Article
Medicine, General & Internal
Raquel Almansa, Carmen Herrero-Rodriguez, Misericordia Martinez-Huelamo, Maria del Pilar Vicente-Andres, Jose Angel Nieto-Barbero, Miryam Martin-Ballesteros, Maria del Mar Rodilla-Carvajal, Amanda de la Fuente, Alicia Ortega, Maria Jesus Alonso-Ramos, James Wacker, Oliver Liesenfeld, Timothy E. Sweeney, Jesus F. Bermejo-Martin, Luis Garcia-Ortiz
Summary: The Fever-7 test is a promising host immune mRNA marker for the early identification of respiratory viral infections in the community, showing high sensitivity and specificity in predicting viral infections.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Medicine, General & Internal
Danielle A. Rankin, Lauren S. Peetluk, Stephen Deppen, James Christopher Slaughter, Sophie Katz, Natasha B. Halasa, Nikhil K. Khankari
Summary: This systematic review evaluated diagnostic models used to predict viral acute respiratory infections in children. A total of 18 studies were included, and the results showed that these models performed well in predicting viral-specific influenza. However, there were high risks of bias in the analytic aspects of the studies. External validation is recommended to ensure the accuracy of the models.
Review
Biochemistry & Molecular Biology
Ewa Ostrycharz, Beata Hukowska-Szematowicz
Summary: This article presents key miRNAs involved in viral infections in humans and animals. The authors summarize existing literature data and reveal that 12 miRNAs are mainly involved in human viral infections, while 10 miRNAs are commonly found in animal viral infections. Investigating the roles of these miRNAs can contribute to understanding the pathogenesis of viral diseases and aid in the development of therapeutic agents.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Virology
Hortense Petat, Vincent Gajdos, Francois Angoulvant, Pierre-Olivier Vidalain, Sandrine Corbet, Christophe Marguet, Jacques Brouard, Astrid Vabret, Meriadeg Ar Gouilh
Summary: The study found that in infants with acute bronchiolitis, 90% tested positive for respiratory syncytial virus and 34% for human rhinovirus, with a higher risk of HRV infection in the absence of RSV. This suggests the presence of interference or exclusion mechanisms between HRV and RSV.
Article
Virology
Chantal J. Snoeck, Konstantin Evdokimov, Kinnaly Xaydalasouk, Sodaly Mongkhoune, Aurelie Sausy, Keoudomphone Vilivong, Maude Pauly, Judith M. Hubschen, Somxay Billamay, Claude P. Muller, Antony P. Black
Summary: Respiratory infections are a common reason for medical consultations in children, with human rhinoviruses being the most frequently detected pathogen in Lao children. Influenza A and B viruses combined infection is also common. The study provides recommendations for vaccination and further research.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Hortense Petat, Matthieu Schuers, Christophe Marguet, Xavier Humbert, Francois Le Bas, Andry Rabiaza, Sandrine Corbet, Bryce Leterrier, Astrid Vabret, Meriadeg Ar Gouilh
Summary: This study provides additional information on the relationships between respiratory viruses, which remains limited in primary care.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Biotechnology & Applied Microbiology
Giuseppe Pantaleo, Bruno Correia, Craig Fenwick, Victor S. Joo, Laurent Perez
Summary: Monoclonal antibodies are attractive as potential therapeutics and prophylactics for viral infections due to their high specificity and ability to enhance immune responses. Advances in antibody engineering and structural biology have led to the development of monoclonal antibodies targeting various viruses, and have implications for vaccine design.
NATURE REVIEWS DRUG DISCOVERY
(2022)
Review
Biochemistry & Molecular Biology
Pawel Franczuk, Michal Tkaczyszyn, Maria Kulak, Esabel Domenico, Piotr Ponikowski, Ewa Anita Jankowska
Summary: Viral respiratory infections (VRI) are common and can worsen existing cardiovascular diseases and lead to new complications, especially in COVID-19.
Article
Infectious Diseases
Yuki Furuse, Raita Tamaki, Akira Suzuki, Taro Kamigaki, Michiko Okamoto, Mariko Saito-Obata, Emiko Nakagawa, Mayuko Saito, Edelwisa Segubre-Mercado, Veronica Tallo, Socorro Lupisan, Hitoshi Oshitani
Summary: This study examined the prevalence of respiratory viruses among children with acute respiratory infections in the Philippines. The research found that the prevalence of respiratory viruses in healthcare facilities was significantly higher than in households, with respiratory syncytial virus and rhinovirus being the most common.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Pediatrics
Marco Maglione, Antonia Pascarella, Chiara Botti, Giuseppe Ricci, Fiorella Morelli, Fabiana Camelia, Alberto Micillo, Camilla Cali, Fabio Savoia, Vincenzo Tipo, Antonietta Giannattasio
Summary: This study evaluated the epidemiology of acute respiratory infections in hospitalized children during the third year of the COVID-19 pandemic and found that public health measures aimed at limiting SARS-CoV-2 circulation may have contributed to reducing the circulation of other respiratory viruses. Respiratory syncytial virus (RSV) was the most detected pathogen in positive panels.
Review
Microbiology
Eli Wilber, Julia M. Baker, Paulina A. Rebolledo
Summary: Acute gastroenteritis, caused by viruses in many cases, can be detected more sensitively and rapidly with multiplex pathogen PCR panels. While there is insufficient evidence to recommend routine use of these panels for the average patient, they could be clinically useful in specific scenarios such as epidemiology surveillance and care of immunocompromised patients. Further research is needed to determine the impact of these panels on provider antibiotic prescribing behavior and patient length of stay in clinical practice.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Article
Environmental Sciences
Alejandro Alvaro-Meca, Maria del Carmen Goez, Rosa Resino, Vanesa Matias, Daniel Sepulveda-Crespo, Isidoro Martinez, Salvador Resino
Summary: This study evaluated the association between short-term exposure to environmental factors and hospital admissions for acute viral lower respiratory infections in children under two years old. The results showed that lower temperature, higher relative humidity, and higher concentrations of NO2, SO2, O-3, and PM10 were associated with increased odds of hospital admissions for viral ALRI.
ENVIRONMENTAL RESEARCH
(2022)
Review
Chemistry, Multidisciplinary
Fatemeh Nasrollahi, Reihaneh Haghniaz, Vahid Hosseini, Elham Davoodi, Mahboobeh Mahmoodi, Solmaz Karamikamkar, Mohammad Ali Darabi, Yangzhi Zhu, Junmin Lee, Sibel Emir Diltemiz, Hossein Montazerian, Sivakoti Sangabathuni, Maryam Tavafoghi, Vadim Jucaud, Wujin Sun, Han-Jun Kim, Samad Ahadian, Ali Khademhosseini
Summary: Viral infections are a leading cause of mortality worldwide, with globalization increasing the risk of virus spreading. Micro and nanotechnologies have attracted attention for developing diagnostic platforms for rapid and accurate detection of viral diseases.
Article
Virology
Guohong Zhu, Dan Xu, Yuanyuan Zhang, Tianlin Wang, Lingyan Zhang, Weizhong Gu, Meiping Shen
Summary: The study found that the rates of viral infection in children vary by different ages and seasons, with the highest positivity rate of adenovirus appearing in the preschool period, respiratory syncytial virus being highest in infants, and influenza virus increasing with age. The total positive rate of viral infection in different seasons is highest in winter, with influenza positivity rate also being highest in winter.
Article
Biochemistry & Molecular Biology
Judy Bai, Katherine Ma, Shangyang Xia, Richard Geng, Claire Shen, Limin Jiang, Xi Gong, Hui Yu, Shuguang Leng, Yan Guo
Summary: This study explores the differences in mutational signatures between different races and their association with environmental pollutant exposures. It shows that increased pollution levels are associated with worse cancer prognosis and that Asians may have a genetic or genomic disadvantage concerning aflatoxin exposure.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2023)
