Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation

Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells

(2016) Yiping Huang et al.   Aging-US

NSP 5a3a: A Potential Novel Cancer Target in Head and Neck Carcinoma

(2015)   Oncotarget

A microRNA-dependent circuit controlling p63/p73 homeostasis: p53 family cross-talk meets therapeutic opportunity

(2015) Benjamin Ory et al.   Oncotarget

miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma

(2015) Nijiro Nohata et al.   Oncotarget

Aurora Kinase Inhibition Overcomes Cetuximab Resistance in Squamous Cell Cancer of the Head and Neck

(2015) Alexander Hoellein et al.   Oncotarget

Coordinate activation of autophagy and the proteasome pathway by FoxO transcription factor

(2014) Jinghui Zhao et al.   Autophagy

Autophagy functions in programmed cell death

(2014) Deborah L. Berry et al.   Autophagy

Autophagy delays apoptosis in renal tubular epithelial cells in cisplatin cytotoxicity

(2014) Gur P. Kaushal et al.   Autophagy

A dual role of p53 in the control of autophagy

(2014) Ezgi Tasdemir et al.   Autophagy

Does bafilomycin A1block the fusion of autophagosomes with lysosomes?

(2014) Daniel J. Klionsky et al.   Autophagy

Bcl-2 family members: Dual regulators of apoptosis and autophagy

(2014) Beth Levine et al.   Autophagy

Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells

(2014) Hua Zhu et al.   Autophagy

The end of autophagic cell death?

(2012) Shensi Shen et al.   Autophagy

Cleaving Beclin 1 to suppress autophagy in chemotherapy-induced apoptosis

(2011) Hua Li et al.   Autophagy

A critical role for UVRAG in apoptosis

(2011) Xiaocheng Yin et al.   Autophagy

Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

(2011) Tracey R. O’Donovan et al.   Autophagy

Systems biology of the autophagy-lysosomal pathway

(2011) Anil G. Jegga et al.   Autophagy

Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells

(2011) Guangmin Xi et al.   CANCER LETTERS

 Np63  Confers Tumor Cell Resistance to Cisplatin through the AKT1 Transcriptional Regulation

(2011) T. Sen et al.   CANCER RESEARCH

ATM kinase is a master switch for the ΔNp63α phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage

(2011) Yiping Huang et al.   CELL CYCLE

Regulation of ΔNp63α by NFκΒ 

(2011) Tanusree Sen et al.   CELL CYCLE

Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure

(2011) Yiping Huang et al.   CELL CYCLE

Schedule-dependent synergy of histone deacetylase inhibitors with DNA damaging agents in small cell lung cancer

(2011) Victoria L. Luchenko et al.   CELL CYCLE

A cisplatin-resistant subpopulation of mesenchymal-like cells in head and neck squamous cell carcinoma

(2011) John B. Sunwoo   CELL CYCLE

Screening for modulators of cisplatin sensitivity: Unbiased screens reveal common themes

(2011) Jeroen H. Nijwening et al.   CELL CYCLE

Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells

(2011) Y Huang et al.   CELL DEATH AND DIFFERENTIATION

Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death

(2011) W Gao et al.   CELL DEATH AND DIFFERENTIATION

Autophagy: Molecular Mechanisms and their Implications for Anticancer Therapies

(2011) S. Meschini et al.   CURRENT CANCER DRUG TARGETS

UV irradiation resistance-associated gene suppresses apoptosis by interfering with BAX activation

(2011) Xiaocheng Yin et al.   EMBO REPORTS

p62/SQSTM1 involved in cisplatin resistance in human ovarian cancer cells by clearing ubiquitinated proteins

(2011) Huimei Yu et al.   EUROPEAN JOURNAL OF CANCER

A microRNA-dependent program controls p53-independent survival and chemosensitivity in human and murine squamous cell carcinoma

(2011) Benjamin Ory et al.   JOURNAL OF CLINICAL INVESTIGATION

Posttranscriptional regulation of miRNAs in the DNA damage response

(2011) Xinna Zhang et al.   RNA Biology

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

ATM engages the TSC2/mTORC1 signaling node to regulate autophagy

(2010) Angela Alexander et al.   Autophagy

Autophagic degradation of active caspase-8

(2010) Wen Hou et al.   Autophagy

DAMP-mediated autophagy contributes to drug resistance

(2010) Liying Liu et al.   Autophagy

Autophagy is a therapeutic target in anticancer drug resistance

(2010) Suning Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Acquired Cisplatin Resistance in Human Lung Adenocarcinoma Cells Is Associated with Enhanced Autophagy

(2010) Jing-Hua Ren et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells

(2010) Yang Sun et al.   CANCER LETTERS

Combination Effects of Salvianolic Acid B with Low-Dose Celecoxib on Inhibition of Head and Neck Squamous Cell Carcinoma Growth In vitro and In vivo

(2010) Y. Zhao et al.   Cancer Prevention Research

Phospho-ΔNp63α/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure

(2010) Yiping Huang et al.   CELL CYCLE

Crosstalk between apoptosis and autophagy within the Beclin 1 interactome

(2010) Maria Chiara Maiuri et al.   EMBO JOURNAL

Concomitant inhibition of AKT and autophagy is required for efficient cisplatin-induced apoptosis of metastatic skin carcinoma

(2010) Sofie Claerhout et al.   INTERNATIONAL JOURNAL OF CANCER

AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells

(2010) L. Harhaji-Trajkovic et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

ΔNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation

(2010) Ashley L Craig et al.   Molecular Cancer

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

(2010) D Tang et al.   ONCOGENE

p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation

(2010) R. Scherz-Shouval et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive analysis of expression pattern and promoter regulation of human autophagy-related genes

(2009) Yusuke Kusama et al.   APOPTOSIS

mTOR regulates autophagy-associated genes downstream of p73

(2009) Jennifer M. Rosenbluth et al.   Autophagy

Atg14 and UVRAG: Mutually exclusive subunits of mammalian Beclin 1-PI3K complexes

(2009) Eisuke Itakura et al.   Autophagy

PARP-1 is involved in autophagy induced by DNA damage

(2009) José Antonio Muñoz-Gámez et al.   Autophagy

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Cisplatin-induced macroautophagy occurs prior to apoptosis in proximal tubules in vivo

(2009) Kosuke Inoue et al.   Clinical and Experimental Nephrology

Autophagy genes as tumor suppressors

(2009) Chengyu Liang et al.   CURRENT OPINION IN CELL BIOLOGY

Apoptosis and autophagy: Regulation of apoptosis by DNA damage signalling - roles of p53, p73 and HIPK2

(2009) Nadja Bitomsky et al.   FEBS Journal

The RNA-induced Silencing Complex: A Versatile Gene-silencing Machine

(2009) Ashley J. Pratt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA Expression Profiling in Human Ovarian Cancer: miR-214 Induces Cell Survival and Cisplatin Resistance by Targeting PTEN

(2008) H. Yang et al.   CANCER RESEARCH

Control of autophagy by oncogenes and tumor suppressor genes

(2008) M C Maiuri et al.   CELL DEATH AND DIFFERENTIATION

Vitamin E Succinate Induces Ceramide-Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma In vitro and In vivo

(2008) X. Gu et al.   CLINICAL CANCER RESEARCH

E2F1 regulates autophagy and the transcription of autophagy genes

(2008) S Polager et al.   ONCOGENE