期刊
CELL RESEARCH
卷 23, 期 8, 页码 973-974出版社
INST BIOCHEMISTRY & CELL BIOLOGY
DOI: 10.1038/cr.2013.71
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- Medical Research Council [MC_PC_U127574433, MC_U127574433] Funding Source: Medline
- Biotechnology and Biological Sciences Research Council [BB/K01384X/1] Funding Source: researchfish
- Medical Research Council [MC_U127574433, MC_PC_U127574433] Funding Source: researchfish
- BBSRC [BB/K01384X/1] Funding Source: UKRI
- MRC [MC_U127574433, MC_PC_U127574433] Funding Source: UKRI
CG-rich DNA reader proteins that bind non-methylated CpG sequences have emerged as critical factors to the process of cell differentiation and development. In a recent paper in Nature, Ko et al. show that the CXXC domain protein, IDAX, plays a crucial role as a CG-rich DNA-binding factor in the regulation of Ten-Eleven-Translocation 2 (TET2) protein function.
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