Article
Chemistry, Applied
Hong Yao, Shiyi Lu, Barbara A. Williams, Bernadine M. Flanagan, Michael J. Gidley, Deirdre Mikkelsen
Summary: This study compared relative and absolute abundance datasets to investigate the alterations of human fecal microbiota during in vitro fermentation of different types of dietary fiber. The results showed that the DF mixtures more efficiently supported microbial growth than individual components, and the absolute abundance data positively correlated with butyrate production.
FOOD HYDROCOLLOIDS
(2022)
Article
Plant Sciences
Sina Barghahn, Gregory Arnal, Namrata Jain, Elena Petutschnig, Harry Brumer, Volker Lipka
Summary: Plants detect microbe-associated molecular patterns (MAMPs) and danger-associated molecular patterns (DAMPs) through pattern recognition receptors (PRRs) on the plasma membrane, activating immune responses known as pattern-triggered immunity (PTI). Beta-1,3/1,4-glucan (beta-1,3/1,4-MLG) oligosaccharides found in monocot plant cell walls can act as both DAMPs and MAMPs in monocot and dicot plant species, triggering immune responses.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Shuang Liu, Long Chen, Wenjuan Duan, Zhaoqing Meng, Hongjing Dong, Xiao Wang
Summary: In this study, two polysaccharides were extracted and studied from different types of Massa Medicata Fermentata. The results showed that stir-frying significantly changed the physicochemical properties of the polysaccharides, resulting in reduced enzyme inhibition and increased antioxidant activity.
Article
Agriculture, Dairy & Animal Science
Sara Muhonen, Sophie Sadet-Bourgeteau, Veronique Julliand
Summary: Horses are herbivores and benefit from diets rich in forage compared to concentrate. This study compared the effects of different forage diets on hindgut microorganisms and found no significant differences in microbial concentrations. Further research on plant-fibre and forage diets is important for horse feeding practices.
Article
Agriculture, Dairy & Animal Science
Sara Muhonen, Christelle Philippeau, Veronique Julliand
Summary: This study compares the effect of different grass fibre maturity and legume forage on the water-holding capacity and fluid balance of horses. The results indicate that early harvested forage may benefit the fluid balance of athletic horses without increasing body weight.
Article
Biochemistry & Molecular Biology
Ruslan Bikmurzin, Rimante Bandzeviciute, Arunas Marsalka, Andrius Maneikis, Lilija Kalediene
Summary: Beta-glucans are biological response modifiers which may vary in structure and activity based on different sources. The hot water extraction method allows for obtaining high molecular weight beta-glucans without altering their structure, and analysis by FT-IR and NMR spectroscopy is crucial for studying the preserved structure of these polysaccharides.
Review
Biotechnology & Applied Microbiology
Zorica Ubiparip, Marc De Doncker, Koen Beerens, Jorick Franceus, Tom Desmet
Summary: Beta-glucan phosphorylases are important carbohydrate-active enzymes with great potential for the biocatalytic synthesis of beta-glucans. Their preference for sugar phosphates highlights their significance in the carbohydrate industry.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Review
Immunology
Theodore J. Kottom, Eva M. Carmona, Andrew H. Limper
Summary: Pneumocystis jirovecii is a common fungal pathogen in immunocompromised individuals, causing significant host immune response driven by cell wall components. These components interact with CLRs, leading to activation of proinflammatory signaling pathways. This minireview summarizes known CLR/Pneumocystis interactions.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Md Faruque Ahmad, Fakhruddin Ali Ahmad, Mohammed Idreesh Khan, Abdulrahman A. Alsayegh, Shadma Wahab, M. Intakhab Alam, Faiyaz Ahmed
Summary: Ganoderma lucidum polysaccharides and triterpenoids are the major bioactive compounds with immunomodulatory and antiviral properties, playing a potential role in preventing and treating various diseases by enhancing the immune system and producing immune responses.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Alejandra Arevalo-Gallegos, Sara P. P. Cuellar-Bermudez, Elda M. M. Melchor-Martinez, Hafiz M. N. Iqbal, Roberto Parra-Saldivar
Summary: This study evaluated maltodextrin/alginate and β-glucan/alginate mixtures as wall materials for microencapsulation of Schizochytrium sp. oil, an important source of DHA. Both mixtures exhibited shear-thinning behavior, with higher viscosity in β-glucan/alginate. Maltodextrin/alginate showed more homogeneous morphology and higher oil-encapsulation efficiency (90%) compared to β-glucan/alginate (80%). Furthermore, maltodextrin/alginate microcapsules displayed prolonged stability, while β-glucan/alginate microcapsules degraded under high temperature. Therefore, maltodextrin/alginate is a suitable wall material for microencapsulation of Schizochytrium sp. oil, providing high oil-encapsulation efficiency and stable microcapsules.
Review
Polymer Science
Gemilang Lara Utama, Lidya Oktaviani, Roostita Lobo Balia, Tita Rialita
Summary: Biopolymers such as beta-glucan, mannoprotein, and chitin in yeast cell walls can be used as viable encapsulants for probiotics. Beta-glucan, due to its thermal stability, is suitable for cryoprotection during freeze-drying. Mannoprotein enhances the adhesion of probiotic microorganisms to intestinal epithelial cells.
Review
Biochemistry & Molecular Biology
Betty Schwartz, Vaclav Vetvicka
Summary: The occurrence of microbial challenges in commercial poultry farming leads to significant economic losses, and antibiotics have been widely used to control diseases. However, with the increasing problem of antibiotic resistance, producers are under pressure to reduce antibiotic use and are looking for feed additives to stimulate the immune system of poultry to resist microbial infection.
Article
Agriculture, Multidisciplinary
Zhaojun Peng, Yuhong Jin
Summary: The study showed that endo-1,4-beta-xylanase extracted from wheat malt can effectively degrade non-water-extractable wheat-derived arabinoxylan, producing water-extractable arabinoxylan and xylooligosaccharides. The enzyme's degradation process results in changes in molecular weight and oligosaccharide content.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Food Science & Technology
Nida Kanwal, Imran Pasha, Rizwan Shukat, Anjum Zia
Summary: This study investigates the bread-making characteristics of barley varieties with different concentrations of non-starch polysaccharides (NSPs) and shows a great potential for developing fiber-enriched bread using barley varieties comprising high NSPs.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Article
Agriculture, Dairy & Animal Science
Zijie Wang, Wenhui Wang, Song Xu, Jian Ding, Xiangfang Zeng, Hu Liu, Fenglai Wang
Summary: The effects of finely ground wheat bran on nutrient digestibility, digesta passage rate, and gut microbiota structure in sows were investigated. The results showed that the addition of finely ground wheat bran reduced the passage rate of digesta, increased the abundance of beneficial microorganisms, and elevated the concentration of short-chain fatty acids and PYY in sows. These findings are important for improving satiety and intestinal microbial composition in sows.
Review
Agriculture, Multidisciplinary
G. Bosch, K. S. Swanson
Summary: The translation introduces the background information on insect-based pet foods for dogs and cats, highlighting the differences in taste preference between cats and dogs and the need for further studies to evaluate the suitability, safety, and health benefits of insect-based pet foods.
JOURNAL OF INSECTS AS FOOD AND FEED
(2021)
Article
Zoology
Annelies De Cuyper, Daniela E. Winkler, Thomas Tuetken, Guido Bosch, Juergen Hummel, Michael Kreuzer, Arturo Munoz Saravia, Geert P. J. Janssens, Marcus Clauss
Summary: The study demonstrates that although guinea pigs increase their dry matter intake on bamboo diet, the lignin and silica in bamboo have negative effects on digestion, resulting in low digestibility and slower body weight gain.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY
(2022)
Article
Agriculture, Multidisciplinary
G. Rossi, G. Bosch, L. Pisa, D. G. A. B. Oonincx
Summary: In this study, a 3D-printed pipette tip was designed and tested for manipulating housefly eggs. The results showed that the pipette tip allowed rapid and gentle manipulation of the eggs, with minimal damage, but reduced larval survival.
JOURNAL OF INSECTS AS FOOD AND FEED
(2022)
Article
Agriculture, Dairy & Animal Science
Ariane Maike Wehrmaker, Nynke Draijer, Guido Bosch, Atze Jan van der Goot
Summary: This study investigates the impact of the degree of refinement on the sustainability of plant-based dog food, and formulates optimal plant-based dog food recipes. The results show that using less refined ingredients can improve the sustainability of the food while fulfilling the nutritional requirements of dogs.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2022)
Article
Agriculture, Multidisciplinary
L. Pisa, D. G. A. B. Oonincx, G. Bosch, W. H. Hendriks
Summary: This study investigated the competition between housefly larvae and microorganisms for easily digestible carbohydrates, such as starch. The results showed that the highest wet yield and heaviest larvae were observed in sterilized chicken excreta with added starch. Moreover, substrates with added fructo-oligosaccharides had minimal yields and larval weights. The study also found differences in substrate temperature profiles and larval size distributions.
JOURNAL OF INSECTS AS FOOD AND FEED
(2022)
Article
Agriculture, Dairy & Animal Science
T. M. M. Bastiaansen, R. T. Benders, J. A. Dijksman, M. Thomas, W. H. Hendriks, S. de Vries, G. Bosch
Summary: Due to the growing demand for food, the use of co-products from the food and biofuel industry in livestock feed is expected to increase. However, these co-products, which are fiber-rich, can negatively affect pellet manufacturing, leading to reduced pellet quality and increased energy costs. This study aimed to investigate the impact of including fibrous co-products in feed on their thermomechanical properties and subsequent effects on pellet manufacturing.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2023)
Article
Nutrition & Dietetics
Evelien Bos, Wouter Hendriks, Bonne Beerda, Guido Bosch
Summary: In-home pet food testing provides directly applicable data to the pet population. This study investigated key requirements for an in-home canine food digestibility protocol, using 60 dogs of different breeds and ages. The results showed that one day of faecal collection yielded reliable digestibility values for all nutrients, and the minimal required sample size ranged from 9 to 43 dogs depending on the accepted margin of error.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Veterinary Sciences
E. Bos, W. H. Hendriks, B. Beerda, G. Bosch
Summary: In-home cat food digestibility testing has the potential to provide representative data, but there are currently no standardized protocols available. This study investigated key factors affecting variation in cat food digestibility, including adaptation period, fecal collection, and sample size. The findings suggest that a minimum of 2 adaptation days and 3 fecal collection days are needed for future in-home digestibility tests.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
T. M. M. Bastiaansen, R. T. Benders, S. de Vries, W. H. Hendriks, M. Thomas, G. Bosch, J. A. Dijksman
Summary: Pellet manufacturing is influenced by feed formulation, which affects the physicochemical properties of feed mash and subsequently impacts pellet quality and energy costs. Capillary rheometry provides a potential method for studying feed mash behavior under conditions similar to pellet manufacturing.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2023)
Article
Nutrition & Dietetics
Sylvie M-T. J. D'Hooghe, Guido Bosch, Mengmeng Sun, An Cools, Wouter H. Hendriks, Anne A. M. J. Becker, Geert P. J. Janssens
Summary: Feeding whole prey to felids benefits gastrointestinal health, but the impact of prey structure is unclear. This study found that the physical structure of mice diet did not significantly affect intestinal fermentation, but a shift in microbiota composition and a decrease in potentially harmful fermentation products were observed when transitioning from extruded to mice diet.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Agriculture, Dairy & Animal Science
Ronald J. J. Corbee, Jurriaan J. J. Mes, Govardus A. H. de Jong, Ronald T. M. van den Dool, Franka Neumer, Stephan Theis, Guido Bosch
Summary: The aim of this study was to compare the digestion and physiological effects of isomaltulose with other saccharides in dogs. The results showed that isomaltulose had a slower digestion and lower blood glucose response compared to sucrose. However, sucrose had a higher blood glucose response, suggesting the presence of an adaptive response. Therefore, further research on the digestion physiology of saccharides in dogs is warranted.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2023)
Meeting Abstract
Agriculture, Dairy & Animal Science
E. Bos, W. H. Hendriks, Guido Bosch, B. Beerda
JOURNAL OF ANIMAL SCIENCE
(2022)
Meeting Abstract
Agriculture, Dairy & Animal Science
Guido Bosch
JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Food Science & Technology
Ariane M. Wehrmaker, Hannah Elisabeth Zenker, Wouter de Groot, Mark Sanders, Atze Jan van Der Goot, Anja E. M. Janssen, Julia Keppler, Guido Bosch
Summary: Shear cell technology is a promising method for meat analogue production. This study investigated the effect of shearing and sterilization on the amino acids and oxidation markers in soy protein- and pea protein-based meat analogues. The results showed that processing led to modified amino acids and more pronounced oxidation in the pea-based analogue. Despite extensive thermal treatment, the impact on protein quality in plant-based products was comparable or less than that in animal-based pet food.
ACS FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Guido Bosch, Myrthe Gilbert, Bonne Beerda
Summary: Overweight and obesity are common in pet cat populations worldwide. Understanding how properties of food affect appetite is crucial. This study used a model of operant conditioning to assess the effects of protein, fiber, and meat preparation on cat appetite. The findings suggest that dietary protein and fiber levels, as well as meat grinding and cooking, influence cat appetite.
FRONTIERS IN ANIMAL SCIENCE
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
