期刊
CELL
卷 137, 期 2, 页码 213-215出版社
CELL PRESS
DOI: 10.1016/j.cell.2009.04.005
关键词
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资金
- NICHD NIH HHS [P01 HD032062, R01 HD057543, R01 HD057543-02, P01 HD32062] Funding Source: Medline
The Vma21p protein in yeast is an essential assembly chaperone for the vacuolar ATPase, the major proton pump of cellular membranes. In this issue, Ramachandran et al. ( 2009) report that mutations in the gene encoding the human homolog VMA21 cause the disease X-linked myopathy with excessive autophagy through an unexpected mechanism.
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