Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

Self-Renewing Hematopoietic Stem Cell Is the Primary Target in Pathogenesis of Human Chronic Lymphocytic Leukemia

(2011) Yoshikane Kikushige et al.   CANCER CELL

Links between mutant p53 and genomic instability

(2011) Walter Hanel et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hidden order revealed

(2011) Michael E. Flatté   Nature Physics

Myc, Aurora Kinase A and mutant p53 R172H co-operate in a mouse model of metastatic skin carcinoma

(2011) E C Torchia et al.   ONCOGENE

Mutant p53 R248Q but not R248W enhances in vitro invasiveness of human lung cancer NCI-H1299 cells

(2010) Kazuhito Yoshikawa et al.   BIOMEDICAL RESEARCH-TOKYO

Heterozygosity for Hypoxia Inducible Factor 1  Decreases the Incidence of Thymic Lymphomas in a p53 Mutant Mouse Model

(2009) J. A. Bertout et al.   CANCER RESEARCH

The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells

(2009) Angelo Cicalese et al.   CELL

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

p53 Regulates Hematopoietic Stem Cell Quiescence

(2009) Yan Liu et al.   Cell Stem Cell

A common gain of function of p53 cancer mutants in inducing genetic instability

(2009) D P Liu et al.   ONCOGENE

Mutant p53 Gain-of-Function in Cancer

(2009) M. Oren et al.   Cold Spring Harbor Perspectives in Biology

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss

(2008) T. Terzian et al.   GENES & DEVELOPMENT

The R246S hot-spot p53 mutant exerts dominant-negative effects in embryonic stem cells in vitro and in vivo

(2008) M. K. Lee et al.   JOURNAL OF CELL SCIENCE