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Aging-suppressants Cellular senescence (hyperactivation) and its pharmacologic deceleration

期刊

CELL CYCLE
卷 8, 期 12, 页码 1883-1887

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TAYLOR & FRANCIS INC
DOI: 10.4161/cc.8.12.8815

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cellular senescence; U0126; LY294002; rapamycin; mTOR; PI-3K; MEK

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Here I overview the accompanying three reports on suppression of cellular senescence with inhibitors of mTOR, PI-3K and MEK. How can growth inhibitors suppress senescence? May these aging-suppressants decelerate organismal aging? To answer these questions, we need to reconsider the meaning of aging.

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