Receptor-interacting protein (RIP) kinase family

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

RIP Kinases at the Crossroads of Cell Death and Survival

(2009) Wim Declercq et al.   CELL

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

ITCH K63-Ubiquitinates the NOD2 Binding Protein, RIP2, to Influence Inflammatory Signaling Pathways

(2009) MingFang Tao et al.   CURRENT BIOLOGY

LRRK2 in Parkinson’s disease: building an understanding of disease etiology

(2009) Steven P. Braithwaite   FEBS Journal

LRRK2 in Parkinson’s disease: biochemical functions

(2009) Vasanti S. Anand et al.   FEBS Journal

LRRK2 in Parkinson’s disease: function in cells and neurodegeneration

(2009) Philip J. Webber et al.   FEBS Journal

LRRK2gene variation and its contribution to Parkinson disease

(2009) Coro Paisán-Ruiz   HUMAN MUTATION

The Kinase Activity of Rip2 Determines Its Stability and Consequently Nod1- and Nod2-mediated Immune Responses

(2009) Chiara Nembrini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7,in vitro

(2009) Christian Johannes Gloeckner et al.   JOURNAL OF NEUROCHEMISTRY

Induction of RIP-2 kinase by proinflammatory cytokines is mediated via NF-κB signaling pathways and involves a novel feed-forward regulatory mechanism

(2009) Xixi Yin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

RIP2-β: A novel alternative mRNA splice variant of the receptor interacting protein kinase RIP2

(2009) Andreas Krieg et al.   MOLECULAR IMMUNOLOGY

Death receptor signal transducers: nodes of coordination in immune signaling networks

(2009) Nicholas S Wilson et al.   NATURE IMMUNOLOGY

Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease

(2009) Yanping Li et al.   NATURE NEUROSCIENCE

Regulation of LRRK2 Stability by the E3 Ubiquitin Ligase CHIP

(2009) Xiaodong Ding et al.   PLoS One

Metabolomic Profiling in LRRK2-Related Parkinson's Disease

(2009) Krisztina K. Johansen et al.   PLoS One

The WD40 Domain Is Required for LRRK2 Neurotoxicity

(2009) Nathan D. Jorgensen et al.   PLoS One

XIAP mediates NOD signaling via interaction with RIP2

(2009) A. Krieg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

MEKK4 Sequesters RIP2 to Dictate NOD2 Signal Specificity

(2008) Nivedita M. Clark et al.   CURRENT BIOLOGY

The Role of RIP2 in p38 MAPK Activation in the Stressed Heart

(2008) Sebastien Jacquet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRRK2: bridging the gap between sporadic and hereditary Parkinson's disease

(2008) Alexis Elbaz   LANCET NEUROLOGY

The ancestry of LRRK2 Gly2019Ser parkinsonism

(2008) Hani TS Benamer   LANCET NEUROLOGY