Article
Chemistry, Physical
Ryouichi Satou, Atsushi Yamagishi, Atsushi Takayanagi, Miyu Iwasaki, Hideyuki Kamijo, Naoki Sugihara
Summary: This study aims to confirm that high concentrations of acid phosphate MFP can provide a highly biosafe fluoride application method that acts through the deep enamel layers. The results show that MFP and AP-MFP treatments can improve the acid resistance of enamel and AP-MFP can act both on the surface layer and deep into the enamel.
Article
Dentistry, Oral Surgery & Medicine
Francyenne Maira Castro Goncalves, Alberto Carlos Botazzo Delbem, Leonardo Fernandes Gomes, Nayara Goncalves Emerenciano, Matheus dos Passos Silva, Mark L. Cannon, Marcelle Danelon
Summary: The 1100F-TMP-MI Paste Plus group showed better results in terms of %SH, ΔKHN, and PLM, with the highest concentration of Ca and P in the enamel among all groups.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Engineering, Biomedical
Sara Tiemi Felipe Akabane, Marcelle Danelon, Gabriel Pereira Nunes, Amanda Scarpin Gruba, Carlos Alberto de Souza-Costa, Carla Caroline de Oliveira Duque, Marjorie de Oliveira Gallinari, Andre Luiz Fraga Briso, Alberto Carlos Botazzo Delbem
Summary: The study concluded that the addition of NaF/TMP in-office bleaching did not interfere with bleaching efficacy, while reducing enamel demineralization, H2O2 penetration, and cytotoxicity.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Chemistry, Physical
Ryouichi Satou, Susumu Ueno, Hideyuki Kamijo, Naoki Sugihara
Summary: The purpose of this study was to assess the prevention of dentin erosion by sodium monofluorophosphate upon exposure to citric acid, and compare its effects to the conventional acidulated phosphate fluoride application method. The results showed that the application of sodium monofluorophosphate significantly reduced defects, mineral loss, and lesion depth in dentin, while maintaining hardness and promoting the aggregation of fine CaF2 particles to seal dentin tubules, enhancing acid resistance.
Article
Dentistry, Oral Surgery & Medicine
Song-Yi Yang, Il Jun Jeong, Kwang-Mahn Kim, Jae-Sung Kwon
Summary: The study found that after APF gel treatment, the hardness of the acid-etched enamel surface decreased with increasing immersion period, and SEM images showed similar etched patterns in the test groups as the immersion period increased. The shear bond strength increased with increasing immersion period, with no significant difference between the F21 group and the control group. Higher adhesive remnant index scores were identified as the ageing period increased.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Chemistry, Multidisciplinary
Felice Femiano, Rossella Femiano, Luigi Femiano, Ludovica Nucci, Martina Santaniello, Vincenzo Grassia, Nicola Scotti, Raffaella Aversa, Valeria Perrotta, Antonio Apicella, Davide Apicella
Summary: This study investigated the protective effect of diode laser irradiation and topical application of fluoride on the erosion of dental enamel. The results showed that laser irradiation and fluoride application could reduce the number and density of enamel prisms, thereby improving the protection against acid erosion.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Physical
Ryouichi Satou, Miyu Iwasaki, Hideyuki Kamijo, Naoki Sugihara
Summary: This study attempted to develop a dental caries prevention method using bioapatite and high-concentration fluoride, which showed reduced enamel loss and improved acid resistance.
Review
Biotechnology & Applied Microbiology
Jiarong Yan, Hongye Yang, Ting Luo, Fang Hua, Hong He
Summary: Enamel demineralization, a common dental problem, is a concern for dental professionals and patients due to its impact on both health and aesthetics. Amorphous calcium phosphate (ACP) has gained attention as a potential agent for preventing or treating enamel demineralization. This article briefly reviews ACP stabilizers and their mechanisms, as well as the scientific evidence supporting the remineralization ability of these agents. The limitations of current research and future prospects for clinical translation of ACP agents are also discussed.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Leticia Goncalves Oliveira, Alberto Carlos Botazzo Delbem, Francyenne Maira Castro Goncalves, Gabriela Leal Peres Fernandes, Mark L. Cannon, Marcell Danelon
Summary: This study aimed to evaluate the effect of toothpaste with reduced fluoride concentration (200 ppm), supplemented with sodium trimetaphosphate (0.2%), Xylitol (16%), and Erythritol (4%) on dental enamel demineralization. The results showed that the combination of 200 ppm F-X-E-TMP treatment significantly increased the protective effect on enamel demineralization compared to 1100 ppm F toothpaste.
JOURNAL OF APPLIED ORAL SCIENCE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Nayara Goncalves Emerenciano, Alberto Carlos Botazzo Delbem, Francyenne Maira Castro Goncalves, Julia Paiao Quinterio, Emerson Rodrigues de Camargo, Yara Teresinha Correa Silva-Sousa, Marcelle Danelon
Summary: The addition of 0.25% nano-sized beta-CaGPn to 1100F formulation increased the bioavailability of calcium and phosphate, promoting a higher level of remineralization.
JOURNAL OF DENTISTRY
(2023)
Article
Chemistry, Physical
Markus Reise, Stefan Kranz, Markus Heyder, Klaus D. Jandt, Bernd W. Sigusch
Summary: This study evaluated the effectiveness of Tooth Mousse compared to conventional fluoride-based versions in preventing enamel and dentin demineralization. Results showed that Tooth Mousse was less effective in preventing demineralization compared to fluoride toothpastes, but using Tooth Mousse during demineralization led to a reduced number of severe lesions.
Article
Dentistry, Oral Surgery & Medicine
Bruna Zancope, Livia Pagotto Rodrigues, Lenita Marangoni Lopes, Emerson Tavares de-Sousa, Carolina Steiner-Oliveira, Lidiany Karla Azevedo Rodrigues, Marines Nobre-dos-Santos
Summary: The combination of FD and CO2 laser treatment effectively inhibits the progression of enamel caries, overcoming the effect of APF.
CLINICAL ORAL INVESTIGATIONS
(2023)
Review
Chemistry, Multidisciplinary
Vicky Wenqing Xue, Irene Shuping Zhao, Iris Xiaoxue Yin, John Yun Niu, Edward Chin Man Lo, Chun Hung Chu
Summary: The study conducted a systematic review on the effect of treatment combining 9300 nm carbon dioxide lasers and fluoride in preventing enamel caries. The results showed that the combination treatment was more effective in preventing enamel demineralization compared to fluoride treatment or laser treatment alone.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Moufida Abufarwa, Amal Noureldin, Phillip M. Campbell, Peter H. Buschang
Summary: The study demonstrated that reapplication of CPP-ACP fluoride varnish every 4-6 weeks is more effective in reducing enamel demineralization compared to every 12 weeks. Significant differences were found in the changes of demineralization area and impact among different time intervals, while intensity remained relatively stable.
JOURNAL OF DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Dina El-Desouky, Azza Hanno, Yasmine Elhamouly, Sara A. Hamza, Lubna M. El-Desouky, Karin M. L. Dowidar
Summary: This study aimed to compare the preventive effects of experimental nano silver fluoride (NSF) formulation and commercial sodium fluoride varnish (FV) on the demineralization of primary teeth enamel. The results showed that both NSF and FV significantly improved the microhardness and reduced lesion depth in comparison to the negative controls. NSF and FV demonstrated similar effectiveness in limiting enamel demineralization caused by acidic challenge.
Article
Dentistry, Oral Surgery & Medicine
Manuela Da Silva Spinola, Livia Maria Andalo Tenuta
Summary: The study found that a calcium pretreatment enhances the reactivity of fluoride with enamel and dentine. Carious substrates had a greater reactivity with fluoride compared to sound substrates, confirming that increased porosity enhances the reactivity with fluoride.
ARCHIVES OF ORAL BIOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Mauro Antonio Dall Agnol, Carla Battiston, Livia Maria Andalo Tenuta, Jaime Aparecido Cury
Summary: Fluoride varnish (FV) and acidulated phosphate fluoride gel (APF-gel) are both effective in reducing dental caries, but FV has slower chemical reactivity. A clinical study found that FV needs to remain on dental surfaces for a longer time (>4 hours) compared to a 4-minute application of APF-gel to achieve the same reactivity.
Article
Dentistry, Oral Surgery & Medicine
Juliana Campos Vieira, Jaime Aparecido Cury, Antonio Pedro Ricomini Filho
Summary: The study suggests that the cariogenicity of lactose exposure at night is enhanced by exposure to sucrose during the day.
Article
Dentistry, Oral Surgery & Medicine
Deborah Rackel Caldas da Rocha, Antonio Pedro Ricomini Filho, Jaime Aparecido Cury
Summary: The concentration of soluble fluoride in toothpaste can predict the systemic bioavailability of fluoride when ingested.
Article
Biochemical Research Methods
Lina M. Marin, Jaime A. Cury, Walter L. Siqueira
Summary: In this study, an in vitro cariogenic Streptococcus mutans biofilm model was modified and validated by assessing the dose-response effect of fluoride on enamel demineralization. The model demonstrated a dose-response effect of fluoride in influencing enamel demineralization, showing the potential for assessing novel biotechnological strategies for caries prevention.
JOURNAL OF MICROBIOLOGICAL METHODS
(2022)
Article
Microbiology
Lina Maria Marin, Yizhi Xiao, Jaime Aparecido Cury, Walter Luiz Siqueira
Summary: This study found that modifying the protein components of the acquired enamel pellicle can influence the adhesion of Streptococcus mutans to dental surfaces. Engineered salivary peptides were shown to modulate the bacterial proteome upon adherence, potentially reducing bacterial colonization and biofilm development.
Article
Microbiology
Lina Maria Marin, Yizhi Xiao, Jaime Aparecido Cury, Walter Luiz Siqueira
Summary: The engineered salivary peptide DR9-RR14 has been shown to effectively reduce enamel demineralization, but has no significant impact on biofilm biomass or the expression of cariogenic bacterial proteins. This suggests that DR9-RR14 may primarily control caries development through a physicochemical mechanism.
Article
Dentistry, Oral Surgery & Medicine
Nathan A. Jones, Wendy Bloembergen, Livia M. A. Tenuta, Susan E. Flannagan, Glenn W. Jones, Li-Chi Pan, Mariah Newton, Brian H. Clarkson, Joerg Lahann, Steven Bloembergen, Carlos Gonzalez-Cabezas
Summary: Fluorescent cationic starch nanoparticles (FCSNs) have been shown to penetrate enamel surface porosity of carious lesions, aiding in their detection. This study evaluated the accuracy of FCSNs in detecting occlusal caries and found them to have high sensitivity and specificity. Further clinical validation is needed.
JOURNAL OF DENTISTRY
(2022)
Article
Dentistry, Oral Surgery & Medicine
E. O. Beltran, J. T. Newton, V Avila, N. B. Pitts, J. E. Castellanos, L. M. A. Tenuta, S. Martignon
Summary: This study explored the challenges of implementing COVID-19 related biosafety measures and personal protective equipment (PPE) from the perspectives of dental practitioners in different countries. The findings indicate that dental practitioners rely on various factors to determine the feasibility and implementation of PPE in their local practices in the absence of a unified guidance document.
JDR CLINICAL & TRANSLATIONAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Lorena Lucia Costa Ladeira, Gustavo. G. G. Nascimento, Fabio Renato Manzolli Leite, Silas Alves-Costa, Erika Barbara Abreu Fonseca Thomaz, Claudia Maria Coelho Alves, Jaime Aparecido Cury, Cecilia Claudia Costa Ribeiro
Summary: This study examined the association between sugar intake above recommended limits and the risk of noncommunicable diseases and chronic oral disease burden in adolescents. The findings indicate that high sugar consumption is associated with a heavier burden of chronic oral diseases.
Article
Dentistry, Oral Surgery & Medicine
Constanza E. Fernandez, Ana Carolina S. Brandao, Eloa C. Bicego-Pereira, Altair A. Del Bel Cury, Jaime A. Cury, Livia M. A. Tenuta
Summary: The effects of pH and titratable acidity on tooth erosion were investigated. The results showed that exposure to solutions with lower pH values caused a decrease in salivary pH, while solutions with higher titratable acidities prolonged the pH recovery time. For teeth, solutions with lower pH values and higher titratable acidities resulted in more severe early erosion.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Public, Environmental & Occupational Health
Mayara Costa Carneiro Ramos, Maria Augusta Bessa Rebelo, Janete Maria Rebelo Vieira, Luis Fernando Bandeira Miranda, Cinthia Pereira Machado Tabchoury, Jaime Aparecido Cury
Summary: This study found problems with the quantity and quality of fluoride in toothpastes distributed by the Manaus primary health care clinics, indicating the need for monitoring these products and urgent revision of the relevant regulations.
REVISTA DE SAUDE PUBLICA
(2022)
Review
Dentistry, Oral Surgery & Medicine
Carlos Alberto Feldens, Liana L. Pinheiro, Jaime A. Cury, Flavia Mendonca, Mario Groisman, Rafael A. H. Costa, Henrique C. Pereira, Alexandre R. Vieira
Summary: Excessive sugar consumption is the main cause of dental caries, which also negatively affects the quality of life. Furthermore, sugar consumption is associated with other noncommunicable diseases. To address this issue, actions at the individual and population levels, such as limiting sugar intake, regulating food labels and advertisements, and taxing sugary products, are needed.
FRONTIERS IN ORAL HEALTH
(2022)
Article
Dentistry, Oral Surgery & Medicine
L. M. A. Tenuta, C. Canady, R. M. Eber, L. Johnson
Summary: The study revealed a lack of agreement between medications reported in medical and dental records, highlighting the need for unified health records and technology to enhance accurate medication reporting.
JDR CLINICAL & TRANSLATIONAL RESEARCH
(2022)