Article
Chemistry, Multidisciplinary
Haosheng Xin, Zhongxun Xiu, Shijun Liu, Haiyong Wang, Chenguang Wang, Longlong Ma, Qiying Liu
Summary: In this study, alanine was produced from biomass-derived substrates lactic acid and waste glycerol using a series of magnetic catalysts. The Ru/Ni@C catalysts showed remarkable efficiency and selectivity for alanine synthesis.
Review
Chemistry, Applied
Sebastian Stiniya, Padinjare Veetil Saranya, Gopinathan Anilkumar
Summary: N-containing compounds are crucial in nature and synthetic organic chemistry, with N-alkylation reactions playing a significant role in pharmaceuticals and industrial chemical syntheses. Iron-catalyzed N-alkylation reactions have gained acceptance for being environmentally friendly, abundant, non-toxic, biocompatible, reusable, and inexpensive. Green protocols, mild reaction conditions, wide substrate scope, and eco-friendly features make iron-catalyzed N-alkylation reactions prominent in various research fields.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Jiazheng Zhu, Chengjie Duan, Sen Ye, Qizhong Zhang, Kun Li, Guangke He, Xiang Liu, Zhiguo Zhang
Summary: Exploring synthetic methods and catalysts that are easy to handle, highly active, and low-cost for producing industrially important chemicals is a long-term goal in both science and industry. Herein, we present a general and facile Ni-catalyzed reductive amination of aldehydes/ketones methodology using hydrazine as both nitrogen and hydrogen sources, instead of the traditionally used hydrogen gas and ammonia. The mesostructured alumina-supported Ni catalyst with a relatively high ratio of Ni-0 and small-sized Ni nanoparticles plays a critical role in this transformation, resulting in 55 aldehydes/ketones successfully converting to their corresponding primary amines with 61-99% yields. This work outlines a low-cost yet robust catalytic methodology for the facile and general synthesis of primary amines for practical laboratory and industrial application.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Michal Kriegelstein, David Profous, Adam Pribylka, Antonin Lycka, Petr Cankar
Summary: This study used TBBA as a chiral derivatizing agent to evaluate the limits of absolute configuration assignment for beta-chiral aminoalcohols. The results showed that hydrogen bond formation and steric hindrance were the main factors affecting the correct assignment for Boc-aminoalcohols.
Article
Multidisciplinary Sciences
Lin-Xin Ruan, Bo Sun, Jia-Ming Liu, Shi-Liang Shi
Summary: Despite the importance of enantioenriched tertiary alcohols bearing two contiguous stereocenters, their efficient synthesis has remained a challenge. In this study, we report a platform for their preparation using nickel-catalyzed addition of organoboronates to racemic ketones, achieving high levels of diastereo- and enantioselectivity.
Article
Chemistry, Multidisciplinary
Benjamin G. Reed-Berendt, Daniel E. Latham, Mubarak B. Dambatta, Louis C. Morrill
Summary: Borrowing hydrogen is a process used to diversify the synthetic utility of commodity alcohols by oxidizing alcohols to form reactive carbonyl compounds, which can undergo various transformations before the catalyst regenerates. This method has shown significant advances in recent decades, showcasing the diversity of catalysts available and highlighting the potential for further development.
ACS CENTRAL SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Ramin Ghiai, Sedigheh Alavinia, Ramin Ghorbani-Vaghei, Alireza Gharakhani
Summary: This study presents a novel method for synthesizing a porous polymer stabilizer using Fe3O4 magnetic nanoparticles as templates. The synthesized polymer showed a multi-layered structure and was used as a support for a nickel organometallic complex. The resulting nanocomposite exhibited high selectivity and activity as a heterogeneous catalyst in imine synthesis. The synthesized catalyst could be used for eight cycles without significant loss of catalytic efficiency.
Article
Chemistry, Organic
Hidemasa Hikawa, Taku Nakayama, Shunki Nakamura, Shoko Kikkawa, Isao Azumaya
Summary: We present a method for direct amination of benzhydrols using 2-aminopyridines with poor nucleophilic character in water, catalyzed by gold(iii)/sodium diphenylphosphinobenzene-3-sulfonate (TPPMS). The method tolerates various functional groups and generates N-benzylated 2-aminopyridine compounds. Through mechanistic studies, we propose a pathway involving activation of the sp(3) C-O bond of the alcohol by a Lewis acidic gold cation species in the rate-determining step.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Organic
Xiaodong Xiong, Jonathan Wong, Ying-Yeung Yeung
Summary: A facile, efficient, and chemoselective synthesis of allylic amides has been developed using allyl bromides activated by silver triflate. The Ritter-type reaction readily proceeds under mild conditions to give various allyl amides. This protocol is also applicable to different nucleophilic partners to yield a wide range of allyl-substituted products in the absence of a base.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Physical
Yaqi Zhao, Lin Zhang, Yanhui Tang, Min Pu, Ming Lei
Summary: A density functional theory study was conducted to investigate asymmetric ketone hydrogenation catalyzed by Mn complexes, leading to the design of various catalysts with different stereoselectivity. The research provides insights into the design of cheap metal catalysts for asymmetric hydrogenation.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Nanoscience & Nanotechnology
Kaihang Han, Shuo Wang, Qiying Liu, Fagen Wang
Summary: The study demonstrated the synthesis of Ni-Cu alloy nanoparticles for methane dry reforming, showing the impact of Ni/Cu ratio on MDR performance. Addition of a proper quantity of Cu promoted CO2 activation, while excessive Cu formed individual Cu nanoparticles, affecting Ni atoms on the surface and complicating CH4 activation.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Deli Sun, Xianghua Tao, Guobin Ma, Jifen Wang, Yunrong Chen
Summary: We report an asymmetric Ni-catalyzed cross-electrophile coupling approach for the preparation of enantioenriched aryl/vinyl alkyl carbinol esters. The method demonstrates a broad substrate scope and tolerance towards various functional groups.
Article
Chemistry, Organic
Nicolas Joly, Leo Bettoni, Sylvain Gaillard, Albert Poater, Jean-Luc Renaud
Summary: In this study, a new synthesis method for mono- or dialkylated acyl hydrazide compounds was developed using a diaminocyclopentadienone ruthenium tricarbonyl complex-catalyzed borrowing hydrogen strategy with various substituted primary and secondary alcohols as alkylating reagents. Experimental results confirmed that alcohols were the hydrogen source, and density functional theory (DFT) calculations revealed the differences between mono- and dialkylation.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Libing Zhang, Jiaqi Feng, Shoujie Liu, Xingxing Tan, Limin Wu, Shunhan Jia, Liang Xu, Xiaodong Ma, Xinning Song, Jun Ma, Xiaofu Sun, Buxing Han
Summary: CO2 electroreduction plays a crucial role in reducing CO2 emissions and completing the carbon cycle. However, the formation of carbonates and low CO2 utilization efficiency in neutral or alkaline electrolytes hinder its commercial-scale application. In this study, a Ni-Cu dual atom catalyst supported on hollow nitrogen-doped carbon was designed for pH-universal CO2 electroreduction to CO. The catalyst exhibited a high CO Faradaic efficiency of approximately 99% in acidic, neutral, and alkaline electrolytes, with partial current densities of CO reaching 190 +/- 11, 225 +/- 10, and 489 +/- 14 mA cm(-2), respectively. Notably, the CO2 utilization efficiency under acidic conditions reached 64.3%, which was twice as high as that under alkaline conditions. The electronic interaction between Ni and Cu atoms was found to be responsible for the enhanced catalytic performance.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Organic
Rongqing Guan, He Zhao, Min Zhang
Summary: In this study, we have presented a novel annulation reaction for the synthesis of fused tetrahydroquinolines. By utilizing ruthenium catalyst, quinolinium salts can be reacted with indoles and paraformaldehyde to construct a wide range of fused tetrahydroquinolines with syn-diastereoselectivity. The reaction shows mild reaction conditions, excellent substrate and functional group compatibility, readily available feedstocks, and operational simplicity.
