Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway

Role of nuclear factor-κB-mediated inflammatory pathways in cancer-related symptoms and their regulation by nutritional agents

(2011) Subash C Gupta et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

A distinct DNA methylation profile associated with microsatellite and chromosomal stable sporadic colorectal cancers

(2011) Andrew Silver et al.   INTERNATIONAL JOURNAL OF CANCER

Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

(2010) Frédéric Varnat et al.   EMBO Molecular Medicine

Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer

(2010) Lingyun Wei et al.   INTERNATIONAL JOURNAL OF CANCER

Expression and epigenetic modulation of sonic hedgehog-GLI1 pathway genes in neuroblastoma cell lines and tumors

(2010) Mehdi H. Shahi et al.   TUMOR BIOLOGY

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nuclear factor kappaB-activated monocytes contribute to pancreatic cancer progression through the production of Shh

(2009) Akio Yamasaki et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe

(2009) B. B. Aggarwal et al.   CLINICAL CANCER RESEARCH

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

(2009) Frédéric Varnat et al.   EMBO Molecular Medicine

Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling

(2009) Frédéric Varnat et al.   MECHANISMS OF DEVELOPMENT

Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters

(2009) Xiangsheng Fu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth

(2009) Valérian Dormoy et al.   Molecular Cancer

Chemotherapy, Bevacizumab, and Cetuximab in Metastatic Colorectal Cancer

(2009) Jolien Tol et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation

(2008) Shuntaro Nagai et al.   CANCER SCIENCE

Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation

(2008) Xiaoyun Liao et al.   CARCINOGENESIS

Characterization of sonic hedgehog as a novel NF-κB target gene that promotes NF-κB-mediated apoptosis resistance and tumor growth in vivo

(2008) Hubert Kasperczyk et al.   FASEB JOURNAL

Cadherins and cancer: how does cadherin dysfunction promote tumor progression?

(2008) A Jeanes et al.   ONCOGENE

Association of hyperhomocysteinemia and folate deficiency with colon tumors in patients with inflammatory bowel disease

(2007) Jean Marc Phelip et al.   INFLAMMATORY BOWEL DISEASES