Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study

The Role of Shear-Induced Transforming Growth Factor-β Signaling in the Endothelium

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Defining a therapeutic window for the novel TGF-β inhibitor LY2157299 monohydrate based on a pharmacokinetic/pharmacodynamic model

(2013) Ivelina Gueorguieva et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

High-sensitivity C-reactive protein (hs-CRP) as a biomarker for trastuzumab-induced cardiotoxicity in HER2-positive early-stage breast cancer: a pilot study

(2012) Adedayo A. Onitilo et al.   BREAST CANCER RESEARCH AND TREATMENT

Underestimating Cardiac Toxicity in Cancer Trials: Lessons Learned?

(2012) Ronald M. Witteles et al.   JOURNAL OF CLINICAL ONCOLOGY

Cardiovascular Status of Childhood Cancer Survivors Exposed and Unexposed to Cardiotoxic Therapy

(2012) Steven E. Lipshultz et al.   JOURNAL OF CLINICAL ONCOLOGY

ACCF 2012 Expert Consensus Document on Practical Clinical Considerations in the Interpretation of Troponin Elevations

(2012) L. Kristin Newby et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Oral Administration of GW788388, an Inhibitor of Transforming Growth Factor Beta Signaling, Prevents Heart Fibrosis in Chagas Disease

(2012) Fabiane L. de Oliveira et al.   PLoS Neglected Tropical Diseases

Transforming growth factor beta signaling in adult cardiovascular diseases and repair

(2011) Thomas Doetschman et al.   CELL AND TISSUE RESEARCH

Congestive Heart Failure Risk in Patients With Breast Cancer Treated With Bevacizumab

(2011) Toni K. Choueiri et al.   JOURNAL OF CLINICAL ONCOLOGY

Induction of Heart Valve Lesions by Small-Molecule ALK5 Inhibitors

(2011) Mark J. Anderton et al.   TOXICOLOGIC PATHOLOGY

2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the Diagnosis and Management of Patients With Thoracic Aortic Disease: Executive Summary

(2010) et al.   CIRCULATION

Troponin I As a Predictor for Trastuzumab-Related Cardiotoxicity: Current Data Do Not Provide Mechanistic Insights or Allow for Incorporation Into Clinical Practice

(2010) Shom Goel et al.   JOURNAL OF CLINICAL ONCOLOGY

Signaling via the Tgf-β type I receptor Alk5 in heart development

(2008) Somyoth Sridurongrit et al.   DEVELOPMENTAL BIOLOGY

Transforming Growth Factor-β Signaling in Thoracic Aortic Aneurysm Development: A Paradox in Pathogenesis

(2008) Jeffrey A. Jones et al.   JOURNAL OF VASCULAR RESEARCH