标题
Wee1 kinase as a target for cancer therapy
作者
关键词
-
出版物
CELL CYCLE
Volume 12, Issue 19, Pages 3348-3353
出版商
Informa UK Limited
发表日期
2013-09-30
DOI
10.4161/cc.26062
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Preclinical Evaluation of the WEE1 Inhibitor MK-1775 as Single-Agent Anticancer Therapy
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- Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells
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- High Expression of Wee1 Is Associated with Poor Disease-Free Survival in Malignant Melanoma: Potential for Targeted Therapy
- (2012) Gry Irene Magnussen et al. PLoS One
- WEE1 inhibition sensitizes osteosarcoma to radiotherapy
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- Chk1 inhibition and Wee1 inhibition combine synergistically to impede cellular proliferation
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- MK-1775, a Potent Wee1 Inhibitor, Synergizes with Gemcitabine to Achieve Tumor Regressions, Selectively in p53-Deficient Pancreatic Cancer Xenografts
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- MK-1775, a Novel Wee1 Kinase Inhibitor, Radiosensitizes p53-Defective Human Tumor Cells
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- Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease
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- WEE1 Inhibition Sensitizes Basal Breast Cancer Cells to TRAIL-Induced Apoptosis
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- MK1775, a Selective Wee1 Inhibitor, Shows Single-Agent Antitumor Activity against Sarcoma Cells
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- The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings
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- Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition
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- Novel insights into maintaining genomic integrity: Wee1 regulating Mus81/Eme1
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- MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil
- (2010) Hiroshi Hirai et al. CANCER BIOLOGY & THERAPY
- In Silico Analysis of Kinase Expression Identifies WEE1 as a Gatekeeper against Mitotic Catastrophe in Glioblastoma
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- Hsp90 phosphorylation, Wee1 and the cell cycle
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- Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
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- Swe1Wee1-Dependent Tyrosine Phosphorylation of Hsp90 Regulates Distinct Facets of Chaperone Function
- (2010) Mehdi Mollapour et al. MOLECULAR CELL
- Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome
- (2009) Lyndsay M. Murrow et al. BREAST CANCER RESEARCH AND TREATMENT
- Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents
- (2009) H. Hirai et al. MOLECULAR CANCER THERAPEUTICS
- Cdk1 Participates in BRCA1-Dependent S Phase Checkpoint Control in Response to DNA Damage
- (2009) Neil Johnson et al. MOLECULAR CELL
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets
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