Pirfenidone Attenuates Cardiac Fibrosis in a Mouse Model of TAC-Induced Left Ventricular Remodeling by Suppressing NLRP3 Inflammasome Formation

Priming with synthetic oligonucleotides attenuates pressure overload-induced inflammation and cardiac hypertrophy in mice

(2012) Markus Velten et al.   CARDIOVASCULAR RESEARCH

Inflammasomes in wound healing and fibrosis

(2012) Carol M Artlett   JOURNAL OF PATHOLOGY

Progression of Myocardial Fibrosis Assessed With Cardiac Magnetic Resonance in Hypertrophic Cardiomyopathy

(2012) Giancarlo Todiere et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Nebivolol prevents myocardial fibrosis and diastolic dysfunction in salt-loaded spontaneously hypertensive rats

(2012) Dinko Susic et al.   Journal of the American Society of Hypertension

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Aldosterone Inhibits the Fetal Program and Increases Hypertrophy in the Heart of Hypertensive Mice

(2012) Feriel Azibani et al.   PLoS One

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease Pathways and Novel Therapeutic Targets in Hypertrophic Cardiomyopathy

(2011) Houman Ashrafian et al.   CIRCULATION RESEARCH

The antifibrotic agent pirfenidone inhibits angiotensin II-induced cardiac hypertrophy in mice

(2011) Takanori Yamazaki et al.   HYPERTENSION RESEARCH

Development and psychometric evaluation of the Treatment Adherence Questionnaire for Patients with Hypertension

(2011) Chunhua Ma et al.   JOURNAL OF ADVANCED NURSING

Pirfenidone for Diabetic Nephropathy

(2011) K. Sharma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Pirfenidone

(2011) Luca Richeldi et al.   NATURE REVIEWS DRUG DISCOVERY

In Vitro Effects of Pirfenidone on Cardiac Fibroblasts: Proliferation, Myofibroblast Differentiation, Migration and Cytokine Secretion

(2011) Qiang Shi et al.   PLoS One

Myocardial Fibrosis as an Early Manifestation of Hypertrophic Cardiomyopathy

(2010) Carolyn Y. Ho et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Plk1 Inhibitor BI 2536 Temporarily Arrests Primary Cardiac Fibroblasts in Mitosis and Generates Aneuploidy In Vitro

(2010) Bo Lu et al.   PLoS One