Decreased translation of p21waf1mRNA causes attenuated p53 signaling in some p53 wild-type tumors

Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel

(2011) Kristen M Garner et al.   BMC CANCER

Targeting the Replication Checkpoint Using SCH 900776, a Potent and Functionally Selective CHK1 Inhibitor Identified via High Content Screening

(2011) T. J. Guzi et al.   MOLECULAR CANCER THERAPEUTICS

Preclinical Development of the Novel Chk1 Inhibitor SCH900776 in Combination with DNA-Damaging Agents and Antimetabolites

(2011) R. Montano et al.   MOLECULAR CANCER THERAPEUTICS

The Microbe-Derived Short Chain Fatty Acid Butyrate Targets miRNA-Dependent p21 Gene Expression in Human Colon Cancer

(2011) Shien Hu et al.   PLoS One

Examination of the expanding pathways for the regulation of p21 expression and activity

(2010) Yong-Sam Jung et al.   CELLULAR SIGNALLING

Deciphering the intricate regulatory mechanisms for the cellular choice between cell repair, apoptosis or senescence in response to damaging signals

(2010) Adnan Erol   CELLULAR SIGNALLING

Multiple microRNAs rescue from Ras-induced senescence by inhibiting p21Waf1/Cip1

(2010) V Borgdorff et al.   ONCOGENE

Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region

(2010) S Wu et al.   ONCOGENE

p21WAF1/CIP1and cancer: A shifting paradigm?

(2009) Andrei L. Gartel   BIOFACTORS

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

MicroRNA 125a and its regulation of the p53 tumor suppressor gene

(2009) Yingjie Zhang et al.   FEBS LETTERS

Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer

(2009) Young-Kook Kim et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs in the miR-106b Family Regulate p21/CDKN1A and Promote Cell Cycle Progression

(2008) I. Ivanovska et al.   MOLECULAR AND CELLULAR BIOLOGY

Defective p53 signaling in p53 wild-type tumors attenuates p21waf1 induction and cyclin B repression rendering them sensitive to Chk1 inhibitors that abrogate DNA damage-induced S and G2 arrest

(2008) A. A. Levesque et al.   MOLECULAR CANCER THERAPEUTICS