Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα+ tumorigenesis

Putting the brakes on mammary tumorigenesis: Loss of STAT1 predisposes to intraepithelial neoplasias

(2015) Christine Schneckenleithner et al.   Oncotarget

Loss of STAT1 from Mouse Mammary Epithelium Results in an Increased Neu-Induced Tumor Burden

(2015) Peter J. Klover et al.   NEOPLASIA

JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rationale for Cotargeting These Pathways in Metastatic Breast Cancer

(2012) Adrian Britschgi et al.   CANCER CELL

Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation

(2011) Jennifer F. Raven et al.   CELL CYCLE

Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signalling, promotes alveologenesis and resistance to cell death and contributes to tumourigenesis

(2011) M M Caffarel et al.   CELL DEATH AND DIFFERENTIATION

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

(2011) Lauren L.C. Marotta et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2

(2011) A V Purandare et al.   LEUKEMIA

Distinct stem cells contribute to mammary gland development and maintenance

(2011) Alexandra Van Keymeulen et al.   NATURE

Janus kinase 2 is required for the initiation but not maintenance of prolactin-induced mammary cancer

(2010) K Sakamoto et al.   ONCOGENE

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

(2009) Michael Hedvat et al.   CANCER CELL

Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A

(2009) D. Yamaji et al.   GENES & DEVELOPMENT

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Reciprocal Effects of STAT5 and STAT3 in Breast Cancer

(2009) S. R. Walker et al.   MOLECULAR CANCER RESEARCH

Sp2 regulates interferon-γ-mediated socs1 gene expression

(2009) Martine Letourneur et al.   MOLECULAR IMMUNOLOGY

Prolactin and Breast Cancer Etiology: An Epidemiologic Perspective

(2008) Shelley S. Tworoger et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Transgenic Models to Study Actions of Prolactin in Mammary Neoplasia

(2008) Lisa M. Arendt et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

From Bench to Bedside: Future Potential for the Translation of Prolactin Inhibitors as Breast Cancer Therapeutics

(2008) Charles V. Clevenger et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

JAK2, But Not Src Family Kinases, Is Required for STAT, ERK, and Akt Signaling in Response to Growth Hormone in Preadipocytes and Hepatoma Cells

(2008) Hui Jin et al.   MOLECULAR ENDOCRINOLOGY

The Stat family of transcription factors have diverse roles in mammary gland development

(2008) C.J. Watson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY