In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling

Disease Pathways and Novel Therapeutic Targets in Hypertrophic Cardiomyopathy

(2011) Houman Ashrafian et al.   CIRCULATION RESEARCH

Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish

(2011) J. R. Becker et al.   Disease Models & Mechanisms

MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1L613V mutation

(2011) Xue Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Systematizing Serendipity for Cardiovascular Drug Discovery

(2009) Peter J. Schlueter et al.   CIRCULATION

Heart Disease and Stroke Statistics—2009 Update

(2009) et al.   CIRCULATION

Cardiac hypertrophy: Targeting Raf/MEK/ERK1/2-signaling

(2009) Kristina Lorenz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Distinct Regulation of Developmental and Heart Disease–Induced Atrial Natriuretic Factor Expression by Two Separate Distal Sequences

(2008) Thomas Horsthuis et al.   CIRCULATION RESEARCH