Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKC , Stat3 and neuroendocrine markers

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Genetic Ablation of PKC Epsilon Inhibits Prostate Cancer Development and Metastasis in Transgenic Mouse Model of Prostate Adenocarcinoma

(2011) B. B. Hafeez et al.   CANCER RESEARCH

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), isolated from Plumbago zeylanica, inhibits ultraviolet radiation-induced development of squamous cell carcinomas

(2011) J. M. Sand et al.   CARCINOGENESIS

Oral infusion of pomegranate fruit extract inhibits prostate carcinogenesis in the TRAMP model

(2011) V. M. Adhami et al.   CARCINOGENESIS

Transgenic overexpression of PKCε in the mouse prostate induces preneoplastic lesions

(2011) Fernando Benavides et al.   CELL CYCLE

Prognostic impact of nm23-H1 and PCNA expression in pathologic stage I non-small cell lung cancer

(2011) Chengying Liu et al.   JOURNAL OF SURGICAL ONCOLOGY

Targeting Tyrosine Phosphorylation of PCNA Inhibits Prostate Cancer Growth

(2011) H. Zhao et al.   MOLECULAR CANCER THERAPEUTICS

Regulation of Prostate Cancer Cell Survival by Protein Kinase Cϵ Involves Bad Phosphorylation and Modulation of the TNFα/JNK Pathway

(2010) John Meshki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase Cɛ mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression and cell invasion in various human cancer cell lines through integration with MAPK cascade (RAF-1, MEK1/2 and ERK1/2)

(2010) M H Aziz et al.   ONCOGENE

Plumbagin, Isolated from Plumbago zeylanica, Induces Cell Death through Apoptosis in Human Pancreatic Cancer Cells

(2010) Chien-An Chen et al.   PANCREATOLOGY

Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

(2009) Tae Gen Son et al.   JOURNAL OF NEUROCHEMISTRY

Plumbagin, a Medicinal Plant–Derived Naphthoquinone, Is a Novel Inhibitor of the Growth and Invasion of Hormone-Refractory Prostate Cancer

(2008) Moammir H. Aziz et al.   CANCER RESEARCH

Plumbagin-induced Apoptosis in Human Prostate Cancer Cells is Associated with Modulation of Cellular Redox Status and Generation of Reactive Oxygen Species

(2008) Anna A. Powolny et al.   PHARMACEUTICAL RESEARCH

Dissociation of Epithelial and Neuroendocrine Carcinoma Lineages in the Transgenic Adenocarcinoma of Mouse Prostate Model of Prostate Cancer

(2007) Teresa Chiaverotti et al.   AMERICAN JOURNAL OF PATHOLOGY

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells

(2007) Clay C.C. Wang et al.   CANCER LETTERS