New insights into p53 activation

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

(2009) D P Teufel et al.   ONCOGENE

Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator

(2008) Sonia Lain et al.   CANCER CELL

Chromatin Immunoprecipitation-on-Chip Reveals Stress-Dependent p53 Occupancy in Primary Normal Cells but Not in Established Cell Lines

(2008) H. Shaked et al.   CANCER RESEARCH

SnapShot: p53 Posttranslational Modifications

(2008) Jan-Philipp Kruse et al.   CELL

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute

(2008) E M Michalak et al.   CELL DEATH AND DIFFERENTIATION

The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2–DAXX–HAUSP complex

(2008) Min Sup Song et al.   EMBO JOURNAL

MSL2 Promotes Mdm2-independent Cytoplasmic Localization of p53

(2008) Jan-Philipp Kruse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mdm2 and Mdm4 Loss Regulates Distinct p53 Activities

(2008) J. A. Barboza et al.   MOLECULAR CANCER RESEARCH

Molecular basis of Pirh2-mediated p53 ubiquitylation

(2008) Yi Sheng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

(2008) S. Shangary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE