标题
Synthetic lethality of PARP inhibition in cancers lackingBRCA1andBRCA2mutations
作者
关键词
-
出版物
CELL CYCLE
Volume 10, Issue 8, Pages 1192-1199
出版商
Informa UK Limited
发表日期
2011-04-21
DOI
10.4161/cc.10.8.15273
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Contribution of Inherited Mutations in the BRCA2-Interacting Protein PALB2 to Familial Breast Cancer
- (2011) S. Casadei et al. CANCER RESEARCH
- The Aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe
- (2011) Yungan Tao et al. CELL CYCLE
- Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair
- (2011) Arun Gupta et al. CELL CYCLE
- Linking PTEN with genomic instability and DNA repair
- (2011) Raymond E. Meyn CELL CYCLE
- The MRE11 complex: starting from the ends
- (2011) Travis H. Stracker et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Iniparib plus Chemotherapy in Metastatic Triple-Negative Breast Cancer
- (2011) Joyce O'Shaughnessy et al. NEW ENGLAND JOURNAL OF MEDICINE
- Indicators of homologous recombination deficiency in breast cancer and association with response to neoadjuvant chemotherapy
- (2010) E. H. Lips et al. ANNALS OF ONCOLOGY
- The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo
- (2010) V. J. Weston et al. BLOOD
- Mutations in BRCA2 and PALB2 in male breast cancer cases from the United States
- (2010) Yuan Chun Ding et al. BREAST CANCER RESEARCH AND TREATMENT
- Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis
- (2010) Xiaoxia Wang et al. CANCER BIOLOGY & THERAPY
- PALB2/FANCN: Recombining Cancer and Fanconi Anemia
- (2010) M. Tischkowitz et al. CANCER RESEARCH
- PTEN Loss Compromises Homologous Recombination Repair in Astrocytes: Implications for Glioblastoma Therapy with Temozolomide or Poly(ADP-Ribose) Polymerase Inhibitors
- (2010) B. McEllin et al. CANCER RESEARCH
- Aurora Kinase A Promotes Ovarian Tumorigenesis through Dysregulation of the Cell Cycle and Suppression of BRCA2
- (2010) G. Yang et al. CLINICAL CANCER RESEARCH
- A Marker of Homologous Recombination Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Primary Breast Cancer
- (2010) M. Graeser et al. CLINICAL CANCER RESEARCH
- Development of a Functional Assay for Homologous Recombination Status in Primary Cultures of Epithelial Ovarian Tumor and Correlation with Sensitivity to Poly(ADP-Ribose) Polymerase Inhibitors
- (2010) A. Mukhopadhyay et al. CLINICAL CANCER RESEARCH
- Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition
- (2010) Julie K. Horton et al. DNA REPAIR
- Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition
- (2010) Tony Sourisseau et al. EMBO Molecular Medicine
- Double strand break repair components are frequent targets of microsatellite instability in endometrial cancer
- (2010) Cristina Bilbao et al. EUROPEAN JOURNAL OF CANCER
- Prognostic value of microsatellite instability (MSI) and PTEN expression in women with endometrial cancer: Results from studies of the NCIC Clinical Trials Group (NCIC CTG)
- (2010) Helen J. Mackay et al. EUROPEAN JOURNAL OF CANCER
- Aurora-A overexpression and aneuploidy predict poor outcome in serous ovarian carcinoma
- (2010) Heini Lassus et al. GYNECOLOGIC ONCOLOGY
- Increased Chromosomal Radiosensitivity in Women Carrying BRCA1/BRCA2 Mutations Assessed With the G2 Assay
- (2010) Beroukas Ernestos et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Sensitivity to Poly(ADP-ribose) Polymerase (PARP) Inhibition Identifies Ubiquitin-specific Peptidase 11 (USP11) as a Regulator of DNA Double-strand Break Repair
- (2010) Timothy D. Wiltshire et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks
- (2010) T. Hayakawa et al. JOURNAL OF CELL SCIENCE
- Gene Expression Profile ofBRCAness That Correlates With Responsiveness to Chemotherapy and With Outcome in Patients With Epithelial Ovarian Cancer
- (2010) Panagiotis A. Konstantinopoulos et al. JOURNAL OF CLINICAL ONCOLOGY
- BRCA1 CpG Island Hypermethylation Predicts Sensitivity to Poly(Adenosine Diphosphate)- Ribose Polymerase Inhibitors
- (2010) Jurgen Veeck et al. JOURNAL OF CLINICAL ONCOLOGY
- Personalizing Therapy for Ovarian Cancer:BRCAness and Beyond
- (2010) Robert C. Bast et al. JOURNAL OF CLINICAL ONCOLOGY
- Therapeutic Potential of Poly(ADP-ribose) Polymerase Inhibitor AG014699 in Human Cancers With Mutated or Methylated BRCA1 or BRCA2
- (2010) Yvette Drew et al. JNCI-Journal of the National Cancer Institute
- Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
- (2010) Andrew Tutt et al. LANCET
- Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
- (2010) M William Audeh et al. LANCET
- Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer
- (2010) M. C. Villarroel et al. MOLECULAR CANCER THERAPEUTICS
- Sensitization to Radiation and Alkylating Agents by Inhibitors of Poly(ADP-ribose) Polymerase Is Enhanced in Cells Deficient in DNA Double-Strand Break Repair
- (2010) D. A. Loser et al. MOLECULAR CANCER THERAPEUTICS
- ATM Deficiency Sensitizes Mantle Cell Lymphoma Cells to Poly(ADP-Ribose) Polymerase-1 Inhibitors
- (2010) C. T. Williamson et al. MOLECULAR CANCER THERAPEUTICS
- miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors
- (2010) Patryk Moskwa et al. MOLECULAR CELL
- Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination
- (2010) Rémi Buisson et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
- (2010) Eloïse Dray et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- PTEN Deficiency in Endometrioid Endometrial Adenocarcinomas Predicts Sensitivity to PARP Inhibitors
- (2010) K. J. Dedes et al. Science Translational Medicine
- Co-amplification of CCND1 and EMSY is associated with an adverse outcome in ER-positive tamoxifen-treated breast cancers
- (2009) Lindsay A. Brown et al. BREAST CANCER RESEARCH AND TREATMENT
- PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response
- (2009) Feng Zhang et al. CURRENT BIOLOGY
- Synthetic lethal targeting ofPTENmutant cells with PARP inhibitors
- (2009) Ana M. Mendes-Pereira et al. EMBO Molecular Medicine
- MRG15 Is a Novel PALB2-interacting Factor Involved in Homologous Recombination
- (2009) Shirley M.-H. Sy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification and Characterization of a Novel Nuclear Protein Complex Involved in Nuclear Hormone Receptor-mediated Gene Regulation
- (2009) Shivani Garapaty et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Utility of DNA Repair Protein Foci for the Detection of Putative BRCA1 Pathway Defects in Breast Cancer Biopsies
- (2009) H. Willers et al. MOLECULAR CANCER RESEARCH
- PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2
- (2009) F. Zhang et al. MOLECULAR CANCER RESEARCH
- Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers
- (2009) Peter C. Fong et al. NEW ENGLAND JOURNAL OF MEDICINE
- PALB2 is an integral component of the BRCA complex required for homologous recombination repair
- (2009) S. M. H. Sy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of Eukaryotic Homologous Recombination
- (2008) Joseph San Filippo et al. Annual Review of Biochemistry
- Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH
- (2008) Simon A. Joosse et al. BREAST CANCER RESEARCH AND TREATMENT
- A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity
- (2008) Christopher J. Lord et al. DNA REPAIR
- Genetic alterations of CCND1 and EMSY in breast cancers
- (2008) T Kirkegaard et al. HISTOPATHOLOGY
- A Synthetic Lethal Therapeutic Approach: Poly(ADP) Ribose Polymerase Inhibitors for the Treatment of Cancers Deficient in DNA Double-Strand Break Repair
- (2008) Alan Ashworth JOURNAL OF CLINICAL ONCOLOGY
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
- Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
- (2008) Martin F. Lavin NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The role of PTEN signaling perturbations in cancer and in targeted therapy
- (2008) M Keniry et al. ONCOGENE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now