The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3

DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death

(2015) Richard Hill et al.   Oncotarget

p21WAF1is component of a positive feedback loop that maintains the p53 transcriptional program

(2011) Lisa Y. Pang et al.   CELL CYCLE

Double null cells reveal that CBP and p300 are dispensable for p53 targetsp21andMdm2but variably required for target genes of other signaling pathways

(2011) Lawryn H. Kasper et al.   CELL CYCLE

Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes

(2010) Nathan P. Gomes et al.   CELL CYCLE

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding

(2010) N. P. Gomes et al.   GENES & DEVELOPMENT

Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation

(2010) A. Pickard et al.   JOURNAL OF CELL SCIENCE

Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway

(2010) Ricardo E. Perez et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Lack of p21 expression links cell cycle control and appendage regeneration in mice

(2010) K. Bedelbaeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Senescence impairs successful reprogramming to pluripotent stem cells

(2009) A. Banito et al.   GENES & DEVELOPMENT

A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint

(2009) R. Beckerman et al.   GENES & DEVELOPMENT

Regulation of the p53 transcriptional response by structurally diverse core promoters

(2009) J. M. Morachis et al.   GENES & DEVELOPMENT

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

The Ink4/Arf locus is a barrier for iPS cell reprogramming

(2009) Han Li et al.   NATURE

Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma

(2009) C Zhu et al.   ONCOGENE

CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53

(2009) D. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of p21 by p65 in p53 null cells treated with Doxorubicin

(2008) Shenglin Ma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Multivalent Binding of p53 to the STAGA Complex Mediates Coactivator Recruitment after UV Damage

(2008) A. M. Gamper et al.   MOLECULAR AND CELLULAR BIOLOGY

A New Coactivator Function for Zac1's C2H2 Zinc Finger DNA-Binding Domain in Selectively Controlling PCAF Activity

(2008) A. Hoffmann et al.   MOLECULAR AND CELLULAR BIOLOGY