Spatial control of the βAR system in heart failure: the transverse tubule and beyond

Nanoscale Organization of Junctophilin-2 and Ryanodine Receptors within Peripheral Couplings of Rat Ventricular Cardiomyocytes

(2012) Isuru D. Jayasinghe et al.   BIOPHYSICAL JOURNAL

High Levels of Circulating Epinephrine Trigger Apical Cardiodepression in a β 2 -Adrenergic Receptor/G i –Dependent Manner

(2012) Helen Paur et al.   CIRCULATION

Subcellular Structures and Function of Myocytes Impaired During Heart Failure Are Restored by Cardiac Resynchronization Therapy

(2012) Frank B. Sachse et al.   CIRCULATION RESEARCH

Stimulated Emission Depletion Live-Cell Super-Resolution Imaging Shows Proliferative Remodeling of T-Tubule Membrane Structures After Myocardial Infarction

(2012) Eva Wagner et al.   CIRCULATION RESEARCH

Plasticity of Surface Structures and β 2 -Adrenergic Receptor Localization in Failing Ventricular Cardiomyocytes During Recovery From Heart Failure

(2012) Alexander R. Lyon et al.   Circulation-Heart Failure

Mechanical unloading reverses transverse tubule remodelling and normalizes local Ca2+-induced Ca2+release in a rodent model of heart failure

(2012) Michael Ibrahim et al.   EUROPEAN JOURNAL OF HEART FAILURE

β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction

(2012) Biyi Chen et al.   FASEB JOURNAL

Cardiomyocyte Ca2+handling and structure is regulated by degree and duration of mechanical load variation

(2012) Michael Ibrahim et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Profiling of cAMP and cGMP phosphodiesterases in isolated ventricular cardiomyocytes from human hearts: Comparison with rat and guinea pig

(2012) W.B. Johnson et al.   LIFE SCIENCES

Telethonin Deficiency Is Associated With Maladaptation to Biomechanical Stress in the Mammalian Heart

(2011) Ralph Knöll et al.   CIRCULATION RESEARCH

Junctophilin-2 Expression Silencing Causes Cardiocyte Hypertrophy and Abnormal Intracellular Calcium-Handling

(2011) Andrew P. Landstrom et al.   Circulation-Heart Failure

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes

(2011) Ting-Ting Hong et al.   HEART RHYTHM

Sildenafil Prevents and Reverses Transverse-Tubule Remodeling and Ca 2+ Handling Dysfunction in Right Ventricle Failure Induced by Pulmonary Artery Hypertension

(2011) Yu-Ping Xie et al.   HYPERTENSION

Myocardial G Protein Receptor–Coupled Kinase Expression Correlates With Functional Parameters and Clinical Severity in Advanced Heart Failure

(2011) Jaime Agüero et al.   JOURNAL OF CARDIAC FAILURE

Phosphodiesterase 4B in the cardiac L-type Ca2+ channel complex regulates Ca2+ current and protects against ventricular arrhythmias in mice

(2011) Jérôme Leroy et al.   JOURNAL OF CLINICAL INVESTIGATION

Reorganized PKA-AKAP associations in the failing human heart

(2011) Thin-Thin Aye et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Caveolae compartmentalise β2-adrenoceptor signals by curtailing cAMP production and maintaining phosphatase activity in the sarcoplasmic reticulum of the adult ventricular myocyte

(2011) David A. MacDougall et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Conserved expression and functions of PDE4 in rodent and human heart

(2010) Wito Richter et al.   BASIC RESEARCH IN CARDIOLOGY

Altered Spatiotemporal Dynamics of the Mitochondrial Membrane Potential in the Hypertrophied Heart

(2010) Hongwei Jin et al.   BIOPHYSICAL JOURNAL

T-Tubule Remodeling During Transition From Hypertrophy to Heart Failure

(2010) Sheng Wei et al.   CIRCULATION RESEARCH

Sympathetic Stimulation of Adult Cardiomyocytes Requires Association of AKAP5 With a Subpopulation of L-Type Calcium Channels

(2010) C. Blake Nichols et al.   CIRCULATION RESEARCH

The proposed functions of membrane curvatures mediated by the BAR domain superfamily proteins

(2010) S. Suetsugu   JOURNAL OF BIOCHEMISTRY

Mechanisms of stress (Takotsubo) cardiomyopathy

(2010) Holger M. Nef et al.   Nature Reviews Cardiology

 2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

(2010) V. O. Nikolaev et al.   SCIENCE

BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

(2010) Ting-Ting Hong et al.   PLOS BIOLOGY

Mechanisms of Enhanced β-Adrenergic Reserve From Cardiac Resynchronization Therapy

(2009) Khalid Chakir et al.   CIRCULATION

Iatrogenic epinephrine-induced reverse Takotsubo cardiomyopathy: direct evidence supporting the role of catecholamines in the pathophysiology of the “broken heart syndrome”

(2009) Ivan V. Litvinov et al.   Clinical Research in Cardiology

Depletion of zebrafish Tcap leads to muscular dystrophy via disrupting sarcomere–membrane interaction, not sarcomere assembly

(2009) Ruilin Zhang et al.   HUMAN MOLECULAR GENETICS

Excitation–contraction coupling changes during postnatal cardiac development

(2009) Andrew P. Ziman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nanoscale live-cell imaging using hopping probe ion conductance microscopy

(2009) Pavel Novak et al.   NATURE METHODS

Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart

(2009) A. R. Lyon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles

(2008) F Afzal et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protein Kinase A Type I and Type II Define Distinct Intracellular Signaling Compartments

(2008) Giulietta Di Benedetto et al.   CIRCULATION RESEARCH

Remodeling of T-Tubules and Reduced Synchrony of Ca 2+ Release in Myocytes From Chronically Ischemic Myocardium

(2007) Frank R. Heinzel et al.   CIRCULATION RESEARCH

Stress (Takotsubo) cardiomyopathy—a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning

(2007) Alexander R Lyon et al.   Nature clinical practice. Cardiovascular medicine