Article
Biochemistry & Molecular Biology
Ma Angeles Garofalo, Pedro Villon, Fabiola Cornejo, Cristina M. Rosell
Summary: This study investigates the effects of modification processes on the nutritional and functional properties of banana starch. The results show that heat moisture treatment and dual modification can decrease resistant starch content and increase slow-digested starch content. Furthermore, the modifications also improve the structural and thermal stability of the starch, making it suitable for applications as a thickening agent in beverages and compotes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Plant Sciences
Juhua Liu, Mengting Liu, Jingyi Wang, Jing Zhang, Hongxia Miao, Zhuo Wang, Caihong Jia, Jianbin Zhang, Biyu Xu, Zhiqiang Jin
Summary: The study identified the MaMADS36 transcription factor gene as a crucial regulator in banana fruit, controlling processes like ethylene biosynthesis, starch degradation, softening, and sugar accumulation. MaMADS36 was found to directly interact with the MaBAM9b gene, enhancing its transcription activity and influencing starch degradation during fruit ripening.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Plant Sciences
Wenjing Zhang, Yan Zhao, Lingyu Li, Xu Xu, Li Yang, Zheng Luo, Beibei Wang, Shangyu Ma, Yonghui Fan, Zhenglai Huang
Summary: Short-term low temperature stress during the booting stage reduces the activities of key starch synthesis enzymes in wheat grains, leading to decreased starch accumulation, lower filling rate, and ultimately reduced grain yields.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Plant Sciences
Yunyi Xiao, Ying Li, Lejun Ouyang, Aiguo Yin, Bo Xu, Ling Zhang, Jianye Chen, Jinfeng Liu
Summary: A transcription factor called MaAP2a was found to negatively regulate starch breakdown during banana fruit ripening. MaAP2a acts by binding to the promoters of starch degradation-related genes and suppressing their expression at the transcriptional level. This discovery enhances our understanding of banana fruit ripening and provides insights for banana varietal improvement.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Food Science & Technology
Hangcong Chen, Xiuhua Lai, Lihua Wang, Xueping Li, Weixin Chen, Xiaoyang Zhu, Zunyang Song
Summary: In this study, researchers identified a transcription factor called MaERF012 that plays a crucial role in regulating fruit yellowing and softening in bananas. They found that MaERF012 activates the transcription of genes involved in chlorophyll degradation, starch degradation, and cell wall degradation, thereby promoting fruit ripening. The overexpression of MaERF012 also altered the transcriptome profiles of the fruit peel and pulp, affecting genes related to starch and sucrose metabolism, plant hormone signal transduction, and secondary metabolism. These findings provide new insights into the molecular mechanisms underlying banana fruit ripening.
Article
Biochemistry & Molecular Biology
Lisha Zhu, Lin Chen, Chaojie Wu, Wei Shan, Danling Cai, Zengxiang Lin, Wei Wei, Jianye Chen, Wangjin Lu, Jianfei Kuang
Summary: This study reveals a novel regulatory network involving MaMsrA4-mediated redox regulation of the ethylene signaling component MaEIL9 in banana fruit ripening. MaEIL9 plays a positive role in banana fruit ripening. The oxidation of methionines in MaEIL9 leads to the loss of its specific functions.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2023)
Article
Chemistry, Applied
Ze Yun, Huijun Gao, Xi Chen, Xuewu Duan, Yueming Jiang
Summary: Experiments showed that hydrogen water treatment delayed banana ripening by reducing ethylene production and respiratory rate, as well as slowing down chlorophyll degradation and cell wall degradation. It maintained fruit firmness and increased starch content in the fruit pulp.
Review
Agronomy
Guowu Yu, Yuanzhu Gaoyang, Lun Liu, Noman Shoaib, Yawen Deng, Na Zhang, Yangping Li, Yubi Huang
Summary: This article summarizes the main research on starch synthase III (SSIII), including its biochemical characteristics, structural features, expression atlas, and regulation means. The study found that SSIIIa is the main functional protein in maize endosperm and can affect the activity of other key enzymes in starch synthesis through protein-protein interactions.
Article
Biochemistry & Molecular Biology
Hangcong Chen, Zunyang Song, Lihua Wang, Xiuhua Lai, Weixin Chen, Xueping Li, Xiaoyang Zhu
Summary: Cold stress inhibits banana fruit ripening by affecting the softening and de-greening processes. The mechanism of ripening disorder caused by chilling injury (CI) in banana fruit is largely unknown. MaIAA17-like gene was found to be involved in fruit softening and de-greening in 'Fenjiao' banana.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Agronomy
Juhua Liu, Mengting Liu, Caihong Jia, Jing Zhang, Hongxia Miao, Jingyi Wang, Jianbin Zhang, Zhuo Wang, Biyu Xu, Xinguo Li, Zhiqiang Jin
Summary: This study elucidates the molecular mechanism underlying the cooperative regulation of MaGWD1-mediated starch degradation by MaMADS36 and MaMADS55. The findings contribute to our understanding of how transcription factors regulate starch degradation in banana fruit and have potential implications for improving fruit quality and supporting the banana industry.
POSTHARVEST BIOLOGY AND TECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Elumalai Sanniyasi, Rajesh Kanna Gopal, Dinesh Kumar Gunasekar, Preethy P. Raj
Summary: The study identified a potential microalga, Uronema africanum Borge, isolated from a waste plastic bag, capable of degrading LDPE sheet in a BBM culture medium. The microalga exhibited degradation of LDPE within 30 days of incubation, showcasing its potential as a biodegradation solution for polyethylene pollution.
SCIENTIFIC REPORTS
(2021)
Article
Food Science & Technology
Guiyuan Xiang, Jiangtao Li, Wenfang Han, Yaqin Yang, Qinlu Lin, Ying Yang, Qiongxiang Liu, Xiaofeng Guo, Qianru Pan, Zhengyu Huang, Lingxue Cao
Summary: This study investigated the effects of annealing on the structural and physicochemical properties of rice starch. The results showed that annealing improved the gelatinization temperature of rice starch but decreased its solubility and viscosity. The temperature and method of annealing also affected the rearrangement of starch molecules and the crystalline structure.
Article
Biochemistry & Molecular Biology
Liping Li, Ranran Chang, Jinling Zhan, Hao Lu, Xiaoxue Lu, Yaoqi Tian
Summary: Non-crystalline granular starch (NCGS) was successfully prepared at 210 degrees C, showing lower processing viscosity, decreased crystallinity, and increased amylose content. This enhances efficiency and reduces environmental pollution in industrial starch applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Polymer Science
Herlina Marta, Yana Cahyana, Mohamad Djali, Giffary Pramafisi
Summary: This review examines the chemical composition, granule morphology, crystallinity, pasting, thermal properties, and digestibility of banana starch, and discusses the various modifications and potential applications of banana starch in the food industry.
Article
Biology
Anuradha Ravi, Perla Troncoso-Rey, Jennifer Ahn-Jarvis, Kendall R. Corbin, Suzanne Harris, Hannah Harris, Alp Aydin, Gemma L. Kay, Thanh Le Viet, Rachel Gilroy, Mark J. Pallen, Andrew J. Page, Justin O'Grady, Frederick J. Warren
Summary: This study evaluated the species-level compositional variation within a single microbiome in response to six structurally distinct carbohydrates using hybrid metagenome assemblies. The researchers identified several uncultured bacterial species with the potential to degrade starch substrates and found an increase in abundance of bacteria carrying genes encoding starch binding modules in response to starches.
COMMUNICATIONS BIOLOGY
(2022)
Review
Materials Science, Ceramics
Andressa da Cruz Schneid, Lindomar Jose Calumby Albuquerque, Gabriela Borba Mondo, Marcelo Ceolin, Agustin Silvio Picco, Mateus Borba Cardoso
Summary: This review article provides an overview of the common and promising strategies for generating colloidally stable silica nanoparticles (NPs) in simulated biological fluids, and highlights the latest advances in producing degradable silica-based structures. The article emphasizes the potential of silica NPs as versatile nano-platforms for imaging and disease treatment, while acknowledging the challenges arising from their colloidal stability loss and possible aggregation and degradation in biological fluids. Strategies to overcome these challenges, such as surface functionalization and chemical modification, are discussed. The article underscores the importance of understanding the behavior of silica NPs in body fluids for the approval of nanomedicines and calls for further research on the dynamics, thermodynamics, biological response, and structural parameters of silica-based NPs.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2022)
Article
Nutrition & Dietetics
Bruna J. Quintanilha, Daniela F. S. Chaves, Elisa Brasili, Telma A. F. Correa, Vinicius Cooper Capetini, Frederico Moraes Ferreira, Inar A. Castro, Neuza M. A. Hassimotto, Marcelo M. Rogero, Franco M. Lajolo
Summary: This study found that the intake of high-fat, high-carbohydrate (HFHC) meals with orange juice can modulate the expression of miRNAs linked to pancreatic beta-cell function. In a crossover design study involving twelve healthy subjects, it was observed that the intake of HFHC meal + orange juice increased the expression of plasma miR-375, which is a biomarker of pancreatic beta-cell function, and contributed to preventing hyperglycemia.
CLINICAL NUTRITION ESPEN
(2022)
Article
Engineering, Biomedical
Maxwell de Paula Cavalcante, Livia Rodrigues de Menezes, Elton Jorge da Rocha Rodrigues, Maria Ines Bruno Tavares
Summary: The use of regeneration scaffolds, including poly(3-hydroxybutyrate)-PHB and nanohydroxyapatite-Hap composites, in bone tissue engineering shows promising potential due to their biocompatibility and mechanical properties.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Thiecla Katiane Osvaldt Rosales, Neuza Mariko Aymoto Hassimotto, Franco Maria Lajolo, Joao Paulo Fabi
Summary: Anthocyanins are important phenolic compounds responsible for pigment in plants. Regular intake of anthocyanins can reduce the risk of diseases in humans. However, molecular instability and digestion process can lead to low absorption and bioavailability of anthocyanins. Studies have been conducted to find alternatives to improve stability and protect against degradation by intestinal microbiota, including the use of nanotechnology systems.
Review
Nutrition & Dietetics
Hilton Cesar Rodrigues Magalhaes, Deborah dos Santos Garruti, Eliezer Avila Gandra, Eduardo Purgatto
Summary: The stage of ripeness determines the aromatic profiles of fruits, and the composition of volatile compounds plays a crucial role in fruit quality. Postharvest treatments have a direct impact on the biosynthesis of volatile compounds, with hormonal treatments and other postharvest treatments exhibiting different effects.
CURRENT NUTRITION & FOOD SCIENCE
(2023)
Article
Food Science & Technology
Lais Moro, Renata Vieira da Mota, Eduardo Purgatto, Fulvio Mattivi, Panagiotis Arapitsas
Summary: This study investigated the impact of methyl jasmonate (MeJa) treatment on grape juice production in two Brazilian regions using two Vitis labrusca cultivars. The results showed that MeJa treatment significantly improved the anthocyanic profile of Isabel Precoce juices. Furthermore, the concentration of hydroxycinnamates, especially their glucosides, increased with MeJa treatment. New biomarkers of MeJa treatment were identified, indicating a possible positive effect on the antioxidant properties of grape juice.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Plant Sciences
Ximena Chirinos, Shiyu Ying, Maria Aurineide Rodrigues, Elie Maza, Anis Djari, Guojian Hu, Mingchun Liu, Eduardo Purgatto, Sylvie Fournier, Farid Regad, Mondher Bouzayen, Julien Pirrello
Summary: The transition to fruit ripening is a complex process that involves multihormonal control, starting in the locular tissue before extending to the pericarp. This study reveals the transcriptomic reprogramming associated with tomato fruit ripening and highlights the crucial role of auxin in the initiation of ripening.
Article
Nutrition & Dietetics
Layanne Nascimento Fraga, Dragan Milenkovic, Franco Maria Lajolo, Neuza Mariko Aymoto Hassimotto
Summary: This study identified novel polymorphisms associated with higher absorption of flavanones, providing a basis for personalized nutritional guidelines for consuming flavanone-rich foods for better health benefits.
Editorial Material
Biotechnology & Applied Microbiology
Juliana Sakamoto Yoneda, Mateus Borba Cardoso
Article
Polymer Science
Bruna Vieira Tiburcio, Livia Rodrigues de Menezes, Laura Coelho Merat, Lizandra Viana Maurat da Rocha, Emerson Oliveira da Silva, Maria Ines Bruno Tavares
Summary: Orange oil was encapsulated in PCL/Pluronic F68-based nanoparticles prepared by the nanoprecipitation technique. The encapsulation improved the solubility of orange oil and maintained its properties. The nanosystems had monodispersed distributions and nanometric diameters. The encapsulated orange oil exhibited stabilizing and cryoprotective effects on the colloidal dispersions, and its release sustained for approximately 7 h.
Review
Nanoscience & Nanotechnology
Xiumin Li, Yalin Cong, Muhammad Ovais, Mateus Borba Cardoso, Saima Hameed, Rui Chen, Mingli Chen, Liming Wang
Summary: Drug-resistant bacteria and highly infectious viruses are major threats to global health, and novel strategies are urgently needed to address this challenge. Copper-based nanoparticles (CBNPs) have exhibited broad antimicrobial capacity and have gained increasing attention. This review describes the functionalization of CBNPs, their antibacterial and antiviral activity, applications, as well as toxicity, biodistribution, and persistence. The limitations of current studies and potential solutions are also briefly discussed. This review will guide the rational design of functional nanomaterials for antimicrobial applications.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
(2023)
Article
Plant Sciences
Renata A. Carnauba, Flavia M. Sarti, Neuza M. A. Hassimotto, Franco M. Lajolo
Summary: Studies have found significant disparities in bioactive compound consumption across populations depending on their geographic origin. The aim of this research was to estimate the intake of bioactive compounds in different regions of Brazil and identify the major contributors. The study analyzed data from the National Dietary Survey 2017-2018, including food intake information from 46,164 individuals aged ≥10 years. The results showed variations in the intake of polyphenols and carotenoids across different regions, with the South having higher polyphenol intake and the Midwest having higher carotenoid intake. Tea and coffee were the main contributors to polyphenol intake in different regions, while acai, caja juice, mango, and corn were important sources of carotenoid intake in specific regions. The findings highlight the potential of food plants in developing marketable products and increasing bioactive compound intake.
Article
Chemistry, Multidisciplinary
Karim Bouchmella, Quentin Lion, Christel Gervais, Mateus Borba Cardoso
Summary: The mesoporous SBA-15 material was functionalized with amino and carboxylic acid groups and used to study their interaction with tetracycline, kanamycin, and ampicillin antibiotics. The study employed two-dimensional 1H-13C HETCOR CP MAS and FTIR spectroscopy to characterize the interactions between the antibiotics and the functionalized surfaces, revealing the formation of -COO-NH3+ bonds between the chemical groups on the silica surface and the drug molecules. Surface modification resulted in higher drug loadings and slow-release rates, and all synthesized systems exhibited antibacterial activity against susceptible Escherichia coli.
Article
Nanoscience & Nanotechnology
Iris Renata Sousa Ribeiro, Raquel Frenedoso da Silva, Renata Santos Rabelo, Talita Miguel Marin, Jefferson Bettini, Mateus Borba Cardoso
Summary: Most nanomaterial-based medicines are administered through intravenous injection due to challenges associated with oral administration, such as interactions with digestive fluids and transport through the intestinal barrier. This study investigates the physicochemical stability of fluorescent silica nanoparticles passing through simulated gastrointestinal fluids and their absorption and transport across a model human intestinal epithelium barrier. The findings reveal a time-dependent nanoparticle transport and demonstrate the potential for rational design of oral-administered nanomedicines.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Engineering, Chemical
Matheus Farias, Paulo Sergio Rangel Cruz da Silva, Maria Ines Bruno Tavares, Mariana Sato de S. B. Monteiro
Summary: Nanocomposites with inorganic nanofillers were prepared using a solution intercalation technique and a spray-drying process. The results showed that PVP/MMT achieved an intercalated/exfoliated morphology, while the incorporation of TiO2 nanoparticles did not affect the structure of the PVP matrix. Thermal analysis did not reveal any changes in the nanocomposites compared to the pure polymer. SEM analysis revealed a pseudo-spherical shape, and EDS confirmed the dispersion of MMT in the PVP matrix. The introduction of lithium carbonate created a new system with higher molecular mobility.
POLYMER ENGINEERING AND SCIENCE
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
