Late Sodium Current Inhibition in Acquired and Inherited Ventricular (dys)function and Arrhythmias
出版年份 2013 全文链接
标题
Late Sodium Current Inhibition in Acquired and Inherited Ventricular (dys)function and Arrhythmias
作者
关键词
Late sodium current, Pharmacology, Myocardial ischemia, Heart failure, Arrhythmias, Long QT syndrome
出版物
CARDIOVASCULAR DRUGS AND THERAPY
Volume 27, Issue 1, Pages 91-101
出版商
Springer Nature
发表日期
2013-01-05
DOI
10.1007/s10557-012-6433-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ranolazine Improves Cardiac Diastolic Dysfunction Through Modulation of Myofilament Calcium Sensitivity
- (2012) Joshua D. Lovelock et al. CIRCULATION RESEARCH
- Pharmacological treatment options for hypertrophic cardiomyopathy: high time for evidence
- (2012) Roberto Spoladore et al. EUROPEAN HEART JOURNAL
- Mechanisms of atrial-selective block of Na+ channels by ranolazine: I. Experimental analysis of the use-dependent block
- (2011) Andrew C. Zygmunt et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Ranolazine for the Treatment of Heart Failure With Preserved Ejection Fraction: Background, Aims, and Design of the RALI-DHF Study
- (2011) Claudius Jacobshagen et al. CLINICAL CARDIOLOGY
- Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations
- (2011) Tamás Szél et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Electrophysiologic basis for the antiarrhythmic actions of ranolazine
- (2011) Charles Antzelevitch et al. HEART RHYTHM
- Pathophysiology of the cardiac late Na current and its potential as a drug target
- (2011) Jonathan D. Moreno et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Suppression of Re-Entrant and Multifocal Ventricular Fibrillation by the Late Sodium Current Blocker Ranolazine
- (2011) Norishige Morita et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Ranolazine Reduces Ventricular Tachycardia Burden and ICD Shocks in Patients with Drug-Refractory ICD Shocks
- (2011) T. JARED BUNCH et al. PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
- Ranolazine reduces Ca2+ overload and oxidative stress and improves mitochondrial integrity to protect against ischemia reperfusion injury in isolated hearts
- (2011) Mohammed Aldakkak et al. PHARMACOLOGICAL RESEARCH
- Role of ranolazine in angina, heart failure, arrhythmias, and diabetes
- (2011) Samuel Sossalla et al. PHARMACOLOGY & THERAPEUTICS
- Diastolic dysfunction and arrhythmias caused by overexpression of CaMKIIδC can be reversed by inhibition of late Na+ current
- (2010) Samuel Sossalla et al. BASIC RESEARCH IN CARDIOLOGY
- Predicting drug-induced slowing of conduction and pro-arrhythmia: identifying the ‘bad’ sodium current blockers
- (2010) Hua Rong Lu et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Antianginal Agent Ranolazine is a Potent Antiarrhythmic Agent that Reduces Ventricular Arrhythmias: Through a Mechanism Favoring Inhibition of Late Sodium Channel
- (2010) Robert A. Kloner et al. Cardiovascular Therapeutics
- REVIEW: Sodium Channel (Dys)Function and Cardiac Arrhythmias
- (2010) Carol Ann Remme et al. Cardiovascular Therapeutics
- Antifibrillatory effect of ranolazine during severe coronary stenosis in the intact porcine model
- (2010) Tuomo Nieminen et al. HEART RHYTHM
- Improvement in Left Ventricular Systolic and Diastolic Performance During Ranolazine Treatment in Patients With Stable Angina
- (2010) Vincent M. Figueredo et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS
- Late sodium current contributes to diastolic cell Ca2+ accumulation in chronic heart failure
- (2010) Nidas A. Undrovinas et al. Journal of Physiological Sciences
- Late Na+Current Inhibition by Ranolazine Reduces Torsades de Pointes in the Chronic Atrioventricular Block Dog Model
- (2010) Gudrun Antoons et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Ranolazine-Treatment of Ventricular Tachycardia and Symptomatic Ventricular Premature Beats in Ischemic Cardiomyopathy
- (2010) SUDIP NANDA et al. PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
- Flecainide-Associated Bradycardia-Dependent Torsade de Pointes: Another Potential Mechanism of Proarrhythmia
- (2010) HAN SANG KIM et al. PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
- Ranolazine Safely Decreases Ventricular and Atrial Fibrillation in Timothy Syndrome (LQT8)
- (2010) DIPAK P. SHAH et al. PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
- Ranolazine, an antianginal agent, markedly reduces ventricular arrhythmias induced by ischemia and ischemia-reperfusion
- (2009) Arvinder K. Dhalla et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Increased late sodium currents are related to transcription of neuronal isoforms in a pressure-overload model
- (2009) Yutao Xi et al. EUROPEAN JOURNAL OF HEART FAILURE
- Rapid Kinetic Interactions of Ranolazine With HERG K+ Current
- (2009) Sridharan Rajamani et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- A Novel Mechanism for the Treatment of Angina, Arrhythmias, and Diastolic Dysfunction: Inhibition of Late INa Using Ranolazine
- (2009) Lars S Maier JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Diastolic transient inward current in long QT syndrome type 3 is caused by Ca2+ overload and inhibited by ranolazine
- (2009) N. Lindegger et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Sinus node dysfunction in ATX-II-induced in-vitro murine model of long QT3 syndrome and rescue effect of ranolazine
- (2009) Jingjing Wu et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Modulation of late sodium current by Ca2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences
- (2008) Victor A. Maltsev et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes
- (2008) Yejia Song et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure
- (2008) Sharad Rastogi et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Ranolazine Shortens Repolarization in Patients with Sustained Inward Sodium Current Due to Type-3 Long-QT Syndrome
- (2008) ARTHUR J. MOSS et al. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
- Ranolazine Inhibits An Oxidative Stress-induced Increase in Myocyte Sodium and Calcium Loading During Simulated-demand Ischemia
- (2008) Xiu Q Zhang et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts — Role of late sodium current and intracellular ion accumulation
- (2008) Samuel Sossalla et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Late sodium current inhibition as a new cardioprotective approach
- (2008) Sharon L. Hale et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Ranolozine-Induced Suppression of Ventricular Tachycardia in a Patient with Nonischemic Cardiomyopathy: A Case Report
- (2008) DAVID K. MURDOCK et al. PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
- Pathophysiology and pharmacology of the cardiac “late sodium current”
- (2008) Antonio Zaza et al. PHARMACOLOGY & THERAPEUTICS
- Cardiac Sodium Channel Overlap Syndromes: Different Faces of SCN5A Mutations
- (2008) Carol Ann Remme et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Calcium Cycling and Signaling in Cardiac Myocytes
- (2007) Donald M. Bers Annual Review of Physiology
- The cardiac persistent sodium current: an appealing therapeutic target?
- (2007) D A Saint BRITISH JOURNAL OF PHARMACOLOGY
- Late sodium current in failing heart: Friend or foe?
- (2007) Victor A. Maltsev et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Molecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of action
- (2006) Sandra Fredj et al. BRITISH JOURNAL OF PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More