Illicit survival of cancer cells during polyploidization and depolyploidization

Persistent Telomere Damage Induces Bypass of Mitosis and Tetraploidy

(2010) Teresa Davoli et al.   CELL

Aurora Kinase A Promotes Ovarian Tumorigenesis through Dysregulation of the Cell Cycle and Suppression of BRCA2

(2010) G. Yang et al.   CLINICAL CANCER RESEARCH

Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos

(2010) Ilio Vitale et al.   EMBO JOURNAL

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism

(2010) Sarah L. Thompson et al.   JOURNAL OF CELL BIOLOGY

Ectopic expression of the microtubule-dependent motor protein Eg5 promotes pancreatic tumourigenesis

(2010) Min Liu et al.   JOURNAL OF PATHOLOGY

Depletion of the oncoprotein Bcl-3 induces centrosome amplification and aneuploidy in cancer cells

(2010) Ruben Zamora et al.   Molecular Cancer

p53 suppresses structural chromosome instability after mitotic arrest in human cells

(2010) W B Dalton et al.   ONCOGENE

Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53

(2010) T Fishler et al.   ONCOGENE

DNA Lesions Induced by Replication Stress Trigger Mitotic Aberration and Tetraploidy Development

(2010) Yosuke Ichijima et al.   PLoS One

Plk4 is required for cytokinesis and maintenance of chromosomal stability

(2010) C. O. Rosario et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteins Required for Centrosome Clustering in Cancer Cells

(2010) B. Leber et al.   Science Translational Medicine

Centrosomes and cancer: how cancer cells divide with too many centrosomes

(2009) Susana A. Godinho et al.   CANCER AND METASTASIS REVIEWS

Aurora B-Mediated Abscission Checkpoint Protects against Tetraploidization

(2009) Patrick Steigemann et al.   CELL

Myoblast fusion: When it takes more to make one

(2009) Kate Rochlin et al.   DEVELOPMENTAL BIOLOGY

Deregulated Aurora-B induced tetraploidy promotes tumorigenesis

(2009) Hao G. Nguyen et al.   FASEB JOURNAL

Endoreplication: polyploidy with purpose

(2009) H. O. Lee et al.   GENES & DEVELOPMENT

TTK/hMps1 Mediates the p53-Dependent Postmitotic Checkpoint by Phosphorylating p53 at Thr18

(2009) Y.-F. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Somatic tetraploidy in specific chick retinal ganglion cells induced by nerve growth factor

(2009) S. M. Morillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Centrosome function in cancer: guilty or innocent?

(2009) Deborah Zyss et al.   TRENDS IN CELL BIOLOGY

Enterococcus faecalis Induces Aneuploidy and Tetraploidy in Colonic Epithelial Cells through a Bystander Effect

(2008) X. Wang et al.   CANCER RESEARCH

A Tale of Too Many Centrosomes

(2008) Ceyda Acilan et al.   CELL

Centrosome Amplification Can Initiate Tumorigenesis in Flies

(2008) Renata Basto et al.   CELL

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

(2008) M. Kwon et al.   GENES & DEVELOPMENT

The consequences of tetraploidy and aneuploidy

(2008) Z. Storchova et al.   JOURNAL OF CELL SCIENCE

Id1 Overexpression Induces Tetraploidization and Multiple Abnormal Mitotic Phenotypes by Modulating Aurora A

(2008) Cornelia Man et al.   MOLECULAR BIOLOGY OF THE CELL

Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation

(2008) Clas B. Johansson et al.   NATURE CELL BIOLOGY

Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion

(2008) Jens M. Nygren et al.   NATURE CELL BIOLOGY

Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy

(2008) S Finkin et al.   ONCOGENE

When the Genome Plays Dice: Circumvention of the Spindle Assembly Checkpoint and Near-Random Chromosome Segregation in Multipolar Cancer Cell Mitoses

(2008) David Gisselsson et al.   PLoS One

A Role for Polyploidy in the Tumorigenicity of Pim-1-Expressing Human Prostate and Mammary Epithelial Cells

(2008) Meejeon Roh et al.   PLoS One

Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells

(2008) B. R. Williams et al.   SCIENCE

Essential Role of DAP12 Signaling in Macrophage Programming into a Fusion-Competent State

(2008) L. Helming et al.   Science Signaling

Defining ‘chromosomal instability’

(2008) Jochen B. Geigl et al.   TRENDS IN GENETICS