Apelin protects sarcoplasmic reticulum function and cardiac performance in ischaemia-reperfusion by attenuating oxidation of sarcoplasmic reticulum Ca2+-ATPase and ryanodine receptor
出版年份 2013 全文链接
标题
Apelin protects sarcoplasmic reticulum function and cardiac performance in ischaemia-reperfusion by attenuating oxidation of sarcoplasmic reticulum Ca2+-ATPase and ryanodine receptor
作者
关键词
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出版物
CARDIOVASCULAR RESEARCH
Volume 100, Issue 1, Pages 114-124
出版商
Oxford University Press (OUP)
发表日期
2013-06-15
DOI
10.1093/cvr/cvt160
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- Apelin-13 protects the heart against ischemia-reperfusion injury through inhibition of ER-dependent apoptotic pathways in a time-dependent fashion
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- Apelin-13 limits infarct size and improves cardiac postischemic mechanical recovery only if given after ischemia
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- Ca2+ wave probability is determined by the balance between SERCA2-dependent Ca2+ reuptake and threshold SR Ca2+ content
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- Polyol pathway impairs the function of SERCA and RyR in ischemic-reperfused rat hearts by increasing oxidative modifications of these proteins
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- Apelin protects heart against ischemia/reperfusion injury in rat
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- Loss of ischaemic preconditioning in ovariectomized rat hearts: possible involvement of impaired protein kinase C phosphorylation
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- The paradigm of postconditioning to protect the heart
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- Apelin reduces myocardial reperfusion injury independently of PI3K/Akt and P70S6 kinase
- (2007) Matthias J. Kleinz et al. REGULATORY PEPTIDES
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