Article
Medicine, General & Internal
Jamal S. Rana, Salim S. Virani, Howard H. Moffet, Jennifer Y. Liu, Landis A. Coghlan, Jitesh Vasadia, Christie M. Ballantyne, Andrew J. Karter
Summary: The study aimed to evaluate the association between outpatient LDL-C testing and subsequent statin adherence and intensification in patients after an ASCVD event. The results showed that LDL-C testing was associated with improved statin adherence and higher rates of treatment intensification.
AMERICAN JOURNAL OF MEDICINE
(2022)
Article
Pharmacology & Pharmacy
Stella Trompet, Iris Postmus, Helen R. Warren, Raymond Noordam, Roelof A. J. Smit, Elizabeth Theusch, Xiaohui Li, Benoit Arsenault, Daniel I. Chasman, Graham A. Hitman, Patricia B. Munroe, Jerome I. Rotter, Bruce M. Psaty, Mark J. Caulfield, Ron M. Krauss, Adrienne L. Cupples, Wouter J. Jukema
Summary: The pharmacogenetic effect of genetic variation on cardiovascular disease risk reduction in response to statin treatment was investigated through a genome-wide association study (GWAS). The results showed that genetic variation did not significantly affect the response of statins on cardiovascular risk reduction. This suggests that genetic testing for predicting the effects of statins on clinical events may not be a useful tool in clinical practice.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Michel Farnier, Raul D. Santos, Juan Cosin-Sales, Marat Ezhov, Jian Liu, Denis Granados, Serena Santoni, Irfan Khan, Alberico L. Catapano
Summary: According to the 2019 ESC/EAS guidelines, the use of statin, ezetimibe, and statin plus ezetimibe FDC treatment strategies can significantly reduce the incidence of major adverse cardiovascular events at the population level.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Ju Hyeon Kim, Jung-Joon Cha, Subin Lim, Jungseok An, Mi-Na Kim, Soon Jun Hong, Hyung Joon Joo, Jae Hyoung Park, Cheol Woong Yu, Do-Sun Lim, Kyeongmin Byeon, Sang-Wook Kim, Eun-Seok Shin, Kwang Soo Cha, Jei Keon Chae, Youngkeun Ahn, Myung Ho Jeong, Tae Hoon Ahn
Summary: This study aimed to investigate recurrent adverse events in post-myocardial infarction patients. The results showed that achieving target LDL-C levels in acute myocardial infarction patients was associated with a lower incidence and reduced hazard of recurrent clinical events, highlighting the need to improve LDL-C level management in real-world settings.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
Jiongchao Guo, Min Chen, Yu Hong, Yating Huang, Haiyan Zhang, Yuan Zhou, Bingfeng Zhou, Minmin Fu
Summary: This study found that the neutrophil to high-density lipoprotein cholesterol ratio (NHR) has potential clinical utility as a predictive indicator in ST-segment elevation myocardial infarction (STEMI) patients after percutaneous coronary intervention (PCI) during hospitalization, both for major adverse cardiovascular events (MACE) and the degree of coronary artery stenosis.
JOURNAL OF INFLAMMATION RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Yu Yang, Jian Zhang, Lin Jia, Jiannan Su, Mengqing Ma, Xianhe Lin
Summary: This study investigated the impact of the interaction between uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) on the prognosis of patients with acute myocardial infarction (AMI). The results showed a positive additive interaction between UA and HDL-C for major adverse cardiovascular events (MACE), and the UA and HDL-C ratio (UHR) was found to be an independent prognostic indicator.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Biology
E. T. Figueiredo, C. H. Miranda
Summary: This study aimed to evaluate whether the monocyte to high-density lipoprotein cholesterol ratio (MHR) variation is a predictor of major adverse cardiovascular events (MACE) after acute coronary syndrome (ACS). The results showed that the MHR variation is an independent predictor of MACE after ACS, suggesting it as a potential marker for residual cardiovascular risk.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
(2022)
Article
Multidisciplinary Sciences
Shan Li, Wei Zhang, Hongbin Liu
Summary: This study evaluated the association between lipid levels and mortality in critically ill patients. A J-shaped association was observed between LDL-C, HDL-C, and TC levels and all-cause and cause-specific mortality, with low concentrations associated with higher risk. Low LDL-C combined with low HDL-C had a marked synergistic effect on the risk of mortality.
SCIENTIFIC REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Swati Sakhuja, Vera A. Bittner, Todd M. Brown, Michael E. Farkouh, Emily B. Levitan, Monika M. Safford, Mark Woodward, Ligong Chen, Ruoyan Sun, Nafeesa Dhalwani, Jenna Jones, Bethany Kalich, Jason Exter, Paul Muntner, Robert S. Rosenson, Lisandro D. Colantonio
Summary: Implementing guideline-recommended cholesterol-lowering therapy could prevent a significant percentage of recurrent ASCVD events.
CARDIOVASCULAR DRUGS AND THERAPY
(2023)
Article
Medicine, General & Internal
Hiroko Inoue, Yuhei Shiga, Kenji Norimatsu, Kohei Tashiro, Makito Futami, Yasunori Suematsu, Makoto Sugihara, Hiroaki Nishikawa, Yousuke Katsuda, Shin-ichiro Miura
Summary: The study found that in addition to HDL-C, total CEC was associated with the presence of MACE, while %CEC and HDL functionality were not associated with MACE.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Peripheral Vascular Disease
Huan Hu, Ami Fukunaga, Toshitaka Yokoya, Tohru Nakagawa, Toru Honda, Shuichiro Yamamoto, Hiroko Okazaki, Toshiaki Miyamoto, Naoko Sasaki, Takayuki Ogasawara, Naoki Gonmori, Kenya Yamamoto, Ai Hori, Kentaro Tomita, Satsue Nagahama, Maki Konishi, Nobumi Katayama, Hisayoshi Morioka, Isamu Kabe, Tetsuya Mizoue, Seitaro Dohi
Summary: The study found an association between non-high-density lipoprotein cholesterol (non-HDL-C) levels and the risk of cardiovascular disease (CVD) and its subtypes. Elevated non-HDL-C levels were associated with an increased risk of myocardial infarction, while both high and low non-HDL-C levels were associated with a higher risk of stroke and its subtypes.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2022)
Article
Biology
Ziv Dadon, Mady Moriel, Zaza Iakobishvili, Elad Asher, Tal Y. Samuel, Dov Gavish, Michael Glikson, Shmuel Gottlieb
Summary: Among patients admitted with ACS, pretreatment with high-intensity statin therapy was independently associated with a lower probability of STEMI presentation, while low-intensity statin therapy and LDL-C < 70 mg/dL were not.
Article
Multidisciplinary Sciences
Yu-Cheng Kao, Tien-Hsing Chen, Chi-Hung Liu, Jawl-Shan Hwang, Ching-Chung Hsiao, Yu-Sheng Lin, Chun-Tai Mao, Ming-Jui Hung, Yan-Rong Li
Summary: In patients with type 2 diabetes mellitus, the study found that Atorvastatin 40 mg and ezetimibe 10 mg/simvastatin 20 mg had similar reductions of low-density lipoprotein cholesterol and major cardiovascular outcomes. However, the Atorvastatin 40 group had lower risks of unstable angina, percutaneous coronary intervention, and coronary artery bypass grafting compared to the ezetimibe/simvastatin group. This suggests that the main driver for cardiovascular risk reductions is still LDL-C lowering.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Yang Chen, Congcong Ding, Longlong Hu, Yuehua Ruan, Kai Zou, Cong Dai, Yanhui Liao, Hanhui Liao, Yi Xia, Yuanbin Zhao, Renqiang Yang
Summary: The study found that in Chinese patients with first AMI, higher baseline SUA was positively associated with higher LDL-C deduction percentage and higher rate of LDL-C control in the short-term follow-up. Baseline SUA may be profitable in predicting the risk stratification of uncontrolled LDL-C and dyslipidemia management.
BMC CARDIOVASCULAR DISORDERS
(2021)
Article
Cardiac & Cardiovascular Systems
Rafael Diaz, Qian H. Li, Deepak L. Bhatt, Vera A. Bittner, Marie T. Baccara-Dinet, Shaun G. Goodman, J. Wouter Jukema, Takeshi Kimura, Alexander Parkhomenko, Robert Pordy, Zeljko Reiner, Matthew T. Roe, Michael Szarek, Hung-Fat Tse, Harvey D. White, Doron Zahger, Andreas M. Zeiher, Gregory G. Schwartz, Ph Gabriel Steg
Summary: The study investigated the effects of PCSK9 inhibitor alirocumab on major adverse cardiovascular events in patients with acute coronary syndrome under different intensity of background statin treatment. Alirocumab was found to reduce the relative risk of major adverse cardiovascular events, especially in patients not receiving statin therapy.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Namkyun Kim, Jang Hoon Lee, Se Yong Jang, Myung Hwan, Dong Heon Yang, Hun Sik Park, Yongkeun Cho, Myung Ho Jeong, Jong-Seon Park, Hyo-Soo Kim, Seung-Ho Hur, In-Whan Seong, Myeong-Chan Cho, Chong-Jin Kim, Shung Chull Chae
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2020)
Article
Peripheral Vascular Disease
Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seunghwan Kim, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
Article
Cardiac & Cardiovascular Systems
Jeong Cheon Choe, Kwang Soo Cha, Jeong Gyu Lee, Jinmi Kim, Ji Yeon Shin, Jinhee Ahn, Jin Sup Park, Hye Won Lee, Jun-Hyok Oh, Jung Hyun Choi, Han Cheol Lee, Taek Jong Hong, Myung Ho Jeong
JACC-CARDIOVASCULAR INTERVENTIONS
(2020)
Article
Clinical Neurology
Jae-Min Kim, Robert Stewart, Ju-Wan Kim, Hee-Ju Kang, Sung-Wan Kim, Il-Seon Shin, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Jin-Sang Yoon
JOURNAL OF AFFECTIVE DISORDERS
(2020)
Article
Cardiac & Cardiovascular Systems
Joon Ho Ahn, Youngkeun Ahn, Myung Ho Jeong, Ju Han Kim, Young Joon Hong, Doo Sun Sim, Min Chul Kim, Jin Yong Hwang, Jung Han Yoon, In Whan Seong, Seung-Ho Hur, Seok Kyu Oh
JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Seung Hun Lee, Hyun Kuk Kim, Joo Myung Lee, Young Joon Hong, Kyung Seob Lim, Han Byul Kim, Ki Hong Choi, Eun-Seok Shin, Chang-Wook Nam, Joon-Hyung Doh, Jeong Hoon Yang, Young Bin Song, Joo-Yong Hahn, Seung-Hyuk Choi, Myung Ho Jeong, Habib Samady, Javier Escaned
JACC-CARDIOVASCULAR INTERVENTIONS
(2020)
Correction
Psychology, Clinical
Jae-Min Kim, Robert Stewart, Hee-Ju Kang, Seon-Young Kim, Ju-Wan Kim, Hee-Joon Lee, Ju-Yeon Lee, Sung-Wan Kim, Il-Seon Shin, Min-Chul Kim, Hee-Young Shin, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Jin-Sang Yoon
PSYCHOLOGICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Hee-Ju Kang, Robert Stewart, Ju-Wan Kim, Sung-Wan Kim, Il-Seon Shin, Min-Chul Kim, Young Joon Hong, Youngkeun Ahn, Myung-Geun Shin, Myung Ho Jeong, Jin-Sang Yoon, Jae-Min Kim
SCIENTIFIC REPORTS
(2020)
Article
Cardiac & Cardiovascular Systems
Han Cheol Lee, Jin Sup Park, Jeong Cheon Choe, Jin Hee Ahn, Hye Won Lee, Jun-Hyok Oh, Jung Hyun Choi, Kwang Soo Cha, Taek Jong Hong, Myung Ho Jeong
AMERICAN JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Min Chul Kim, SungA Bae, Youngkeun Ahn, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Hyo-Soo Kim, Shung Chull Chae, Kwang Soo Cha
Summary: In patients with STEMI and MVD without cardiogenic shock, in-hospital stepwise MVR was associated with a lower risk of all-cause death than culprit-only PCI or immediate MVR, particularly in the high-risk subgroup.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Psychiatry
Ju-Wan Kim, Robert Stewart, Hee-Joon Lee, Hee-Ju Kang, Sung-Wan Kim, Il-Seon Shin, Min-Chul Kim, Young-Joon Hong, Young-Keun Ahn, Myung-Ho Jeong, Jin-Sang Yoon, Jae-Min Kim
GENERAL HOSPITAL PSYCHIATRY
(2020)
Article
Cardiac & Cardiovascular Systems
Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seunghwan Kim, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
INTERNATIONAL HEART JOURNAL
(2020)
Article
Peripheral Vascular Disease
Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seunghwan Kim, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
Summary: In patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD), prediabetes may have a similar impact as diabetes on major clinical outcomes, including an increased risk of all-cause death and cardiovascular events.
Article
Psychiatry
Anna Jo, Honey Kim, Ju-Yeon Lee, Jae-Min Kim, Myung Ho Jeong, Young-Chul Chung, Seok-Joon Sohn, Sung-Wan Kim
Summary: The study found that delayed treatment of first-episode schizophrenia patients was associated with older age, higher clinical symptom scores, higher conscientiousness of patients, and poorer family cohesion. This suggests that family dynamics and patient personality traits play a role in determining timely access to mental health services for patients with early psychotic symptoms.
EARLY INTERVENTION IN PSYCHIATRY
(2021)
Article
Cardiac & Cardiovascular Systems
Jihoon Kim, Joo Myung Lee, Taek Kyu Park, Jeong Hoon Yang, Joo-Yong Hahn, Jin-Ho Choi, Seung-Hyuk Choi, Ki Bae Seung, Seung-Ho Hur, Seung-Woon Rha, June-Hong Kim, Rak Kyeong Choi, Ju Hyeon Oh, Hyo-Soo Kim, Seung-Hwan Lee, Jong-Seon Park, Sung Yun Lee, Dong Woon Jeon, Myung Ho Jeong, Jae-Hwan Lee, Sang Yeub Lee, Woo-Jung Park, Young Bin Song, Hyeon-Cheol Gwon
Summary: For patients with left main bifurcation lesions, conservative and aggressive strategies for provisional side branch intervention have similar 1-year target lesion failure rates.
REVISTA ESPANOLA DE CARDIOLOGIA
(2021)