标题
Targeting self-renewal pathways in myeloid malignancies
作者
关键词
Myeloid, Leukemia, Self-renewal, Cross-talk, Therapy, Hematopoietic stem cell
出版物
Cell Communication and Signaling
Volume 11, Issue 1, Pages 33
出版商
Springer Nature
发表日期
2013-05-15
DOI
10.1186/1478-811x-11-33
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Notch pathway activation targets AML-initiating cell homeostasis and differentiation
- (2013) Camille Lobry et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Notch activation inhibits AML growth and survival: a potential therapeutic approach
- (2013) Sankaranarayanan Kannan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Targeting hedgehog in hematologic malignancy
- (2012) D. A. Irvine et al. BLOOD
- Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex
- (2012) Vivian S.W. Li et al. CELL
- Genetic and Pharmacologic Inhibition of β-Catenin Targets Imatinib-Resistant Leukemia Stem Cells in CML
- (2012) Florian H. Heidel et al. Cell Stem Cell
- mTOR Complex 1 Plays Critical Roles in Hematopoiesis and Pten-Loss-Evoked Leukemogenesis
- (2012) Demetrios Kalaitzidis et al. Cell Stem Cell
- Hedgehog Signaling in Hematopoiesis
- (2012) Yiting Lim et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα
- (2012) Hanna S. Radomska et al. JOURNAL OF CLINICAL INVESTIGATION
- CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression
- (2012) Christian Schürch et al. JOURNAL OF CLINICAL INVESTIGATION
- CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling
- (2012) Katrin Faber et al. JOURNAL OF CLINICAL INVESTIGATION
- A role for GPx3 in activity of normal and leukemia stem cells
- (2012) Olivier Herault et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Smad4 binds Hoxa9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by Hoxa9 and leukemia transformation
- (2011) R. Quere et al. BLOOD
- Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor
- (2011) Scott R. Daigle et al. CANCER CELL
- Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia
- (2011) Nicolas Goardon et al. CANCER CELL
- An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
- (2011) J. Zuber et al. GENES & DEVELOPMENT
- The diverse functions of Dot1 and H3K79 methylation
- (2011) A. T. Nguyen et al. GENES & DEVELOPMENT
- Leukemia stem cells
- (2011) Eike C. Buss et al. INTERNATIONAL JOURNAL OF CANCER
- c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells
- (2011) T Waldron et al. LEUKEMIA
- A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia
- (2011) Apostolos Klinakis et al. NATURE
- CAL-101, a p110 selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability
- (2010) B. J. Lannutti et al. BLOOD
- GSK-3 Promotes Conditional Association of CREB and Its Coactivators with MEIS1 to Facilitate HOX-Mediated Transcription and Oncogenesis
- (2010) Zhong Wang et al. CANCER CELL
- β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells
- (2010) Jenny Yeung et al. CANCER CELL
- TGF-β–FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia
- (2010) Kazuhito Naka et al. NATURE
- Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
- (2010) Marc H. G. P. Raaijmakers et al. NATURE
- The Wnt/ -Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
- (2010) Y. Wang et al. SCIENCE
- GSK3 regulates the expressions of human and mouse c-Myb via different mechanisms
- (2010) Kyoko Kitagawa et al. Cell Division
- Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia
- (2009) F. Nakahara et al. BLOOD
- Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal
- (2009) M. Heuser et al. BLOOD
- Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells
- (2009) Masayoshi Kobune et al. CANCER SCIENCE
- Hedgehog Signaling Is Dispensable for Adult Hematopoietic Stem Cell Function
- (2009) Jie Gao et al. Cell Stem Cell
- Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
- (2009) Chen Zhao et al. NATURE
- Glycogen synthase kinase 3 missplicing contributes to leukemia stem cell generation
- (2009) A. E. Abrahamsson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100
- (2008) B. Nervi et al. BLOOD
- Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches
- (2008) P. Rizzo et al. CANCER RESEARCH
- BMP and Wnt Specify Hematopoietic Fate by Activation of the Cdx-Hox Pathway
- (2008) Claudia Lengerke et al. Cell Stem Cell
- Modulation of Notch Signaling by Antibodies Specific for the Extracellular Negative Regulatory Region of NOTCH3
- (2008) Kang Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- β-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemia
- (2008) Y Hu et al. LEUKEMIA
- Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy
- (2008) Zhong Wang et al. NATURE
- Signaling pathways governing stem-cell fate
- (2007) U. Blank et al. BLOOD
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started