Article
Biochemistry & Molecular Biology
Maruf Hasan, Henry Reyer, Michael Oster, Nares Trakooljul, Siriluck Ponsuksilli, Elizabeth Magowan, Dagmar -Christiane Fischer, Klaus Wimmers
Summary: UVB exposure can increase the supply of vitamin D in pig husbandry and does not affect the growth performance of the pigs. After exposure, there are changes in gene expression in the liver, with the pathways for vitamin D synthesis being preferentially initiated.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2024)
Article
Immunology
Khalil Ali Ahmad, Rana Muhammad Shoaib, Muhammad Zaeem Ahsan, Meng-Yan Deng, Le Ma, Evhy Apryani, Xin-Yan Li, Yong-Xiang Wang
Summary: Gabapentinoids alleviate neuropathic pain by stimulating the expression of spinal microglial IL-10 and consequent beta-endorphin.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Article
Neurosciences
Le Ma, Shiyu Peng, Jinbao Wei, Mengjing Zhao, Khalil Ali Ahmad, Jinghong Chen, Yong-Xiang Wang
Summary: This study investigated the regulation of pain hypersensitivity by IL-10 and GLP-1R agonist exenatide in neuropathic rats, showing that spinal microglial expression of beta-endorphin mediates the inhibitory effects.
CNS NEUROSCIENCE & THERAPEUTICS
(2021)
Article
Psychology, Biological
Kalliopi Georgakouli, Eirini Manthou, Panagiotis Georgoulias, Anastasia Ziaka, Chariklia K. Deli, Dimitrios Draganidis, Alexios Batrakoulis, Konstantinos Papanikolaou, Panagiotis Tsimeas, Georgios Mastorakos, Ioannis G. Fatouros, Yiannis Koutedakis, Yannis Theodorakis, Athanasios Z. Jamurtas
Summary: This study investigated the effects of acute exercise on smoking behavior and HPA axis activation in smokers, and found that high intensity exercise increased beta-endorphin levels and delayed smoking, potentially serving as an adjunct in smoking cessation. Differences in HPA axis activation between smokers and non-smokers were observed, with smokers having lower resting levels of beta-endorphin.
PHYSIOLOGY & BEHAVIOR
(2021)
Article
Psychiatry
Ping Wang, Chao Li, Pablo del Sol-Calderon, Leticia Mallol, Elena Hernandez-Alvarez, Encarnacion Donoso-Navarro, Maria Gil-Ligero, Silvia Rosado-Garcia, Antonio Jose Sanchez-Lopez, Marina Martin-Moratinos, Marcos Bella-Fernandez, Hilario Blasco-Fontecilla
Summary: This study analyzed the psychoclinical profile and serum BE level of 39 adolescents admitted to the hospital for SIB in Spain, finding a high serum BE level, a relationship between age of onset of NSSI and SA, and lower BE levels in patients diagnosed with depression.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Chemistry, Physical
Leonardo Vinicius Monteiro de Assis, Paulo Newton Tonolli, Maria Nathalia Moraes, Mauricio S. Baptista, Ana Maria de Lauro Castrucci
Summary: Human skin responses to sunlight involve both the beneficial and harmful effects of UV and visible light, which require a comprehensive understanding of the interactions of photons in the skin and the regulatory role of the light-sensing protein opsins.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS
(2021)
Article
Biochemistry & Molecular Biology
Beatrice Zoanni, Gilda Aiello, Anne Negre-Salvayre, Giancarlo Aldini, Marina Carini, Alfonsina D'Amato
Summary: The lipid profile of skin is important for maintaining the protective barrier against the external environment. UV radiation can cause skin aging, but carnosine has antioxidant properties that can prevent this. This study aimed to investigate the changes in skin lipid composition after UV radiation and the effects of carnosine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Kouji Narita, Krisana Asano, Kyosuke Yamane, Hiroyuki Ohashi, Tatsushi Igarashi, Akio Nakane
Summary: This study reported the germicidal effect of 222 nm UVC and the critical role of bandpass filters in reducing the harmful effects of wavelengths outside of 222 nm on mammalian cells. Mice exposed to UVC emitted from a filtered lamp showed significantly lower levels of DNA damage compared to those exposed to UVC emitted from an unfiltered lamp.
Article
Multidisciplinary Sciences
Andrea L. Hermann, Gillian L. Fell, Lajos Kemeny, Claire Y. Fung, Kathryn D. Held, Peter J. Biggs, Phillip D. Rivera, Staci D. Bilbo, Vivien Igras, Henning Willers, Jong Kung, Liliana Gheorghiu, Katalin Hideghety, Jianren Mao, Clifford J. Woolf, David E. Fisher
Summary: Fatigue is a common adverse effect of radiation therapy in cancer patients. This study suggests that skin-derived beta-endorphin plays a role in radiation-induced fatigue, and opioid antagonism may be a potential treatment for this condition.
Article
Chemistry, Applied
Masaki Honda
Summary: Although most carotenoids in fruits and vegetables exist as the all-E-isomers, several carotenoids accumulated in the skin exist as the Z-isomers. This study investigated the effects of E/Z-isomer ratios of lycopene and beta-carotene on their UV-light-shielding ability and skin-related biological activities. The Z-isomers exhibited higher UV-shielding abilities and greater skin-related biological activities than the all-E-isomers.
Article
Biochemistry & Molecular Biology
Safy Badr, Samar Rezq, Rasha H. Abdelghany
Summary: The study found that Angiotensin II can induce the release of beta-endorphins by increasing IL-1 beta and CRF levels, thereby attenuating the central responses mediated by Angiotensin II. This suggests beta-endorphins as a potential target for treating hypertension.
CHEMICO-BIOLOGICAL INTERACTIONS
(2021)
Article
Dermatology
J. Ahn, D. H. Lee, C. H. Na, D. H. Shim, Y. S. Choi, H. J. Jung, E. L. Simpson
Summary: This study described the clinical features, morphology, and causes of facial dermatitis in patients treated with dupilumab for atopic dermatitis. The majority of patients experienced improvement in their facial dermatitis with dupilumab therapy, but a small proportion of patients had new onset or exacerbation.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Article
Multidisciplinary Sciences
Sladjana Skopelja-Gardner, Joyce Tai, Xizhang Sun, Lena Tanaka, James A. Kuchenbecker, Jessica M. Snyder, Paul Kubes, Tomas Mustelin, Keith B. Elkon
Summary: Exposure to UV light triggers a neutrophil-dependent injury response in the kidney, leading to subclinical renal inflammation and injury. Neutrophils not only migrate to the skin but also to the kidney post UV light exposure, contributing to the renal induction of inflammation and injury genes. Patients with lupus have blood neutrophils similar to those observed in mice post-UV exposure, suggesting a potential role of these cells in mediating inflammation and injury.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Sangeeta Ghuwalewala, Seon A. Lee, Kevin Jiang, Joydeep Baidya, Gopal Chovatiya, Pritinder Kaur, David Shalloway, Tudorita Tumbar
Summary: This study elucidates the molecular and cellular states of basal interfollicular epidermis (IFE) domains and their role in skin adaptation to environmental exposure. The research uncovers two paths of basal cell differentiation and identifies a novel transcription factor, Sox6, that plays an important role in IFE proliferation and survival.
Article
Food Science & Technology
Juliana F. da Silva, Aline T. do B. Morais, Willy G. Santos, Lilia M. Ahrne, Daniel R. Cardoso
Summary: Beta-lactoglobulin (beta-Lg) is a whey protein known for its allergenicity and resistance to digestion. UV-C light-induced cleavage of disulfide bonds in beta-Lg changes its secondary structure, reducing its resistance to pepsin digestion. The reduction of disulfide bonds occurs through direct electron transfer and reaction with a solvated electron. UV-C-treated beta-Lg showed increased gastric digestion index and production of bioactive peptides.
FOOD RESEARCH INTERNATIONAL
(2023)