The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor

VEGF-C and VEGF-D Blockade Inhibits Inflammatory Skin Carcinogenesis

(2013) A. K. Alitalo et al.   CANCER RESEARCH

Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis

(2013) Pallavi Chaturvedi et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor Cell Vasculogenic Mimicry

(2012) Richard E.B. Seftor et al.   AMERICAN JOURNAL OF PATHOLOGY

CD133+ Melanoma Subpopulations Contribute to Perivascular Niche Morphogenesis and Tumorigenicity through Vasculogenic Mimicry

(2012) C.-Y. Lai et al.   CANCER RESEARCH

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells

(2012) Francesca Spinella et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Endothelin-1 cooperates with hypoxia to induce vascular-like structures through vascular endothelial growth factor-C, -D and -A in lymphatic endothelial cells

(2012) Emirena Garrafa et al.   LIFE SCIENCES

Identification of Endothelin-1 and NR4A2 as CD133-regulated genes in colon cancer cells

(2011) Maria Ausiliatrice Puglisi et al.   JOURNAL OF PATHOLOGY

Autocrine Endothelin-3/Endothelin Receptor B Signaling Maintains Cellular and Molecular Properties of Glioblastoma Stem Cells

(2011) Y. Liu et al.   MOLECULAR CANCER RESEARCH

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

(2011) C. C.-L. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Podoplanin-Fc reduces lymphatic vessel formation in vitro and in vivo and causes disseminated intravascular coagulation when transgenically expressed in the skin

(2010) L. N. Cueni et al.   BLOOD

Angiocrine Factors Modulate Tumor Proliferation and Motility through EphA2 Repression of Slit2 Tumor Suppressor Function in Endothelium

(2010) D. M. Brantley-Sieders et al.   CANCER RESEARCH

AACR Centennial Series: The Biology of Cancer Metastasis: Historical Perspective

(2010) J. E. Talmadge et al.   CANCER RESEARCH

Importance of tumor load in the sentinel node in melanoma: clinical dilemmas

(2010) Alexander C. J. van Akkooi et al.   Nature Reviews Clinical Oncology

Endothelin-1 Inhibits Prolyl Hydroxylase Domain 2 to Activate Hypoxia-Inducible Factor-1α in Melanoma Cells

(2010) Francesca Spinella et al.   PLoS One

Endothelin-1 Stimulates Lymphatic Endothelial Cells and Lymphatic Vessels to Grow and Invade

(2009) F. Spinella et al.   CANCER RESEARCH

Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors

(2009) Qinghai Liu et al.   JOURNAL OF NEURO-ONCOLOGY

Placenta growth factor augments endothelin-1 and endothelin-B receptor expression via hypoxia-inducible factor-1 

(2008) N. Patel et al.   BLOOD

A Novel Gene Expression Profile in Lymphatics Associated with Tumor Growth and Nodal Metastasis

(2008) S. Clasper et al.   CANCER RESEARCH

Vascular endothelium in cancer

(2008) Leonid L. Nikitenko   CELL AND TISSUE RESEARCH

Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy

(2007) Ronald J Buckanovich et al.   NATURE MEDICINE