期刊
CARDIOLOGY IN THE YOUNG
卷 28, 期 10, 页码 1148-1153出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S104795111800118X
关键词
Beta-blocker; CT angiography; Kawasaki disease; children
Background: There is no standard dose or protocol for beta-blocker administration as preconditioning in children undergoing coronary CT angiography. Methods: A total of 63 consecutive patients, with a mean age of 10.0 +/- 3.1 years, who underwent coronary CT angiography to assess possible coronary complications were enrolled in a single-centre, retrospective study. All patients were given an oral beta-blocker 1 hour before coronary CT angiography. Additional oral beta-blocker or intravenous beta-blocker was given to those with a high heart rate. We compared image quality, radiation exposure, and adverse events among the patients without additional beta-blocker, with additional oral beta-blocker, and with additional intravenous beta-blocker. Results: There were no significant differences in image quality or radiation exposure among the groups. The heart rate just before scanning was significantly correlated with image quality (p<0.001, r = -0.533) but was not correlated with radiation exposure (p = 0.45, r = 0.096). There were no adverse events related to any allergic reaction, thereby showing the effectiveness of the beta-blocker. Conclusion: Initial oral beta-blocker administration (0.8 mg/kg/dose) should be administered to all children undergoing coronary CT angiography. Additional intravenous beta-blocker should be given to those with poor heart rate control to improve image quality without increasing radiation exposure or allowing adverse events.
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