Metformin lowers the threshold for stress-induced senescence: A role for the microRNA-200 family and miR-205
出版年份 2012 全文链接
标题
Metformin lowers the threshold for stress-induced senescence: A role for the microRNA-200 family and miR-205
作者
关键词
-
出版物
CELL CYCLE
Volume 11, Issue 6, Pages 1235-1246
出版商
Informa UK Limited
发表日期
2012-03-23
DOI
10.4161/cc.11.6.19665
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cellular senescence controls fibrosis in wound healing
- (2016) Joon-Il Jun et al. Aging-US
- Hormesis does not make sense except in the light of TOR-driven aging
- (2016) Mikhail V. Blagosklonny Aging-US
- Cell cycle arrest is not senescence
- (2016) Mikhail V. Blagosklonny Aging-US
- Hormesis, cell death and aging
- (2016) Isabelle Martins et al. Aging-US
- Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals
- (2011) Meei-Shyuan Lee et al. BMC CANCER
- Obesity and insulin resistance in breast cancer – Chemoprevention strategies with a focus on metformin
- (2011) Pamela J. Goodwin et al. BREAST
- EMT and Stem Cell-Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells
- (2011) C. S. Tellez et al. CANCER RESEARCH
- Autophagy positively regulates the CD44+CD24-/lowbreast cancer stem-like phenotype
- (2011) Sílvia Cufí et al. CELL CYCLE
- Senescence-associated microRNAs linked to tumorigenesis
- (2011) Subramanya Srikantan et al. CELL CYCLE
- Metformin activates an Ataxia Telangiectasia Mutated (ATM)/Chk2-regulated DNA damage-like response
- (2011) Alejandro Vazquez-Martin et al. CELL CYCLE
- Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFβ-induced oncomiR miRNA-181a
- (2011) Cristina Oliveras-Ferraros et al. CELL CYCLE
- mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: A roadmap from energy metabolism to stem cell renewal and aging
- (2011) Javier A. Menendez et al. CELL CYCLE
- miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition
- (2011) A Magenta et al. CELL DEATH AND DIFFERENTIATION
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
- (2011) Athanasia D Panopoulos et al. CELL RESEARCH
- Repositioning chloroquine and metformin to eliminate cancer stem cell traits in pre-malignant lesions
- (2011) Alejandro Vazquez-Martin et al. DRUG RESISTANCE UPDATES
- Four faces of cellular senescence
- (2011) Francis Rodier et al. JOURNAL OF CELL BIOLOGY
- Metformin associated with lower mortality in diabetic patients with early stage hepatocellular carcinoma after radiofrequency ablation
- (2011) Tsung-Ming Chen et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Oncogene-Induced Senescence and its Role in Tumor Suppression
- (2011) Jay P. Reddy et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Integrated Analysis of ATM Mediated Gene and Protein Expression Impacting Cellular Metabolism
- (2011) Amrita K. Cheema et al. JOURNAL OF PROTEOME RESEARCH
- MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells
- (2011) Kayoko Matsushima et al. Journal of Translational Medicine
- Differential expression of oncogenic miRNAs in proliferating and senescent human fibroblasts
- (2011) Miao Wang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Stressed tumor cell, chemosensitized cancer
- (2011) Erik A C Wiemer NATURE MEDICINE
- miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
- (2011) Bogdan Mateescu et al. NATURE MEDICINE
- Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating–cancer stem cells: distinct, overlapping or same populations
- (2011) S Floor et al. ONCOGENE
- Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts
- (2011) Sandra Varum et al. PLoS One
- Elimination of Proliferating Cells Unmasks the Shift from Senescence to Quiescence Caused by Rapamycin
- (2011) Olga V. Leontieva et al. PLoS One
- Senescence and pre-malignancy: How do tumors progress?
- (2011) Raya Saab SEMINARS IN CANCER BIOLOGY
- Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence
- (2011) Lars-Gunnar Larsson SEMINARS IN CANCER BIOLOGY
- Metformin for cancer prevention
- (2011) Yonghua Yang Frontiers of Medicine
- A role for AMPK in increased insulin action after serum starvation
- (2010) James Kain Ching et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis
- (2010) A. DeCensi et al. Cancer Prevention Research
- Metformin and Other Biguanides in Oncology: Advancing the Research Agenda
- (2010) M. Pollak Cancer Prevention Research
- microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network
- (2010) Liming Zhang et al. CARCINOGENESIS
- Metformin against TGFβ-induced epithelial-to-mesenchymal transition (EMT): From cancer stem cells to aging-associated fibrosis
- (2010) Sílvia Cufí et al. CELL CYCLE
- Jailbreak: Oncogene-induced senescence and its evasion
- (2010) Fiona K.E. MDuff et al. CELLULAR SIGNALLING
- Metformin and Energy Metabolism in Breast Cancer: From Insulin Physiology to Tumour-initiating Stem Cells
- (2010) A. Vazquez-Martin et al. CURRENT MOLECULAR MEDICINE
- The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?
- (2010) Simone Brabletz et al. EMBO REPORTS
- The essence of senescence
- (2010) T. Kuilman et al. GENES & DEVELOPMENT
- Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer
- (2010) Erik D. Wiklund et al. INTERNATIONAL JOURNAL OF CANCER
- A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
- (2010) Andrea Alimonti et al. JOURNAL OF CLINICAL INVESTIGATION
- Epithelial-Mesenchymal Transition (EMT) in Tumor-Initiating Cells and Its Clinical Implications in Breast Cancer
- (2010) Chad J. Creighton et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Empowering self-renewal and differentiation: the role of mitochondria in stem cells
- (2010) Jalees Rehman JOURNAL OF MOLECULAR MEDICINE-JMM
- Cancer: A lower bar for senescence
- (2010) Manuel Serrano NATURE
- The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
- (2010) Joon-Il Jun et al. NATURE CELL BIOLOGY
- Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
- (2010) Kaixin Zhou et al. NATURE GENETICS
- Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor
- (2010) Matthew R Janes et al. NATURE MEDICINE
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- Malignant Precursor Cells Pre-Exist in Human Breast DCIS and Require Autophagy for Survival
- (2010) Virginia Espina et al. PLoS One
- MiRNA Profile Associated with Replicative Senescence, Extended Cell Culture, and Ectopic Telomerase Expression in Human Foreskin Fibroblasts
- (2010) Laura N. Bonifacio et al. PLoS One
- Mitochondrial Rejuvenation After Induced Pluripotency
- (2010) Steven T. Suhr et al. PLoS One
- The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells
- (2010) Alessandro Prigione et al. STEM CELLS
- Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to Adriamycin
- (2009) Xu Di et al. BIOCHEMICAL PHARMACOLOGY
- Cellular Senescence in the Development and Treatment of Cancer
- (2009) Gabriele Saretzki CURRENT PHARMACEUTICAL DESIGN
- New Users of Metformin Are at Low Risk of Incident Cancer: A cohort study among people with type 2 diabetes
- (2009) G. Libby et al. DIABETES CARE
- Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes: ZODIAC-16
- (2009) G. W.D. Landman et al. DIABETES CARE
- The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
- (2009) C. J. Currie et al. DIABETOLOGIA
- Senescence induction; a possible cancer therapy
- (2009) Matilde E LLeonart et al. Molecular Cancer
- Elite and stochastic models for induced pluripotent stem cell generation
- (2009) Shinya Yamanaka NATURE
- A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
- (2009) Rosa M. Marión et al. NATURE
- Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
- (2009) Morris E Feldman et al. PLOS BIOLOGY
- Deregulating EMT and Senescence: Double Impact by a Single Twist
- (2008) Marjon A. Smit et al. CANCER CELL
- Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence
- (2008) Stéphane Ansieau et al. CANCER CELL
- Cellular senescence in vivo: a barrier to tumorigenesis
- (2008) Alexandre Prieur et al. CURRENT OPINION IN CELL BIOLOGY
- Zeb1 links epithelial-mesenchymal transition and cellular senescence
- (2008) Y. Liu et al. DEVELOPMENT
- Hormesis [Biological Effects of Low Level Exposures (Belle)] and Dermatology
- (2008) Haw-Yueh Thong et al. Dose-Response
- Cellular life span and the Warburg effect
- (2008) Hiroshi Kondoh EXPERIMENTAL CELL RESEARCH
- The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
- (2008) S.-M. Park et al. GENES & DEVELOPMENT
- The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2
- (2008) Manav Korpal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells
- (2008) Malgorzata A. Sliwinska et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
- (2008) Philip A. Gregory et al. NATURE CELL BIOLOGY
- Hormesis in aging
- (2007) Suresh I.S. Rattan AGEING RESEARCH REVIEWS
- BRCA1 and acetyl-CoA carboxylase: The metabolic syndrome of breast cancer
- (2007) Joan Brunet et al. MOLECULAR CARCINOGENESIS
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