Anti-YKL-40 antibody and ionizing irradiation synergistically inhibit tumor vascularization and malignancy in glioblastoma

Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

(2013) Lin Cheng et al.   CELL

Update on bevacizumab and other angiogenesis inhibitors for brain cancer

(2013) Mikael L Rinne et al.   EXPERT OPINION ON EMERGING DRUGS

Transdifferentiation of Glioblastoma Stem-Like Cells into Mural Cells Drives Vasculogenic Mimicry in Glioblastomas

(2012) S. Scully et al.   JOURNAL OF NEUROSCIENCE

Role of YKL-40 in the Angiogenesis, Radioresistance, and Progression of Glioblastoma

(2011) Ralph A. Francescone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A YKL-40-Neutralizing Antibody Blocks Tumor Angiogenesis and Progression: A Potential Therapeutic Agent in Cancers

(2011) M. Faibish et al.   MOLECULAR CANCER THERAPEUTICS

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Inhibitory Activity of YKL-40 in Mammary Epithelial Cell Differentiation and Polarization Induced by Lactogenic Hormones: A Role in Mammary Tissue Involution

(2011) Steve Scully et al.   PLoS One

A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry

(2010) S. El Hallani et al.   BRAIN

PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas

(2010) Hongwu Zheng et al.   CANCER CELL

CHI3L1 (YKL-40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells

(2010) Bo Mi Ku et al.   INTERNATIONAL JOURNAL OF CANCER

Bevacizumab and Recurrent Malignant Gliomas: A European Perspective

(2010) Wolfgang Wick et al.   JOURNAL OF CLINICAL ONCOLOGY

Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

(2010) Olga Méndez et al.   Molecular Cancer

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

(2010) Lucia Ricci-Vitiani et al.   NATURE

Glioblastoma stem-like cells give rise to tumour endothelium

(2010) Rong Wang et al.   NATURE

Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme

(2009) Joost JC Verhoeff et al.   BMC CANCER

Antiangiogenic therapies for high-grade glioma

(2009) Andrew D. Norden et al.   Nature Reviews Neurology

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

(2009) R Shao et al.   ONCOGENE

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

(2008) Hongwu Zheng et al.   NATURE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neural Stem Cell Targeting of Glioma Is Dependent on Phosphoinositide 3-Kinase Signaling

(2008) Stephen E. Kendall et al.   STEM CELLS