SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation

Nav1.8 channels in ganglionated plexi modulate atrial fibrillation inducibility

(2014) Baozhen Qi et al.   CARDIOVASCULAR RESEARCH

A common genetic variant within SCN10A modulates cardiac SCN5A expression

(2014) Malou van den Boogaard et al.   JOURNAL OF CLINICAL INVESTIGATION

Whole-Exome Sequencing of 2,000 Danish Individuals and the Role of Rare Coding Variants in Type 2 Diabetes

(2013) Kirk E. Lohmueller et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

(2013) Connie R Bezzina et al.   NATURE GENETICS

Genetic mechanisms of atrial fibrillation: impact on response to treatment

(2013) Dawood Darbar et al.   Nature Reviews Cardiology

Blocking Scn10a Channels in Heart Reduces Late Sodium Current and Is Antiarrhythmic

(2012) Tao Yang et al.   CIRCULATION RESEARCH

Functional Na V 1.8 Channels in Intracardiac Neurons

(2012) Arie O. Verkerk et al.   CIRCULATION RESEARCH

Evaluating Pathogenicity of Rare Variants From Dilated Cardiomyopathy in the Exome Era

(2012) Nadine Norton et al.   Circulation-Cardiovascular Genetics

Expression, Purification and Functional Reconstitution of Slack Sodium-Activated Potassium Channels

(2012) Yangyang Yan et al.   JOURNAL OF MEMBRANE BIOLOGY

Chromosome 4q25 Variants Are Genetic Modifiers of Rare Ion Channel Mutations Associated With Familial Atrial Fibrillation

(2012) Marylyn D. Ritchie et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Epistatic Effects of Potassium Channel Variation on Cardiac Repolarization and Atrial Fibrillation Risk

(2012) Stefan A. Mann et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Localisation of SCN10A Gene Product Nav1.8 and Novel Pain-Related Ion Channels in Human Heart

(2011) Paul Facer et al.   International Heart Journal

Identification of Genomic Predictors of Atrioventricular Conduction

(2010) Joshua C. Denny et al.   CIRCULATION

Several common variants modulate heart rate, PR interval and QRS duration

(2010) Hilma Holm et al.   NATURE GENETICS

Genome-wide association study of PR interval

(2010) Arne Pfeufer et al.   NATURE GENETICS

Genetic variation in SCN10A influences cardiac conduction

(2010) John C Chambers et al.   NATURE GENETICS

Mutations in Sodium Channel β1- and β2-Subunits Associated With Atrial Fibrillation

(2009) Hiroshi Watanabe et al.   Circulation-Arrhythmia and Electrophysiology

Variation in the 4q25 Chromosomal Locus Predicts Atrial Fibrillation After Coronary Artery Bypass Graft Surgery

(2009) Simon C. Body et al.   Circulation-Cardiovascular Genetics

Is it time to develop a “pathogenicity” score to distinguish long QT syndrome causing mutations from “background” genetic noise?

(2009) Dawood Darbar   HEART RHYTHM

Long-term Outcomes in Individuals With Prolonged PR Interval or First-Degree Atrioventricular Block

(2009) Susan Cheng   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Structural Determinants of Drugs Acting on the Nav1.8 Channel

(2009) Liam E. Browne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac Sodium Channel ( SCN5A ) Variants Associated with Atrial Fibrillation

(2008) Dawood Darbar et al.   CIRCULATION