

Regulation of OPA1 processing and mitochondrial fusion bym-AAA protease isoenzymes and OMA1

(2009) Sarah Ehses et al.   JOURNAL OF CELL BIOLOGY

Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells

(2009) Brian Head et al.   JOURNAL OF CELL BIOLOGY

Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria

(2009) Yasushi Tamura et al.   JOURNAL OF CELL BIOLOGY

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

(2009) Junko Wakabayashi et al.   JOURNAL OF CELL BIOLOGY

The novel conserved mitochondrial inner-membrane protein MTGM regulates mitochondrial morphology and cell proliferation

(2009) J. Zhao et al.   JOURNAL OF CELL SCIENCE

Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cells

(2009) Jennifer Hom et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease

(2009) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

Mitochondrial Dynamics in Mammalian Health and Disease

(2009) Marc Liesa et al.   PHYSIOLOGICAL REVIEWS

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

(2009) Dong-Hyung Cho et al.   SCIENCE

Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics

(2009) Cécile Sauvanet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mitochondrial function and morphology are impaired inparkin-mutant fibroblasts

(2008) Heather Mortiboys et al.   ANNALS OF NEUROLOGY

Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential

(2008) Olwenn Guillery et al.   BIOLOGY OF THE CELL

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

(2008) E D Michelakis et al.   BRITISH JOURNAL OF CANCER

Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria

(2008) C. Merkwirth et al.   GENES & DEVELOPMENT

Mitochondrial dynamics and apoptosis

(2008) D.-F. Suen et al.   GENES & DEVELOPMENT

Effects of overexpression of Huntingtin proteins on mitochondrial integrity

(2008) Hongmin Wang et al.   HUMAN MOLECULAR GENETICS

Shaping mitochondria: The complex posttranslational regulation of the mitochondrial fission protein DRP1

(2008) Ansgar Santel et al.   IUBMB LIFE

CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology

(2008) Xiao-Jian Han et al.   JOURNAL OF CELL BIOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Identification of a Novel Protein MICS1 that is Involved in Maintenance of Mitochondrial Morphology and Apoptotic Release of Cytochrome c

(2008) Toshihiko Oka et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of Mitochondrial Morphology by USP30, a Deubiquitinating Enzyme Present in the Mitochondrial Outer Membrane

(2008) Nobuhiro Nakamura et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquitin–Proteasome-dependent Degradation of a Mitofusin, a Critical Regulator of Mitochondrial Fusion

(2008) Mickael M.J. Cohen et al.   MOLECULAR BIOLOGY OF THE CELL

The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells

(2008) Shilpa Gandre-Babbe et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial fragmentation in neurodegeneration

(2008) Andrew B. Knott et al.   NATURE REVIEWS NEUROSCIENCE

Mitochondria in Neuroplasticity and Neurological Disorders

(2008) Mark P. Mattson et al.   NEURON

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

(2008) G. M. Cereghetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The kinase domain of mitochondrial PINK1 faces the cytoplasm

(2008) C. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

(2008) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PINK1/Parkin pathway regulates mitochondrial morphology

(2008) A. C. Poole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

(2008) H. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial dynamics and cancer

(2008) Stéphanie Grandemange et al.   SEMINARS IN CANCER BIOLOGY

Mitochondria in cancer cells: what is so special about them?

(2008) Vladimir Gogvadze et al.   TRENDS IN CELL BIOLOGY