Functions of the osteocyte network in the regulation of bone mass

Connexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading

(2012) Shane A Lloyd et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteocyte Network; a Negative Regulatory System for Bone Mass Augmented by the Induction of Rankl in Osteoblasts and Sost in Osteocytes at Unloading

(2012) Takeshi Moriishi et al.   PLoS One

Mechanical stress-activated integrin  5 1 induces opening of connexin 43 hemichannels

(2012) N. Batra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyruvate dehydrogenase kinase 4 induces bone loss at unloading by promoting osteoclastogenesis

(2011) Yuying Wang et al.   BONE

Osteocyte apoptosis regulates osteoclast precursor adhesion via osteocytic IL-6 secretion and endothelial ICAM-1 expression

(2011) Wing-Yee Cheung et al.   BONE

Connexin43 deficiency reduces the sensitivity of cortical bone to the effects of muscle paralysis

(2011) Susan K Grimston et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cell autonomous requirement of connexin 43 for osteocyte survival: Consequences for endocortical resorption and periosteal bone formation

(2011) Nicoletta Bivi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Apoptotic osteocytes regulate osteoclast precursor recruitment and differentiation in vitro

(2011) Saja A. Al-Dujaili et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The role of osteocyte apoptosis in cancer chemotherapy-induced bone loss

(2011) Tetyana Shandala et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses

(2011) William F Powell et al.   JOURNAL OF ENDOCRINOLOGY

Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling

(2011) Marcus Watkins et al.   MOLECULAR BIOLOGY OF THE CELL

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered

(2011) A. Moustafa et al.   OSTEOPOROSIS INTERNATIONAL

Enhanced Osteoclastic Resorption and Responsiveness to Mechanical Load in Gap Junction Deficient Bone

(2011) Yue Zhang et al.   PLoS One

Overexpression of Bcl2 in Osteoblasts Inhibits Osteoblast Differentiation and Induces Osteocyte Apoptosis

(2011) Takeshi Moriishi et al.   PLoS One

Role of Endocrine and Paracrine Factors in the Adaptation of Bone to Mechanical Loading

(2011) Joanna S. Price et al.   Current Osteoporosis Reports

PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling

(2010) Yumie Rhee et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Control of RANKL gene expression

(2009) Charles A. O'Brien   BONE

Osteocyte apoptosis and control of bone resorption following ovariectomy in mice

(2009) K.B. Emerton et al.   BONE

Nonpharmacological approaches to improve bone health and reduce osteoporosis

(2009) Pascale Schwab et al.   CURRENT OPINION IN RHEUMATOLOGY

Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β-Catenin Signaling

(2009) Chuwen Lin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Secondary necrosis in multicellular animals: an outcome of apoptosis with pathogenic implications

(2008) Manuel T. Silva et al.   APOPTOSIS

The osteocyte lineage

(2008) Brendon S. Noble   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

Apoptotic Bodies Convey Activity Capable of Initiating Osteoclastogenesis and Localized Bone Destruction

(2008) Giolanta Kogianni et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteocyte Apoptosis Controls Activation of Intracortical Resorption in Response to Bone Fatigue

(2008) Luis Cardoso et al.   JOURNAL OF BONE AND MINERAL RESEARCH