期刊
CARBOHYDRATE RESEARCH
卷 357, 期 -, 页码 83-89出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2012.04.007
关键词
Termitomyces robustus var.; Mushroom polysaccharide; beta-Glucan; NMR spectroscopy; Immunostimulation
资金
- DST, Govt. of India [SR/S1/OC-52/2006]
- CSIR
- UGC
Two immunostimulating beta-glucans, PS-I (water soluble) and PS-II (water insoluble) isolated from hot water extract of the fruiting bodies of an edible mushroom Termitomyces robustus var. showed significant macrophage, splenocyte, and thymocyte activation. On the basis of total hydrolysis, methylation analysis, periodate oxidation, and NMR experiments (H-1, C-13, DQF-COSY, TOCSY, DEPT-135, HSQC, and HMBC), the structure of the repeating unit of the polysaccharides is established as: PS-I: -> 6)-beta-D-Glcp-(1 -> (Water-soluble glucan) PS-II: -> 3)-beta-D-Glcp-(1 -> 3)-beta-D-Glcp-(1 -> 6 up arrow 1 beta-D-Glcp (Water-insoluble glucan, Termitan) (C) 2012 Elsevier Ltd. All rights reserved.
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