Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition

The RAD6 DNA Damage Tolerance Pathway Operates Uncoupled from the Replication Fork and Is Functional Beyond S Phase

(2010) Georgios I. Karras et al.   CELL

A novel role for fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells

(2010) Ihn Young Song et al.   CELL CYCLE

Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage

(2010) Ting-Hsiang Huang et al.   CELL RESEARCH

FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses

(2010) Fan Zhang et al.   CHROMOSOMA

Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway

(2010) Ihn Young Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network

(2010) Liyi Geng et al.   JOURNAL OF CELL BIOLOGY

Phosphorylated Rad18 directs DNA Polymerase η to sites of stalled replication

(2010) Tovah A. Day et al.   JOURNAL OF CELL BIOLOGY

A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair

(2010) Agata Smogorzewska et al.   MOLECULAR CELL

Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

(2010) P. Pace et al.   SCIENCE

How the Fanconi Anemia Pathway Guards the Genome

(2009) George-Lucian Moldovan et al.   Annual Review of Genetics

Selective accumulation of virus-specific CD8+ T cells within the peripheral blood stem cell compartment

(2009) S. Singh et al.   BLOOD

FANCD2 Hurdles the DNA Interstrand Crosslink

(2009) George-Lucian Moldovan et al.   CELL

DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition

(2009) Yves Pommier   CHEMICAL REVIEWS

Monoubiquitylation in the Fanconi anemia DNA damage response pathway

(2009) A.F. Alpi et al.   DNA REPAIR

Differential Roles for DNA Polymerases Eta, Zeta, and REV1 in Lesion Bypass of Intrastrand versus Interstrand DNA Cross-Links

(2009) J. K. Hicks et al.   MOLECULAR AND CELLULAR BIOLOGY

RAD18 transmits DNA damage signalling to elicit homologous recombination repair

(2009) Jun Huang et al.   NATURE CELL BIOLOGY

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

(2009) Sandie Tuduri et al.   NATURE CELL BIOLOGY

RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1

(2009) Kenji Watanabe et al.   NUCLEIC ACIDS RESEARCH

Fanconi anemia proteins stabilize replication forks

(2008) Lily Chien Wang et al.   DNA REPAIR

Dynamic localization of human RAD18 during the cell cycle and a functional connection with DNA double-strand break repair

(2008) Akiko Inagaki et al.   DNA REPAIR

Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks

(2008) Yuri Tsuji et al.   GENES TO CELLS

DNA Damage-induced Ubiquitylation of RFC2 Subunit of Replication Factor C Complex

(2008) Junya Tomida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

(2008) Arno F. Alpi et al.   MOLECULAR CELL

Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A

(2008) Adelina A. Davies et al.   MOLECULAR CELL

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

(2008) A. Niimi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA