3D-nanostructured scaffold electrodes based on single-walled carbon nanotubes and nanodiamonds for high performance biosensors

We report a novel strategy for controlled nanostructuring of electrodes surfaces using single-walled nanotubes and nanodiamonds in order to form highly porous structures for biosensors applications. These nanostructures were obtained by subsequent deposition of nanotubes and nanodiamonds followed by functionalization of this assembly with pyrenenitrilotriacteic acid (NTA) via dip coating. The electropolymerizaton of the pyrene derivative leads to a reinforcement of the structure and allows simultaneously the immobilization of biotin labeled bioreceptor units via coordinative affinity interactions. By using biotin modified glucose oxidase (B-GOx) as model bioreceptor, we could obtain impressive maximum current densities and sensitivities up to 465 mu A cm(-2) and 85.78 mA M-1 cm(-2), respectively. (C) 2013 Elsevier Ltd. All rights reserved.