Article
Chemistry, Multidisciplinary
Suresh Moorthy, Alvaro Castillo Bonillo, Hugues Lambert, Elina Kalenius, Tung-Chun Lee
Summary: A new supramolecular approach has been reported to selectively deactivate the electrophilic alpha-carbon of phenyl diazonium ion through host-guest complexation, thus avoiding undesirable side reactions. This method holds great potential for the reactive chemistry of organic molecules in aqueous media.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Organic
Shan Mei, Qi Ou, Xingchen Tang, Jiang-Fei Xu, Xi Zhang
Summary: A host-guest strategy based on cucurbit[7]uril was used to enhance the efficiency of photolysis reactions, resulting in a 40-fold increase in the quantum yield. The stabilization of the contact ion pair by cucurbit[7]uril lowered the Gibbs free energy by 3.06 kcal/mol, as evidenced by DFT calculations. This research provides a novel strategy to improve reactions involving active cations, enriching the field of supramolecular catalysis.
Article
Chemistry, Multidisciplinary
Hang Yin, Roselyne Rosas, Stephane Viel, Michel Giorgi, Valerie Monnier, Laurence Charles, Didier Siri, Didier Gigmes, Youssef Nassar, Floris Chevallier, Christophe Bucher, Ruibing Wang, Anthony Kermagoret, David Bardelang
Summary: This article describes the structural tunability of cucurbit[8]uril (CB[8]) host/guest complexes and their responsiveness to various stimuli in water. A series of versatile 3:2 host/guest complexes were prepared by combining CB[8] with symmetric, linear diviologens, exhibiting remarkable dynamic properties and external ring translocation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Hao Chen, Jin Zhang, Wenting Yu, Yi Cao, Zhaozhen Cao, Yebang Tan
Summary: The study demonstrates the control of viscoelasticity of polymer networks by designing crosslinks with variable molecular dynamics, achieving a quantitative control over mechanical properties and reversible mechanical response. This strategy paves the way for engineering smart responsive materials by tailoring the mechanical properties of polymer networks at the molecular level.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Michele Cariello, Bart Dietrich, Lisa Thomson, Valentina Gauci, Alistair Boyer, Stephen Sproules, Graeme Cooke, Annela Seddon, Dave J. Adams
Summary: A novel flavin-based gelator is reported, which exhibits different structures and catalytic performance at different pH values.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Weiquan Xu, Yang Jiao, Bohan Tang, Jiang-Fei Xu, Xi Zhang
Summary: Utilizing the host-guest interaction of CB[7] effectively modulates the reactivity of anionic enolate and cationic oxonium in alkaline and acidic conditions, respectively, leading to accelerated or decelerated catalysis. The highly polar portals of CB[n] molecules provide a promising way to enrich the toolkit of supramolecular catalysis by modulating the reactivity of various ionic intermediates.
Article
Chemistry, Physical
Nelly F. Nunheim, Werner R. Thiel
Summary: Systematic optimization of the Ru-catalyzed oxidation of alcohols using TBHP as the oxidizing agent was carried out. A sustainable protocol was developed using a water/tert-butanol mixture as the solvent and a syringe pump for continuous addition of the oxidizing agent, resulting in high yields and selectivity.
Review
Chemistry, Multidisciplinary
Ziyi Wang, Chen Sun, Kuikun Yang, Xiaoyuan Chen, Ruibing Wang
Summary: Supramolecular polymers, with their unique features and functions, have attracted broad interest in diverse biomedical applications. This Minireview summarizes the recent progress in the design, fabrication, and biomedical applications of CB[n]-based supramolecular polymers (CSPs), categorized as noncovalent and covalent CSPs. The design principles, advantages, and future perspectives of CSPs in the field of biomedicine are also discussed.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Xue Yang, Qian Cheng, Valerie Monnier, Laurence Charles, Hakim Karoui, Olivier Ouari, Didier Gigmes, Ruibing Wang, Anthony Kermagoret, David Bardelang
Summary: Chemists have successfully mimicked the function of natural molecular machines with synthetic systems in organic solvents and exchanged guest molecules in synthetic macrocycles for the production of pH-responsive hydrogels in water. Cucurbiturils may be excellent ring molecules for the construction of advanced molecular machines working in water.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Xue Yang, Chunyang Li, Michel Giorgi, Didier Siri, Xavier Bugaut, Bastien Chatelet, Didier Gigmes, Mehdi Yemloul, Virginie Hornebecq, Anthony Kermagoret, Sophie Brasselet, Alexandre Martinez, David Bardelang
Summary: Porous organic crystals based on macrocycles have recently shown exceptional sorption and separation properties. In this study, the inclusion of trimethoxybenzyl-azaphosphatrane in the macrocycle cucurbit[8]uril (CB[8]) resulted in the formation of molecular porous host.guest crystals (PHGC-1) with radically new properties. The PHGC-1 crystals demonstrated spontaneous and selective adsorption of iodine at room temperature and atmospheric pressure, offering potential advantages in energy cost reduction.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Materials Science, Multidisciplinary
Zheng-Kun Bai, Qing-Mei Ge, Nan Jiang, Hang Cong, Zhu Tao, Mao Liu, Ying Fan
Summary: A novel supramolecular photocatalyst, g-C3N4/ Ag3PO4@Q [7] composite, with the macrocyclic compound of cucurbit [7]uril (Q [7]) block, is successfully prepared by ternary organic-inorganic hybridization. It is applied for the photo-driven degradation of pyroquilon and admire pesticides in the irradiation of visible light. The photocatalyst exhibits high degradation efficiency, stability, and reusability, offering performance advantages of low energy consumption and fast reaction rates compared to reported photocatalysts.
Article
Chemistry, Multidisciplinary
Xin-Kun Ma, Xiaolu Zhou, Jing Wu, Fang-Fang Shen, Yu Liu
Summary: This study presents a design strategy for achieving near-infrared excitation and emission of organic phosphorescence materials through two-stage confinement supramolecular assembly. The prepared water-soluble assemblies maintain two-photon absorption and multicolor luminescence in cells or vivo, providing potential applications in bioimaging.
Article
Nanoscience & Nanotechnology
Han Wu, Hua Wang, Feilong Qi, Tian Xia, Yu Xia, Jiang-Fei Xu, Xi Zhang
Summary: A new strategy of activatable host-guest conjugate with self-inclusion property is proposed for supramolecular chemotherapy, which can achieve high-efficiency drug release triggered by intramolecular host-guest self-inclusion. The encapsulation of oxaliplatin in the conjugate leads to the formation of a stable supramolecular drug, and the release of oxaliplatin in the tumor microenvironment shows comparable anti-tumor bioactivity to naked oxaliplatin. This research may open new horizons for programmable and on-demand supramolecular chemotherapy with high anti-tumor efficiency.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Materials Science, Multidisciplinary
Cheng Xu, Xiang Yu, Yang Liu, Xiongzhi Zhang, Simin Liu
Summary: In this study, multi-functional and stimulus-responsive hydrogels were successfully prepared by a hybrid supramolecular copolymerization strategy. The obtained hydrogels exhibit excellent mechanical properties, self-healing efficiency, and conductivity, as well as a triple stimulation response to strain, heat, and near-infrared light. This versatile hydrogel can function as a wearable strain sensor and has great potential in flexible electronics and biomedical fields.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Physical
Ayan Bhattacharyya, Suman De Sarkar, Anindita Das
Summary: Visible-light-mediated photoredox catalysis has been developed as an efficient alternative to conventional organic synthesis, with researchers now incorporating supramolecular chemistry techniques to customize traditional catalysts and expand their scope through noncovalent interactions. The use of supramolecular engineering has led to improved efficiency in known chemical reactions and the development of advanced synthetic methodologies. Additionally, self-assembly strategies within confined nanospaces have been shown to impact photocatalytic reactions.
