Article
Chemistry, Physical
Mwadham M. Kabandaa, Indra Bahadur
Summary: In this theoretical study, the preferred geometry arrangement of the cation/anion units in the [EMIM][DCA] ionic liquid and its interaction with a water co-solvent molecule were investigated for the first time. DFT and MP2 methods were used for comparison. The results showed that the cation/anion units in the ionic liquid are mainly stabilized by a combination of hydrogen bonding and dispersion interactions.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Kris Likit-anurak, Ishwor Karki, Ben I. Howard, Laura Murdock, Nikolai Mukhin, Jamie Brannon, Aubrey Hepstall, Bridgett Young, Sirivatch Shimpalee, Brian Benicewicz, Benjamin Meekins
Summary: We demonstrate the use of para-PBI membranes as replacements for Nafion membranes in aqueous HCl oxygen depolarized electrolyzers. Both para-PBI and densified para-PBI membranes reduce the cell voltage needed at 0.5 A cm-2 by >= 100 mV. Increased proton conductivity, measured as reduced area-specific membrane resistance, is identified as the primary mechanism to explain the improved performance of the electrolyzer.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Chemistry, Physical
Wenjin Cao, Qinqin Yuan, Hanhui Zhang, Xiaoguo Zhou, Steven R. Kass, Xue-Bin Wang
Summary: We conducted a study on glycine-chloride/bromide complexes (Gly center dot X-, X = Cl/Br) using negative ion photoelectron spectroscopy and quantum chemical computations, comparing them with the previously studied Gly center dot I- cluster ion. Through experimental and theoretical analysis, we found that different Gly center dot X- complexes adopt the same types of low-lying isomers with varying relative energies. Despite the congested spectral profiles, spectral assignments for Gly center dot Cl- and Gly center dot Br- were accomplished with the guidance from Gly center dot I-, which has well-resolved spectral peaks. This study investigates the binding patterns of glycine complexes with different halides, demonstrating that iodide-tagging is an effective spectroscopic method for unraveling diverse ion-molecule binding motifs in cluster anions with congested spectral bands.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Engineering, Chemical
Rifan Hardian, Abdulaziz Alammar, Tibor Holtzl, Gyorgy Szekely
Summary: Membrane technologies have shown promise as an energy-efficient alternative for separation processes in various industries. This study focuses on the fabrication of oil and solvent-resistant nanofiltration membranes using cellulose and chitosan blends. The membranes exhibited outstanding separation performance and chemical stability, even in harsh solvents. By adjusting the cellulose-chitosan ratio, the molecular sieving properties of the membranes could be fine-tuned. The membranes also showed biodegradation potential, contributing to the sustainable lifecycle of membranes.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Polymer Science
Elodie Melro, Filipe E. Antunes, Gabriela J. da Silva, Ines Cruz, Philippe E. Ramos, Fatima Carvalho, Luis Alves
Summary: The study focuses on the use of different acids to dissolve chitosan, with acetic acid showing the highest antimicrobial activity and solution viscosity, as well as better mechanical properties in the formed films. The selection of acid type not only facilitates chitosan dissolution but also plays a key role in the properties of the solutions and films.
Article
Multidisciplinary Sciences
Ezequiel R. Coscueta, Ana Sofia Sousa, Celso A. Reis, Manuela Pintado
Summary: PEITC, a chemopreventive compound with high reactivity, is limited in biomedical and food applications due to its low stability and bioavailability. Encapsulation of PEITC in polymeric microparticles improves its solubility in water and stability, maintaining bioactivity. Optimized microparticles using chitosan-olive oil-PEITC system showed high encapsulation efficiency and biocompatibility potential for various applications.
Article
Chemistry, Multidisciplinary
Yunying Xu, Aiyou Hao, Pengyao Xing
Summary: This study reports a weak halogen bond type that induces the formation of supramolecular helical structures in both solid and solution states. Experiments with p-conjugated phenylalanine derivatives show that hydrogen bonds and halogen bonds respectively drive 21 helical packings, with small bond energies.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Food Science & Technology
Cecile Miot-Sertier, Margot Paulin, Lucie Dutilh, Patricia Ballestra, Warren Albertin, Isabelle Masneuf-Pomarede, Joana Coulon, Virginie Moine, Amelie Vallet-Courbin, Julie Maupeu, Marguerite Dols-Lafargue
Summary: Chitosan is an active polysaccharide that has been developed for eliminating spoilage yeast in winemaking. The antimicrobial efficiency of chitosan on various wine microorganisms has been investigated, showing that most species are affected to some extent. The study also highlights that the efficiency of chitosan varies depending on wine parameters and stages of winemaking. Chitosan treatment is not suitable for limiting microbial pressure in musts and has limited impact on certain microorganisms such as Saccharomyces cerevisiae and acetic acid bacteria. Different types of chitosan have different antimicrobial properties, with lower molecular weight chitosan being more effective.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2022)
Article
Polymer Science
Chenkai Sun, Hai Yin, Junwei He, Liming Zou, Yongjing Xu
Summary: Gelatin/chitosan-poly (ethylene oxide) electrospun membranes at different weight ratios were successfully fabricated using acetic acid solution. The membranes showed uniform fibers and excellent properties, with potential applications as dermis scaffolds in skin regeneration.
JOURNAL OF POLYMER RESEARCH
(2021)
Article
Engineering, Chemical
Waseem Raza, Jixuan Wang, Jianhua Yang, Toshinori Tsuru
Summary: The review discusses the advancements in pervaporation membranes for the dehydration of acetic acid/water mixture, highlighting the challenge of balancing membrane hydrophilicity and acid resistance. It also explores the commercial prospects and challenges of acid-resistant membranes, emphasizing the importance of using such membranes for esterification reactions to improve yield.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Nusrat Sharmin, Jan Thomas Rosnes, Leena Prabhu, Ulrike Bocker, Morten Sivertsvik
Summary: In this study, chitosan solutions were prepared using different acid concentrations. It was found that citric acid solutions had lower tensile strengths but higher elongation at break values, which increased with an increasing citric acid content. Acid concentrations did not have a significant effect on gelation time, but citric acid solutions showed higher viscosities. The water vapour transmission rates of citric acid-containing samples were lower, and all chitosan solutions suppressed the growth of test strains.
Article
Chemistry, Multidisciplinary
Andrew M. L. West, Nicholas Dominelli-Whiteley, Ivan V. V. Smolyar, Gary S. S. Nichol, Scott L. L. Cockroft
Summary: Crystallographic and computational studies suggest favourable interactions between polarizable arenes and halogen atoms. However, quantification of these interactions in solution has been hindered by the steric demands of the halogens. This study synthesized molecular balances and used H-1 NMR spectroscopy to quantify halogen-arene contacts in various solvents, revealing that the interaction trend is aligned with increasing exchange repulsion rather than dispersion.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Biochemistry & Molecular Biology
Steven van Terwingen, Ruimin Wang, Ulli Englert
Summary: The ditopic molecule HacacMePz combines two different Lewis basic sites and forms a crystalline adduct with TFDIB, showing additional short contacts.
Article
Engineering, Environmental
Sylvanus B. Ruvubu, Indrajit Roy
Summary: Malachite green was successfully adsorbed from aqueous solutions using magnetic chitosan nanoparticles coated with triglycine and 2-mercaptoethylamine hydrochloride. The adsorption process was optimized by considering factors such as pH, MG concentration, sorbent dosage, time, sonication or shaking, and temperature. The fabricated nanoadsorbents showed high MG removal efficiency under optimal conditions. This study provides insights into the potential application of magnetic chitosan nanoparticles for water purification.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Sang-Hee Park, Cong Yang, Nasser Ayaril, Gyorgy Szekely
Summary: In this study, more sustainable thin-film composite (TFC) membranes were designed and fabricated, utilizing shrimp farming waste chitosan and plant-based 2,5-furandicarboxaldehyde for interfacial polymerization on a upcycled polyethylene terephthalate porous support. The membrane separation performance was optimized, offering a new upper bound.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)