Computational Identification of Pathogenic Associated nsSNPs and its Structural Impact in UROD Gene: A Molecular Dynamics Approach

Computational Methods to Work as First-Pass Filter in Deleterious SNP Analysis of Alkaptonuria

(2012) R. Magesh et al.   TheScientificWorldJOURNAL

Performance of mutation pathogenicity prediction methods on missense variants

(2011) Janita Thusberg et al.   HUMAN MUTATION

Comparison of a molecular dynamics model with the X-ray structure of the N370S acid- -glucosidase mutant that causes Gaucher disease

(2011) M. N. Offman et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Computational analysis of missense mutations causing Snyder-Robinson syndrome

(2010) Zhe Zhang et al.   HUMAN MUTATION

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

(2010) Sungsam Gong et al.   PLoS One

Functional annotations improve the predictive score of human disease-related mutations in proteins

(2009) Remo Calabrese et al.   HUMAN MUTATION

Pathogenic or not? And if so, then how? Studying the effects of missense mutations using bioinformatics methods

(2009) Janita Thusberg et al.   HUMAN MUTATION

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

A three-state prediction of single point mutations on protein stability changes

(2008) Emidio Capriotti et al.   BMC BIOINFORMATICS

Analysis of Conformational Changes during Activation of Protein Kinase Pak2 by Amide Hydrogen/Deuterium Exchange

(2008) Yuan-Hao Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Protein interactions in human genetic diseases

(2008) Benjamin Schuster-Böckler et al.   GENOME BIOLOGY