Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity

The Contribution of L-Arginine to the Neurotoxicity of Recombinant Tissue Plasminogen Activator following Cerebral Ischemia: A Review of rtPA Neurotoxicity

(2010) George WJ Harston et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity

(2009) A Baron et al.   CELL DEATH AND DIFFERENTIATION

The 2.1-Å Crystal Structure of Native Neuroserpin Reveals Unique Structural Elements That Contribute to Conformational Instability

(2009) Sayaka Takehara et al.   JOURNAL OF MOLECULAR BIOLOGY

Plasmin Potentiates SynapticN-Methyl-D-aspartate Receptor Function in Hippocampal Neurons through Activation of Protease-activated Receptor-1

(2008) Guido Mannaioni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity

(2008) Jose P Lopez-Atalaya et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Low molecular weight contaminants in commercial preparations of plasmin and t-PA activate neurons

(2008) A. L. SAMSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic

(2008) Manuel Yepes et al.   TRENDS IN NEUROSCIENCES