Eukaryotic elongation factor 2 kinase confers tolerance to stress conditions in cancer cells

Clinical Value of Eukaryotic Elongation Factor 2 (eEF2) in Non-small Cell Lung Cancer Patients

(2014) Hong-Gang Sun et al.   Asian Pacific Journal of Cancer Prevention

Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy

(2014) Joell J. Gills et al.   Autophagy

Translational regulator eIF2α in tumor

(2014) Qiaoli Zheng et al.   TUMOR BIOLOGY

Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development

(2014) Andre Mencalha et al.   OncoTargets and Therapy

Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells

(2013) Ahmed A. Ashour et al.   APOPTOSIS

c-Jun-mediated anticancer mechanisms of tylophorine

(2013) Cheng-Wei Yang et al.   CARCINOGENESIS

The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation

(2013) Gabriel Leprivier et al.   CELL

Hypoxia Integration in the Serological Proteome Analysis Unmasks Tumor Antigens and Fosters the Identification of Anti-Phospho-eEF2 Antibodies as Potential Cancer Biomarkers

(2013) Marie Grandjean et al.   PLoS One

Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line

(2013) Meizhi Niu et al.   Proteome Science

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

(2012) Sébastien Pyr Dit Ruys et al.   BIOCHEMICAL JOURNAL

Investigating the Kinetic Mechanism of Inhibition of Elongation Factor 2 Kinase by NH125: Evidence of a Common in Vitro Artifact

(2012) Ashwini K. Devkota et al.   BIOCHEMISTRY

The Role of Eukaryotic Elongation Factor 2 Kinase in Rapid Antidepressant Action of Ketamine

(2012) Lisa M. Monteggia et al.   BIOLOGICAL PSYCHIATRY

A Novel Role for Bcl-2 in Regulation of Cellular Calcium Extrusion

(2012) Pawel E. Ferdek et al.   CURRENT BIOLOGY

Upregulation of Trefoil Factor 3 (TFF3) After Rectal Cancer Chemoradiotherapy Is an Adverse Prognostic Factor and a Potential Therapeutic Target

(2012) Enrique Casado et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Phosphorylation of Eukaryotic Elongation Factor 2 (eEF2) by Cyclin A–Cyclin-Dependent Kinase 2 Regulates Its Inhibition by eEF2 Kinase

(2012) Asli A. Hizli et al.   MOLECULAR AND CELLULAR BIOLOGY

Possible steps of complete disassembly of post-termination complex by yeast eEF3 deduced from inhibition by translocation inhibitors

(2012) Shinya Kurata et al.   NUCLEIC ACIDS RESEARCH

Targeted Silencing of Elongation Factor 2 Kinase Suppresses Growth and Sensitizes Tumors to Doxorubicin in an Orthotopic Model of Breast Cancer

(2012) Ibrahim Tekedereli et al.   PLoS One

Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expression

(2011) Yi Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

eEF-2 Kinase Dictates Cross-Talk between Autophagy and Apoptosis Induced by Akt Inhibition, Thereby Modulating Cytotoxicity of Novel Akt Inhibitor MK-2206

(2011) Y. Cheng et al.   CANCER RESEARCH

1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) Induces Phosphorylation of Eukaryotic Elongation Factor-2 (eEF2)

(2011) Zehan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonlethal aluminum maltolate can reduce brain-derived neurotrophic factor-induced Arc expression through interrupting the ERK signaling in SH-SY5Y neuroblastoma cells

(2010) Tsan-Ju Chen et al.   TOXICOLOGY LETTERS

The role of protein synthesis in cell cycling and cancer

(2009) Shai White-Gilbertson et al.   Molecular Oncology

Cell-Specific Induction of Apoptosis by Rationally Designed Bivalent Aptamer-siRNA Transcripts Silencing Eukaryotic Elongation Factor 2

(2008) Ulrich Wullner et al.   CURRENT CANCER DRUG TARGETS

cdc2–cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner

(2008) Ewan M Smith et al.   EMBO JOURNAL