Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers
出版年份 2011 全文链接
标题
Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers
作者
关键词
-
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 69, Issue 2, Pages 223-245
出版商
Springer Nature
发表日期
2011-09-15
DOI
10.1007/s00018-011-0809-0
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Integrated genomic analyses of ovarian carcinoma
- (2011) D. Bell et al. NATURE
- DNA Methylome of Familial Breast Cancer Identifies Distinct Profiles Defined by Mutation Status
- (2010) James M. Flanagan et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo
- (2010) V. J. Weston et al. BLOOD
- Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers
- (2010) Henne Holstege et al. BMC CANCER
- DNA repair signature is associated with anthracycline response in triple negative breast cancer patients
- (2010) A. A. Rodriguez et al. BREAST CANCER RESEARCH AND TREATMENT
- Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers
- (2010) A Al-Attar et al. BRITISH JOURNAL OF CANCER
- DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1
- (2010) Sarah A. Martin et al. CANCER CELL
- A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
- (2010) Sreenath V. Sharma et al. CELL
- BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
- (2010) Gemma Molyneux et al. Cell Stem Cell
- DNA Copy Numbers Profiles in Affinity-Purified Ovarian Clear Cell Carcinoma
- (2010) K. T. Kuo et al. CLINICAL CANCER RESEARCH
- A Marker of Homologous Recombination Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Primary Breast Cancer
- (2010) M. Graeser et al. CLINICAL CANCER RESEARCH
- Development of a Functional Assay for Homologous Recombination Status in Primary Cultures of Epithelial Ovarian Tumor and Correlation with Sensitivity to Poly(ADP-Ribose) Polymerase Inhibitors
- (2010) A. Mukhopadhyay et al. CLINICAL CANCER RESEARCH
- Negative feedback loop of BRCA1–BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1
- (2010) Eva Dizin et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- The Relationship of Platinum Resistance and ERCC1 Protein Expression in Epithelial Ovarian Cancer
- (2010) Karina Dahl Steffensen et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Prognostic Relevance of Uncommon Ovarian Histology in Women With Stage III/IV Epithelial Ovarian Cancer
- (2010) Helen J. Mackay et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer
- (2010) Daniel P. Silver et al. JOURNAL OF CLINICAL ONCOLOGY
- Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer
- (2010) Bryan T.J. Hennessy et al. JOURNAL OF CLINICAL ONCOLOGY
- Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
- (2010) Andrew Tutt et al. LANCET
- Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
- (2010) M William Audeh et al. LANCET
- Identification and Management of Women With BRCA Mutations or Hereditary Predisposition for Breast and Ovarian Cancer
- (2010) Sandhya Pruthi et al. MAYO CLINIC PROCEEDINGS
- DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
- (2010) Emelyne Dejeux et al. Molecular Cancer
- Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer
- (2010) M. C. Villarroel et al. MOLECULAR CANCER THERAPEUTICS
- Mismatch repair deficient colorectal cancer in the era of personalized treatment
- (2010) Madeleine Hewish et al. Nature Reviews Clinical Oncology
- Advances in understanding cancer genomes through second-generation sequencing
- (2010) Matthew Meyerson et al. NATURE REVIEWS GENETICS
- 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
- (2010) Peter Bouwman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ARID1AMutations in Endometriosis-Associated Ovarian Carcinomas
- (2010) Kimberly C. Wiegand et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cyclophosphamide Dose Intensification May Circumvent Anthracycline Resistance of p53 Mutant Breast Cancers
- (2010) J. Lehmann-Che et al. ONCOLOGIST
- The Prognostic Value of BRCA1 mRNA Expression Levels Following Neoadjuvant Chemotherapy in Breast Cancer
- (2010) Mireia Margeli et al. PLoS One
- Somatic structural rearrangements in genetically engineered mouse mammary tumors
- (2010) Ignacio Varela et al. GENOME BIOLOGY
- Frequent Activating Mutations of PIK3CA in Ovarian Clear Cell Carcinoma
- (2009) Kuan-Ting Kuo et al. AMERICAN JOURNAL OF PATHOLOGY
- Mechanisms of double-strand break repair in somatic mammalian cells
- (2009) Andrea J. Hartlerode et al. BIOCHEMICAL JOURNAL
- Etiologic factors for male breast cancer in the U.S. Veterans Affairs medical care system database
- (2009) Louise A. Brinton et al. BREAST CANCER RESEARCH AND TREATMENT
- Utility of Gene Promoter Methylation in Prediction of Response to Platinum-Based Chemotherapy in Epithelial Ovarian Cancer (EOC)
- (2009) Parvesh Chaudhry et al. CANCER INVESTIGATION
- High Incidence of Protein-Truncating TP53 Mutations in BRCA1-Related Breast Cancer
- (2009) H. Holstege et al. CANCER RESEARCH
- High Frequency of TP53 Mutation in BRCA1 and Sporadic Basal-like Carcinomas but not in BRCA1 Luminal Breast Tumors
- (2009) E. Manie et al. CANCER RESEARCH
- Analysis of DNA Copy Number Alterations in Ovarian Serous Tumors Identifies New Molecular Genetic Changes in Low-Grade and High-Grade Carcinomas
- (2009) K.-T. Kuo et al. CANCER RESEARCH
- DNA Repair in Mammalian Cells
- (2009) B. Pardo et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A High-Throughput Pharmaceutical Screen Identifies Compounds with Specific Toxicity against BRCA2-Deficient Tumors
- (2009) B. Evers et al. CLINICAL CANCER RESEARCH
- Coordination of DNA Mismatch Repair and Base Excision Repair Processing of Chemotherapy and Radiation Damage for Targeting Resistant Cancers
- (2009) T. J. Kinsella CLINICAL CANCER RESEARCH
- Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair geneMSH2
- (2009) Sarah A. Martin et al. EMBO Molecular Medicine
- Synthetic lethal targeting ofPTENmutant cells with PARP inhibitors
- (2009) Ana M. Mendes-Pereira et al. EMBO Molecular Medicine
- Recurrent copy number alterations inBRCA1-mutated ovarian tumors alter biological pathways
- (2009) Karin Leunen et al. HUMAN MUTATION
- Pathologic Complete Response Rates in Young Women With BRCA1-Positive Breast Cancers After Neoadjuvant Chemotherapy
- (2009) Tomasz Byrski et al. JOURNAL OF CLINICAL ONCOLOGY
- The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type
- (2009) Britta Weigelt et al. JOURNAL OF PATHOLOGY
- Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers
- (2009) T. R. Rebbeck et al. JNCI-Journal of the National Cancer Institute
- Impairment of APE1 Function Enhances Cellular Sensitivity to Clinically Relevant Alkylators and Antimetabolites
- (2009) D. R. McNeill et al. MOLECULAR CANCER RESEARCH
- Utility of DNA Repair Protein Foci for the Detection of Putative BRCA1 Pathway Defects in Breast Cancer Biopsies
- (2009) H. Willers et al. MOLECULAR CANCER RESEARCH
- Long-Range Transcriptional Control of Progesterone Receptor Gene Expression
- (2009) Jamie Bonéy-Montoya et al. MOLECULAR ENDOCRINOLOGY
- Complex landscapes of somatic rearrangement in human breast cancer genomes
- (2009) Philip J. Stephens et al. NATURE
- Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
- (2009) Elgene Lim et al. NATURE MEDICINE
- Eleven years disease-free: role of chemotherapy in metastatic BRCA2-related breast cancer
- (2009) Fleur Huang et al. Nature Reviews Clinical Oncology
- Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity
- (2009) James E. Cleaver et al. NATURE REVIEWS GENETICS
- BRCA1 and its toolbox for the maintenance of genome integrity
- (2009) Michael S.Y. Huen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Multiple functions of MRN in end-joining pathways during isotype class switching
- (2009) Maria Dinkelmann et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers
- (2009) Peter C. Fong et al. NEW ENGLAND JOURNAL OF MEDICINE
- Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer
- (2008) K. P. M. Suijkerbuijk et al. ANNALS OF ONCOLOGY
- Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH
- (2008) Simon A. Joosse et al. BREAST CANCER RESEARCH AND TREATMENT
- Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer
- (2008) S L Lim et al. BRITISH JOURNAL OF CANCER
- Secondary BRCA1 Mutations in BRCA1-Mutated Ovarian Carcinomas with Platinum Resistance
- (2008) E. M. Swisher et al. CANCER RESEARCH
- Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome
- (2008) R. W. Tothill et al. CLINICAL CANCER RESEARCH
- The DNA repair proteins BRCA1 and ERCC1 as predictive markers in sporadic ovarian cancer
- (2008) Johanne Weberpals et al. INTERNATIONAL JOURNAL OF CANCER
- Estrogen Receptor (ER) β or p53 Attenuates ERα-mediated Transcriptional Activation on theBRCA2Promoter
- (2008) Wei Jin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ERCC5Is a Novel Biomarker of Ovarian Cancer Prognosis
- (2008) Christine S. Walsh et al. JOURNAL OF CLINICAL ONCOLOGY
- Cancer incidence in women with Turner syndrome in Great Britain: a national cohort study
- (2008) Minouk J Schoemaker et al. LANCET ONCOLOGY
- Resistance to therapy caused by intragenic deletion in BRCA2
- (2008) Stacey L. Edwards et al. NATURE
- High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
- (2008) S. Rottenberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Invasive lobular carcinoma of the breast: Response to hormonal therapy and outcomes
- (2007) Emad A. Rakha et al. EUROPEAN JOURNAL OF CANCER
- Prediction of response to chemotherapy by ERCC1 immunohistochemistry and ERCC1 polymorphism in ovarian cancer
- (2007) K.D. STEFFENSEN et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Concerning the Origin of Malignant Tumours by Theodor Boveri. Translated and annotated by Henry Harris
- (2007) T. Boveri JOURNAL OF CELL SCIENCE
- Effect ofBRCA1/2Mutations on Long-Term Survival of Patients With Invasive Ovarian Cancer: The National Israeli Study of Ovarian Cancer
- (2007) Angela Chetrit et al. JOURNAL OF CLINICAL ONCOLOGY
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