Predicting the Impact of Single-Nucleotide Polymorphisms in CDK2–Flavopiridol Complex by Molecular Dynamics Analysis

In Silico Identification and Analysis of Drug Resistant Mutants of ABL Tyrosine Kinase Based on Detrimental Missense Mutations

(2011) R. Rajasekaran et al.   Current Signal Transduction Therapy

Performance of mutation pathogenicity prediction methods on missense variants

(2011) Janita Thusberg et al.   HUMAN MUTATION

Association between DNA-repair polymorphisms and survival in pancreatic cancer patients treated with combination chemotherapy

(2011) Elisa Giovannetti et al.   PHARMACOGENOMICS

Comparison of a molecular dynamics model with the X-ray structure of the N370S acid- -glucosidase mutant that causes Gaucher disease

(2011) M. N. Offman et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Molecular Basis of Reduced Glucosylceramidase Activity in the Most Common Gaucher Disease Mutant, N370S

(2010) Marc N. Offman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Bruton’s tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

(2009) Abdalla J. Mohamed et al.   IMMUNOLOGICAL REVIEWS

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrated database-pipeline system for studying single nucleotide polymorphisms and diseases

(2008) Jin Ok Yang et al.   BMC BIOINFORMATICS

A three-state prediction of single point mutations on protein stability changes

(2008) Emidio Capriotti et al.   BMC BIOINFORMATICS

Effect of deleterious nsSNP on the HER2 receptor based on stability and binding affinity with herceptin: A computational approach

(2008) R. Rajasekaran et al.   COMPTES RENDUS BIOLOGIES

Analysis of Conformational Changes during Activation of Protein Kinase Pak2 by Amide Hydrogen/Deuterium Exchange

(2008) Yuan-Hao Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and structural comparison of deleterious mutations in nsSNPs of ABL1 gene in chronic myeloid leukemia: A bio-informatics study

(2008) C. George Priya Doss et al.   JOURNAL OF BIOMEDICAL INFORMATICS

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

McKusick's Online Mendelian Inheritance in Man (OMIM(R))

(2008) J. Amberger et al.   NUCLEIC ACIDS RESEARCH

CDK inhibitors in cancer therapy: what is next?

(2007) Marcos Malumbres et al.   TRENDS IN PHARMACOLOGICAL SCIENCES