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CarD Tricks and Magic Spots: Mechanisms of Stringent Control in Mycobacteria

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CELL HOST & MICROBE
卷 6, 期 1, 页码 1-2

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CELL PRESS
DOI: 10.1016/j.chom.2009.07.001

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Global reprogramming of bacterial gene expression in response to nutritional stress, the stringent response, is well studied in E. coli. Now Stallings et al. report that Mycobacterium tuberculosis employs a different strategy involving the general transcription factor CarD for growth control and persistence in response to stresses encountered during infection.

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