期刊
CELL AND TISSUE RESEARCH
卷 353, 期 2, 页码 339-345出版社
SPRINGER
DOI: 10.1007/s00441-013-1666-y
关键词
Glaucoma; Microglia; Muller glia; Neuroprotection; Retina
类别
Cells of Muller glia and microglia react to neuronal injury in glaucoma. The change to a reactive phenotype initiates signaling cascades that may serve a neuroprotective role, but may also proceed to promote damaging effects on retinal neurons. Both effects appear to occur most likely in parallel in glaucoma, but the underlying mechanisms and signaling pathways that specifically promote protective versus destructive roles of reactive glial cells are mostly unclear. More research is needed to understand the homeostatic signaling network in which retinal glia cells are embedded to maintain or restore neuronal function after injury.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据