Reversibility of T-tubule remodelling in heart failure: mechanical load as a dynamic regulator of the T-tubules

Subcellular Structures and Function of Myocytes Impaired During Heart Failure Are Restored by Cardiac Resynchronization Therapy

(2012) Frank B. Sachse et al.   CIRCULATION RESEARCH

Mir-24 Regulates Junctophilin-2 Expression in Cardiomyocytes

(2012) Ming Xu et al.   CIRCULATION RESEARCH

Stimulated Emission Depletion Live-Cell Super-Resolution Imaging Shows Proliferative Remodeling of T-Tubule Membrane Structures After Myocardial Infarction

(2012) Eva Wagner et al.   CIRCULATION RESEARCH

Plasticity of Surface Structures and β 2 -Adrenergic Receptor Localization in Failing Ventricular Cardiomyocytes During Recovery From Heart Failure

(2012) Alexander R. Lyon et al.   Circulation-Heart Failure

Mechanical unloading and cell therapy have a synergistic role in the recovery and regeneration of the failing heart

(2012) M. Ibrahim et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Mechanical unloading reverses transverse tubule remodelling and normalizes local Ca2+-induced Ca2+release in a rodent model of heart failure

(2012) Michael Ibrahim et al.   EUROPEAN JOURNAL OF HEART FAILURE

β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction

(2012) Biyi Chen et al.   FASEB JOURNAL

A critical role for Telethonin in regulating t-tubule structure and function in the mammalian heart

(2012) M. Ibrahim et al.   HUMAN MOLECULAR GENETICS

Cardiomyocyte Ca2+handling and structure is regulated by degree and duration of mechanical load variation

(2012) Michael Ibrahim et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Heterotopic abdominal heart transplantation in rats for functional studies of ventricular unloading

(2012) Michael Ibrahim et al.   JOURNAL OF SURGICAL RESEARCH

Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout

(2012) F. Swift et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bridge to Recovery: What Remains to be Discovered?

(2011) Michael Ibrahim et al.   CARDIOLOGY CLINICS

Taking pressure off the heart: the ins and outs of atrophic remodelling

(2011) K. K. Baskin et al.   CARDIOVASCULAR RESEARCH

Disrupted Junctional Membrane Complexes and Hyperactive Ryanodine Receptors After Acute Junctophilin Knockdown in Mice

(2011) Ralph J. van Oort et al.   CIRCULATION

Reversal of Severe Heart Failure With a Continuous-Flow Left Ventricular Assist Device and Pharmacological Therapy

(2011) Emma J. Birks et al.   CIRCULATION

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes

(2011) Ting-Ting Hong et al.   HEART RHYTHM

Sildenafil Prevents and Reverses Transverse-Tubule Remodeling and Ca 2+ Handling Dysfunction in Right Ventricle Failure Induced by Pulmonary Artery Hypertension

(2011) Yu-Ping Xie et al.   HYPERTENSION

Subcellular Heterogeneity of Ryanodine Receptor Properties in Ventricular Myocytes with Low T-Tubule Density

(2011) Liesbeth Biesmans et al.   PLoS One

The structure and function of cardiac t-tubules in health and disease

(2011) M. Ibrahim et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Differential Cardiac Remodeling in Preload Versus Afterload

(2010) Karl Toischer et al.   CIRCULATION

T-Tubule Remodeling During Transition From Hypertrophy to Heart Failure

(2010) Sheng Wei et al.   CIRCULATION RESEARCH

Prolonged mechanical unloading affects cardiomyocyte excitation-contraction coupling, transverse-tubule structure, and the cell surface

(2010) Michael Ibrahim et al.   FASEB JOURNAL

There Goes the Neighborhood: Pathological Alterations in T-Tubule Morphology and Consequences for Cardiomyocyte Handling

(2010) William E. Louch et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Low-intensity electrical stimulation ameliorates disruption of transverse tubules and neuromuscular junctional architecture in denervated rat skeletal muscle fibers

(2010) Kounosuke Tomori et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

 2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

(2010) V. O. Nikolaev et al.   SCIENCE

BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

(2010) Ting-Ting Hong et al.   PLOS BIOLOGY

Interval Training Normalizes Cardiomyocyte Function, Diastolic Ca 2+ Control, and SR Ca 2+ Release Synchronicity in a Mouse Model of Diabetic Cardiomyopathy

(2009) Tomas O. Stølen et al.   CIRCULATION RESEARCH

The role of mammalian cardiac t-tubules in excitation-contraction coupling: experimental and computational approaches

(2009) Clive H. Orchard et al.   EXPERIMENTAL PHYSIOLOGY

Depletion of zebrafish Tcap leads to muscular dystrophy via disrupting sarcomere–membrane interaction, not sarcomere assembly

(2009) Ruilin Zhang et al.   HUMAN MOLECULAR GENETICS

Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart

(2009) A. R. Lyon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Integration of Ca2+-Calmodulin Signal in Intact Ventricular Myocytes at Low and High Affinity Ca2+-Calmodulin Targets

(2008) Qiujing Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prolonged Mechanical Unloading Reduces Myofilament Sensitivity to Calcium and Sarcoplasmic Reticulum Calcium Uptake Leading to Contractile Dysfunction

(2008) Gopal K.R. Soppa et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Remodeling of T-Tubules and Reduced Synchrony of Ca 2+ Release in Myocytes From Chronically Ischemic Myocardium

(2007) Frank R. Heinzel et al.   CIRCULATION RESEARCH